Báo cáo y học: "Histone deacetylases (HDACs) in XPC gene silencing and bladder cancer" pot
Báo cáo y học: "Histone deacetylases (HDACs) in XPC gene silencing and bladder cancer" pot
... HDACs may play
in XPC gene silencing and bladder cancer development,
we first determined the effect of HDAC inhibitor treat-
ment on activation of XPC gene transcription in HTB4
and HTB9 bladder ... determine the roles of these
epigenetic regulation mechanisms in XPC gene silencing
and bladder cancer development in order to pro vide a
better understanding o...
Báo cáo y học: "Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption" ppt
... gelatin zymography, and
collagenase activity assays using both SW1353
chondrosarcoma cells and primary human chondrocytes. The
HDAC inhibitors trichostatin A and sodium butyrate potently
inhibit ... collagenases, and
Figure 1
Histone deacetylase inhibitors block cartilage glycosaminoglycan and collagen loss induced by IL-1α/OSMHistone deacetylase inhibitors block cartilage glycosami...
Báo cáo y học: " Histone deacetylases — a new target for suppression of cartilage degradation" pdf
... mice
constitutively expressing Runx2. Conversely, mice over-
expressing HDAC4 in cartilage show greatly reduced
chondrocyte hypertrophy, similar to that in the Runx2-null
phenotype.
Commentary
Histone deacetylases ... objective.
In cartilage cultured in the presence of the cytokines interleukin-1
and oncostatin M, chondrocytes produce enhanced levels of
metalloproteinases of the A...
Báo cáo y học: "vitamin B12 status in patients of Turkish and Dutch descent with depression: a comparative cross-sectional study" pot
... B12 deficiency and hyperhomocysteinaemia
No vitamin B12
deficiency, mean (SD)
Vitamin B12
deficiency, mean (SD)
t Test P value No
hyperhomocysteinaemia,
mean (SD)
Hyperhomocysteinaemia,
mean ... optimal
resorption of vitamin B12 via atrophy of the abdominal
mucous membrane ensuing from infection [20]. Atrophy
results in an inadequate linking between the consumed
vitamin B12 and int...
Báo cáo y học: "Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis" pptx
... major
phenotypic shift occurs in OA toward a de-differentiated
chondrocyte [40]. Interestingly, in the present study we
observed increased amounts of types I and III collagens by
immunohistology in both ... meniscectomy). Changes in collagen
subtypes in pathological cartilage may not only influence the
biomechanical integrity of the tissue but may sequester and
modulate the acti...
Báo cáo y học: "Serum IL-15 in patients with early systemic sclerosis: a potential novel marker of lung disease" potx
... correlated inversely with the systolic blood pressure by
multiple linear regression analysis including variables that may
influence the systolic blood pressure (Table 3). Age and the
body mass index ... with systemic-sclerosis-related antibodies and markers for inflammatory activity. Inflammatory
activity describes an increased erythrocyte sedimentation rate, increased C-reactive protein...
Báo cáo y học: "Traditional herbal medicine in Far-west Nepal: a pharmacological appraisal" potx
... Chiang CL, Hsieh YS: Mulberry
anthocyanins, cyanidin-3-rutinoside and cyanidin-3-glucoside, exhibited
an inhibitory effect on the migration and invasion of a human lung
cancer cell line. Cancer Letters ... of
dietary caraway (Carum carvi L.) on aberrant crypt foci development,
fecal steroids, and intestinal alkaline phosphatase activities in 1,2-
dimethylhydrazine-induced colon carcin...
Báo cáo y học: " Postresectional lung injury in thoracic surgery pre and intraoperative risk factors: a retrospective clinical study of a hundred forty-three cases" pptx
... vast
majority of respiratory-related deaths [2].
ARDS formally defined as a syndrome of inflammation
and increased permeability, is associated with a constella-
tion of clinical, radiological and physiological ... lung
resection [1]. Respiratory complications remain the
major cause of morbidity and mortality following lung
resection. Acute lung injury (ALI) and acute respiratory
disea...
Báo cáo y học: " Human herpesvirus-8 in northwestern China: epidemiology and characterization among blood donors" pdf
... resid-
inginXinjiangthanintheinlandareasofChina.
Furthermore, it was higher in local minority groups
than in Han subjects. HHV-8 prevalence remained high
in blood donors residing in Xinjiang, but classical KS
and AIDS-related ... small study
populations have bee n carried out in China. In the
inland areas of China, HHV-8 seroprevalence in general
population was <8% [19,20]....
Báo cáo y học: "Time-dependent changes in pulmonary surfactant function and composition in acute respiratory distress syndrome due to pneumonia or aspiration" pot
... in PC and phosphatidylglycerol (PG) were
observed with a concomitant increase in the proportion of
phosphatidylserine (PS), phosphatidylinositol (PI), phos-
phatidylethanolamine (PE) and sphingomyelin ... elec-
trocardiogram, clinical laboratory tests (hematology, clin-
ical chemistry, coagulation), and pulmonary function
prior to inclusion into the study.
Study design and broncho...