Báo cáo y học: "Significance of differential expression of thymidylate synthase in normal and primary tumor tissues from patients with colorectal cancer" ppsx

... Significance of differential expression of thymidylate synthase in normal and primary tumor tissues from patients with colorectal cancer. Journal of Hematology & Oncology 2011 4:33. Figure 1 Patients ... primary tumor cells. Thirty of them (39.49%) have showed higher level of TS in primary tumors than in normal tissues. To study the si...

Ngày tải lên: 10/08/2014, 21:23

... paraformaldehyde containing 0.85% sodium chloride and 10% acetic acid. Tissues were dehydrated in a series of ethanol solutions and infiltrated with xylene and before being embedded in paraffin and cut into ... hypoxic conditions. Since HIF-1α expression is associated with low O 2 , this factor may play a role in chondrocyte survival and the maintenance of fundamen...

Ngày tải lên: 09/08/2014, 06:23

... following tissue injury in the upper urinary tract. Since the role of TGF-β1 in lower urinary tract inflammation is currently unknown, and since gender-based differences exist in the setting of interstitial ... levels of NO 2 - / NO 3 - 6 h post-CYP, followed by a steady decline to levels Urinary profile and baseline levels of NO reaction productsFigure 1 Urinary profile a...

Ngày tải lên: 11/08/2014, 08:22

... to baseline levels of selected variables reflecting renal function, including creatinine clearance, level of 24-hour urinary protein excretion, serum albumin, activity index score, chronicity index score, ... b). Figure 1 Localization of metallothionein (MT) isoforms I + II in healthy kidneys and in lupus nephritisLocalization of metallothionein (MT) isoforms I + II in healthy...

Ngày tải lên: 09/08/2014, 10:23

... the duration of drainage, the day of maximum loss of chy- lou s and the type and duration of treatment (fatty acid- free MCT-enriched diet, TPN, octreotide, recanalisation of thrombosed veins by lysis, ... may appear due to injury of the thoracic duct, due to venous or lymphatic cong estion, central vein thrombosis, or diffuse injury of mediastinal lymphatic tissue in asso...

Ngày tải lên: 10/08/2014, 09:23

... efficiently into cells by attaching protein transduction domains to their amino-termini. One such protein transduction domain is derived from the TAT protein of HIV; Jeffrey Marx (Medtronics Inc., Minneapolis, ... previous meeting in this series, and further clinical trials seem likely. Introduction Every 3 years, a loosely affiliated network of investigators holds an informal, 2-da...

Ngày tải lên: 09/08/2014, 07:20

... inhibitor Apolipoprotein A α 1 -Antitrypsin PEDF Fibronectin Tetranectin Fibronectin Clustrin H 4 inhibitor α 1 -Antichymotrypsin Pregnancy zone protein Gelsolin α 1 -Acid glycoprotein Fibrinogen S100 Kinninogen ... rate of formation and breakdown of kinins results in the inflammation, joint pain, and swelling that are seen in patients with arthritis. Our analyses identify...

Ngày tải lên: 09/08/2014, 10:20

... directly by affecting its DNA-binding affinity or inter- action with accessory proteins at the promoter. Alternatively, or in addition, protein-lipid/sterol binding may positively or negatively affect ... variety of eukaryotic proteins implicated in signaling. PH domains are characterized by their ability to bind phosphoinositides, thereby influencing membrane and/ or protein interac...

Ngày tải lên: 09/08/2014, 20:20

... usually precedes the guanine nucleotide-binding NKXD motif by alanine and replacement of a conserved phenylalanine 10 residues C-terminal to the EXS[AV] motif by alanine, threonine, serine or ... contacts with other residues and water molecules involved in Mg 2+ and nucleotide binding [39]. Expression of Rab31, Rab32 and Rab11A in platelets Use of a ntibodies directed ag...

Ngày tải lên: 08/03/2014, 16:20

... peptide-independent pathway and calls for further investigation on this subject. Enzyme activity and specificity In the standard tricaprylin hydrolysis assay, rPFL displayed highest activity at 29 ... number of disulphide bridges, the location of proline and arginine residues, and hydrophobic core interactions are generally recognized as key factors in determining the flexibilit...

Ngày tải lên: 24/03/2014, 04:21