Báo cáo y học: "De novo acute megakaryoblastic leukemia with p210 BCR/ABL and t(1;16) translocation but not t(9;22) Ph chromosome" pdf
Báo cáo y học: "De novo acute megakaryoblastic leukemia with p210 BCR/ABL and t(1;16) translocation but not t(9;22) Ph chromosome" pdf
... report of de novo AMKL with p210 BCR/ABL and der(16 )t(1;16)( q21;q23) translocation but not t(9;22) Ph chromosome. [Key words] Imatinib, Acute megakaryocytic leukemia, p210 BCR/ABL 9 suggested ... 24 × 10 9 /L, with 54% megakaryoblasts, 17% promegakaryocytes, 10% myelocytes, 8% band forms, 7% neutrophils, 3% lymphocytes, and 1% monocytes. Plasma D-dime...
Ngày tải lên: 10/08/2014, 21:23
Báo cáo y học: " De novo genome sequence assembly of a filamentous fungus using Sanger, 454 and Illumina sequence data" ppsx
... by DP. Assemblies were performed by SD, NYL, MS, SKC and DP. Data analysis was performed by SD, SKC, TRD and NYL under the direction of IB. The manuscript was prepared by SD, CB, JB and SJMJ with ... they generate short (typically 450 bp for 454; 50 to 100 bp for Illumina and SOLiD) reads that cannot resolve low complexity sequence regions or distributed repetitive elements; they ha...
Ngày tải lên: 09/08/2014, 20:20
Báo cáo y học: "Risk of acute myocardial infarction with nonselective non-steroidal anti-inflammatory drugs: a meta-analysis" ppsx
... adenomas and carcinomas. Cochrane Database Syst Rev 2004, 2:CD004079. 8. Cryer B, Feldman M: Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory drugs. ... defining effi- cacy and assigning causality, but their external validity or generalizability can often be low [34] and they are rarely suffi- ciently large or long running to identify a...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo Y học:Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor docx
... Cys-free DMEM supplemented with 10% dialyzed fetal bovine serum, 10 m M sodium butyrate, with or without 100 l M MG132 and with or without 1 m M castanospermine (CST). They were then pulsed for 1 ... supple- mented or not with MG132. Samples were analyzed by SDS/PAGE after a reduction step (A, B) and quantified by performing phos- phorimaging (C, D). (C) TSHR bearing high mannose...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo Y học: Toxicity of novel C-terminal prion protein fragments and peptides harbouring disease-related C-terminal mutations pdf
... 121–146(AVVGG LGYMLGSAMSRPIIHFGSDYED), PrP147– 171(RYYRE NMYRYPNQVYYRPVDQYSNQ), PrP163–184(RPVDQ YSNQNNFVHDCVNITIK), PrP180– 198(NITIKQHTVTT KGENFT) and PrP196–220(NFTETDVKMMERVVRQM CVTQYQKE). CD spectroscopy ... previously described [3]. Peptides or proteins were added to cultures initially and on the third day. Cell survival was determined on day 5 or 7. 3-(4,5-Dimethylthiazol-2-yl)-2,5...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo y học: "Infiltration of the synovial membrane with macrophage subsets and polymorphonuclear cells reflects global disease activity in spondyloarthropathy" pps
... SpA synovitis was characterized by higher vascularity and infiltration with CD163 + macrophages and polymorphonuclear leukocytes (PMNs) and by lower values for lining-layer hyperplasia, lymphoid ... cells, another type with diffuse infiltration by essentially T lym- phocytes and macrophages, and a third, granulomatous type, which is less frequent [9]. The different histological...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Adalimumab clinical efficacy is associated with rheumatoid factor and anti-cyclic citrullinated peptide antibody titer reduction: a one-year prospective study" potx
... at baseline and after 6 and 12 months of treatment with adalimu- mab by using enzyme-immunoassay (EIA) (Pharmacia Diag- nostics, Friburg, Germany); positive samples were also evaluated by Farr assay and ... mg per day), 48 received non-steroidal anti-inflammatory drugs and/ or analgesics, and 6 received other drugs. Patients were followed clinically at reg- ular intervals by the sa...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase" potx
... Sanofi Synthelabo) is used to prevent acute uric acid nephropathy caused by tumor lysis in patients with leukemia and lymphoma [7,8]. However, the 18 hour half-life, which necessitates daily infusion, ... asparaginase and polyethylene glycol conjugated asparaginase for treat- ment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: a Children's Can...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis" pdf
... was estimated after incubation with an alkaline phosphatase-conjugated swine anti-rabbit isotype-specific antibody (DakoCytomation, Glostrup, Denmark) and phosphatase substrate (Sigma- Aldrich, ... after day 66 in wild-type mice. COMP deficiency led to early onset of the disease, with a mean onset of arthritis at 37.5 ± 2.81 days in COMP-deficient mice compared with 48.4 ± 13.7 days i...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: "Archaeal phylogeny based on proteins of the transcription and translation machineries: tackling the Methanopyrus kandleri paradox" pdf
... adaptation to the very high intracellular salin- ity (1 M of cyclic 2,3-diphosphoglycerate) [23]. The resulting phylogeny was very similar to the transcription tree of Figure 2a, with M. kandleri emerging ... represented the most basal branch, with M. kandleri grouping paraphyletically with Methanococcales and Methanobacteriales (88% BP). Interestingly, M. kandleri displayed a very lo...
Ngày tải lên: 09/08/2014, 20:21