VASCULAR COMPLICATIONS OF DIABETES - PART 4 pot
... therapy 3 2 1 0 4 3 P=0. 54 P=0. 14 P=0.0 34 74% risk reduction P=0.099 P=0.0052 Patients (%) 69 Years 12 15 SECTION I • MICRO- AND MACROVASCULAR COMPLICATIONS OF DIABETES 74 Retinopathy The ... 258–268. The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term c...
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... scale) 10000 1000 100 10 1 0 10– 14 15–19 20– 24 25–29 35–39 30– 34 40 44 45 49 55–59 65–69 50– 54 60– 64 Age (years) SECTION I • MICRO- AND MACROVASCULAR COMPLICATIONS OF DIABETES 22 CONCLUSION Risk factors for the micro- and ... cohort study found a history of MI in 16.5% of males and 9.7% of females at the time of diagnosis of diabetes. During a 10-year follow-up t...
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... Study, I: all-cause mortality in patients with insulin-treated diabetes mellitus; Diabet. Med. 1999; 16: 45 9 46 5. SECTION I • MICRO- AND MACROVASCULAR COMPLICATIONS OF DIABETES 44 ... HbA1 C 7.9% Patients with at least one end-point No. of patients (%) 41 (41 %) 46 (46 %) Patients without any end-point No. of patients (%) 59 (59%) 54 ( 54% ) Differences Benefit of inte...
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VASCULAR COMPLICATIONS OF DIABETES - PART 10 potx
... Ltd INDEX 233 iris neovascularization 146 , 1 64, 165 and microalbuminuria 1 34 5 microaneurysms 140 neovascular glaucoma 146 , 172 new vessels elsewhere 145 , 146 , 163, 1 64, 165 preproliferative 142 4, 142 prevalence ... oedema 142 cotton wool spots 139, 141 , 142 , 143 , 173, 1 74 deep retinal haemorrhages 144 diagnosis 147 direct ophthalmoscopy 148 disc new vessels 145 , 1 64...
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VASCULAR COMPLICATIONS OF DIABETES - PART 1 ppt
... incidence of ESRD (%) 20 10 0 30 Cumulative incidence of IEA (%) 20 10 0 0 8 16 24 32 40 48 56 64 0 8 16 24 32 40 48 56 64 0 8 16 24 32 Years after diagnosis of diabetes 40 48 56 64 Standard ... 4. Vascular Diseases etiology. WK 835 V3305 2005] I. Donnelly, Richard, 196 0- II. Horton, Edward S. RC700.D5V375 2005 616.1'3 dc22 200500 848 8 ISBN-13: 97 8-1 -4 0...
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VASCULAR COMPLICATIONS OF DIABETES - PART 5 ppsx
... In the Diabetes Control and Complications Trial (DCCT) ‘clinically detectable’ neu- ropathy was found in 39% of the participants who had type 1 diabetes. In the Epidemiology of Diabetes Complications ... 21: 822–827. Study 3 (III-172) 36 44 D’Hemercourt et al. Wounds 1998; 10: 69–75. Study 4 (III-250) 32 36 Smiell et al. Wound Rep Regen 1999; 7: 335– 346 . Study 5 (IIIb-1 34)...
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VASCULAR COMPLICATIONS OF DIABETES - PART 6 doc
... with diabetes over the age of 30 is partly due to the difficulty in determining the precise date of onset of disease. The prevalence of retinopathy at the time of diag- nosis of type 2 diabetes ... the development of dia- betic retinopathy. The US Diabetes Control and Complications Trial (DCCT) evaluated the rates of development of microvascular complications in tw...
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VASCULAR COMPLICATIONS OF DIABETES - PART 7 pptx
... 19 84; 91: 146 4– 147 4. Relationship of Diabetic Retinopathy with Macular Oedema* and Duration of Diabetes (Wisconsin, HAS-1, 198 0-8 2) Younger onset Older onset Duration 10+ years Duration 0– 14 ... DISORDERS 152 Fig. 17.1 Frequency of macular oedema by duration of diabetes in years for insulin- taking early onset persons. Ophthalmology 19 84; 91: 146 4– 147 4. Per cent wi...
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VASCULAR COMPLICATIONS OF DIABETES - PART 8 doc
... as 3- deoxyglucosone (3-DG) and methylglyoxal (MGO). 3-DG is formed by non- oxidative rearrangement and hydrolysis of Amadori adducts and from fruc- tose-3-phosphate, which is a product of the ... HYPERGLYCAEMIA INDUCED VASCULAR DYSFUNCTION 180 Age-adjusted death rates: all-cause, CVD, IHD & non-cardiovascular Glycated haemoglobin (%) Self- χ 2 reported (linear < 5 5 5 .4 5....
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VASCULAR COMPLICATIONS OF DIABETES - PART 9 doc
... (% of control) 150 140 130 120 110 100 0 0 100 110 120 130 140 150 160 170 0 010 -1 1 10 -1 0 10 -9 TPA (M) 10 -8 10 -7 10 -6 n.s 10 20 Glucose (mM) Mannose 30 40 520 mmol Table 21.1 Diabetes- related ... 1991; 87: 1 643 –1 648 . Williams B, Schrier RW. Characterization of glucose-induced in situ protein kinase C activi- ty in cultured vascular smooth muscle...
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