Báo cáo y học: "Two-dose-level confirmatory study of the pharmacokinetics and tolerability of everolimus in Chinese patients with advanced solid tumors" pps

... Two-dose-level confirmatory study of the pharmacokinetics and tolerability of everolimus in Chinese patients with advanced solid tumors. Journal of Hematology & Oncology 2011 4:3. Xu et al. Journal of ... I, randomized, multicenter, open-label study investigated the pharmacokinetics, safe ty, and efficacy of the oral mammalian target of rapam...

Ngày tải lên: 10/08/2014, 21:23

... abuse with physical problems and finally addiction. It is certain that the physical and psychological problems that accompany the pathological relationship with alcohol increase with the quantity ... creating new clinical results and various study areas. Competing interests The authors declare that they have no competing interests. Authors' contributions GM and AD...

Ngày tải lên: 08/08/2014, 23:21

... treatment facilitated the secretion of the anti-inflammatory cytokine IL-10 over the pro-inflammatory cytokine IFN-γ, resulting in the over- all skewing (immune deviation) of the cytokine response to an anti-inflammatory ... Sprague Dawley (Indianapolis, IN, USA), and then maintained in the vivarium facility of the University of Maryland School of Medi- cine (UM...

Ngày tải lên: 09/08/2014, 10:20

... teaching reinforced confidence of staff working with the protocol. Finally, the protocol was introduced to housestaff at the start of their ICU rotation. The MDT agreed to ensure safety of the ... comfortable with a SBT of 60 min. During the SBT, the patient was continuously monitored for any signs of intolerance (Fig. 1). If the patient developed any of these...

Ngày tải lên: 12/08/2014, 18:21

... and KH carried out the data analysis and drafted the manuscript. XGY, MA, participated in the design of the study and coordination. KLW participated in the data analysis and helped to draft the ... better at detecting CTL responses [38] and different from the observation in another study on a Chinese population infected with HIV-1 Thai B [29]. In the...

Ngày tải lên: 13/08/2014, 05:22

... Azorin JM, Giudicelli S: Clozapine in the treatment of psychotic refractory depression. Br J Psychiatry 1993, 163:822-4. 9. Hrdlicka M: Combination of clozapine and maprotiline in refractory psychotic ... than standard, sec- ond and third line treatment for psychotic depression, in improving mood and psychotic symptoms', there remains much uncertainty and we would sup...

Ngày tải lên: 08/08/2014, 21:20

... 62%) and infraspinatus atrophy (volume reduction 61%, thickness reduction 70%). The difference in atrophy is remarkable. Since the infraspinatus muscle is innervated by a higher nerve branch of the ... the rel- atively elongated infraspinatus muscle. This is in line with a recent study which suggests that secondary changes in muscle fibre properties occur as a result of...

Ngày tải lên: 10/08/2014, 10:20

Ngày tải lên: 10/08/2014, 10:20

... dimerization. These studies were carried out by expressing the ligand-binding domain (LBD) of EcR and USP on two-hybrid vectors, and examining their ability to dimerize in the absence and presence of ecdysteroids. ... protein consisting of the activation domain of GAL4 and the C-terminal part of USP including a portion of the hinge region and the LBD. It wa...

Ngày tải lên: 18/03/2014, 01:20

... This substance inhibits the secretion of gastrin, cholecystokinin, secretin, glucagon, insulin, motilin and gastric acid [16] and the absorption of amino acids, glucose and fatty acids in the gastrointestinal ... observed in the majority of islets where they occur peripherally as groups of cells, and within the pancreatic islets of several marsupial species. I...

Ngày tải lên: 07/08/2014, 14:23