VASCULAR COMPLICATIONS OF DIABETES - PART 6 doc
VASCULAR COMPLICATIONS OF DIABETES - PART 6 doc
... with diabetes over the age of 30 is partly due to the difficulty in determining the precise date of onset of disease. The prevalence of retinopathy at the time of diag- nosis of type 2 diabetes ... the development of dia- betic retinopathy. The US Diabetes Control and Complications Trial (DCCT) evaluated the rates of development of microvascular complications in tw...
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VASCULAR COMPLICATIONS OF DIABETES - PART 8 doc
... 5.4 5. 5 -6 .9 ≥ 7 diabetes trend) Cause of death (n=1204) (n- 160 6) (n= 161 1) (n=81) (n= 160 ) P value All causes (n=135) Age adjusted rate/100 1 .65 (18) 2.33 (35) 3.43 (61 ) 4.35 (5) 5.92 ( 16) 40.8 Relative ... as 3- deoxyglucosone (3-DG) and methylglyoxal (MGO). 3-DG is formed by non- oxidative rearrangement and hydrolysis of Amadori adducts and from fruc- tose-3-phosphate, w...
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VASCULAR COMPLICATIONS OF DIABETES - PART 9 doc
... (% of control) 150 140 130 120 110 100 0 0 100 110 120 130 140 150 160 170 0 010 -1 1 10 -1 0 10 -9 TPA (M) 10 -8 10 -7 10 -6 n.s 10 20 Glucose (mM) Mannose 30 40 520 mmol Table 21.1 Diabetes- related ... - Retina Rat, canine ↑↑ - II, δ Aorta Rat, canine ↑↑ - Glomeruli Rat, mouse ↑↑ - , - I, - Monocytes Human NM ↑ - II ↑ = increased; NM = not...
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VASCULAR COMPLICATIONS OF DIABETES - PART 1 ppt
... 4. Vascular Diseases etiology. WK 835 V3305 2005] I. Donnelly, Richard, 1 96 0- II. Horton, Edward S. RC700.D5V375 2005 61 6.1'3 dc22 2005008488 ISBN-13: 97 8-1 -4 05 1-2 78 5-1 ISBN-10: 1-4 05 1-2 78 5 -6 A ... (%) 20 10 0 30 Cumulative incidence of ESRD (%) 20 10 0 30 Cumulative incidence of IEA (%) 20 10 0 0 8 16 24 32 40 48 56 64 0 8 16 24 32 40 48 56 64...
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VASCULAR COMPLICATIONS OF DIABETES - PART 2 pot
... scale) 10000 1000 100 10 1 0 10–14 15–19 20–24 25–29 35–39 30–34 40–44 45–49 55–59 65 69 50–54 60 64 Age (years) SECTION I • MICRO- AND MACROVASCULAR COMPLICATIONS OF DIABETES 22 CONCLUSION Risk factors for the micro- and macrovascular complications of diabetes are similar ... cohort study found a history of MI in 16. 5% of males and 9.7% of females at the time of dia...
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VASCULAR COMPLICATIONS OF DIABETES - PART 3 potx
... with diabetes. Much of our infor- mation on interventions that prevent or retard the vascular complications of diabetes are derived from either sub-group analyses of larger trials, or extrap- olation ... Cohort Study, I: all-cause mortality in patients with insulin-treated diabetes mellitus; Diabet. Med. 1999; 16: 459– 465 . SECTION I • MICRO- AND MACROVASCULAR COMPLICATIONS...
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VASCULAR COMPLICATIONS OF DIABETES - PART 4 pot
... 258– 268 . The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin dependent diabetes ... Copyright © 2005 by Blackwell Publishing Ltd SECTION I • MICRO- AND MACROVASCULAR COMPLICATIONS OF DIABETES 66 Revascularization Urgent revascularization is...
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VASCULAR COMPLICATIONS OF DIABETES - PART 5 ppsx
... In the Diabetes Control and Complications Trial (DCCT) ‘clinically detectable’ neu- ropathy was found in 39% of the participants who had type 1 diabetes. In the Epidemiology of Diabetes Complications ... VEGF expres- sion in controls. Intramuscular gene transfer of plasmid DNA encoding VEGF- 1 or VEGF-2 in the STZ-diabetic rat and alloxan diabetic rabbit results in restora- tio...
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VASCULAR COMPLICATIONS OF DIABETES - PART 7 pptx
... oedema P No. oedema P Non-proliferative Mild 172 1.7 – 152 2 .6 – 1 26 6.3 – Moderate to severe 128 20.3 <0.001 60 36. 7 <0.001 87 63 .2 <0.001 Proliferative 85 69 .7 – 26 73.1 – 35 74.3 *Percentage ... five years of diagnosis, increasing to 67 % in those with diabetes of >35 years duration. In type 2 diabetes, the corresponding prevalence rates are 2% rising to 16%...
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VASCULAR COMPLICATIONS OF DIABETES - PART 10 potx
... vessels elsewhere 145, 1 46, 163 , 164 , 165 pathogenesis 166 retinal detachment 145 6 treatment 166 –7, 167 vascular permeability factor 166 vitrectomy 168 –9 vitreous detachment 166 protein kinase C ... retinopathy 144 6, 163 –70 definitions 163 –4, 164 , 165 diagnosis/natural history 164 6, 165 disc new vessels 145, 164 epidemiology 163 iris neovascularization 164 , 165 laser...
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