... the ICOS-B7RP-1 interaction may be a candidate novel strategyfor the treatment of this intractable autoimmune disease.Competing interestsKatsunari Tezuka is an employee of Japan Tobacco, Inc. Allother authors ... antibody productionManabu Kawamoto1, Masayoshi Harigai1,2, Masako Hara1, Yasushi Kawaguchi1, Katsunari Tezuka3, Michi Tanaka1, Tomoko Sugiura1, Yasuhiro Katsumata1, Chikako Fukasawa1, ... Dental University, Tokyo, Japan3Central Pharmaceutical Research Institute, Japan Tobacco, Inc., Osaka, JapanCorresponding author: Masayoshi Harigai, mharigai.mpha@tmd.ac.jpReceived: 9 Aug...