... 22 2IC50values 21 4nephropathy 21 6–17, 21 8–19peripheral neuropathy 22 4retinopathy 21 3–17, 21 5–17, 22 1–4, 22 2, 22 3structure 21 4Rydel-Seiffer tuning fork 97S San Luis Valley Diabetes Study ... StaurosporinePKC-α 360 45PKC-β14.7 23 PKC-β 2 5.9 19PKC-γ 300 110PKC-δ 25 0 28 PKC-ε 600 18PKC-ζ >105>1.5 × 103PKC-η 52 5Cyclic AMP kinase >105100Ca 2+ -calmodulin kinase 8 × 1034Casein ... 28 retinopathy 129 , 134age-adjusted death rate 180ALADIN-II study 87albumin-creatinine ratio 25 albuminuria 22 , 24 Albustix 24 , 25 alcohol dependency 51, 52 aldose reductase 76, 85, 86, 124 ,...