VASCULAR COMPLICATIONS OF DIABETES - PART 2 pot

... type 2 diabetes in the inci- dence of microvascular complications in relation to rising HbA1 C . In the UKPDS the risk of each of the microvascular and macrovascular complications of type 2 diabetes ... scale) 10000 1000 100 10 1 0 10–14 15–19 20 24 25 29 35–39 30–34 40–44 45–49 55–59 65–69 50–54 60–64 Age (years) SECTION I • MICRO- AND MACROVASCULAR COMPLICATIONS...

Ngày tải lên: 10/08/2014, 18:21

... Lancet 20 00; 355: 25 3 25 9. Cumulative mortality Kaplan-Meier rates 0.08 0.10 0. 12 0.06 0. 02 0.04 0.00 0 500 Days of follow-up Ramipril Placebo RRR = 37% (2 1-5 1) P=0.0001 1000 1500 20 00 CHAPTER ... 2- ADR, 2- adrenergic receptor; EP-R, prostaglandin E receptor; VIP-R, vasoactive intestinal peptide receptor; NO, nitric oxide. NO VIP Nitrergic Smooth muscle Vipergic VIP-R...

Ngày tải lên: 10/08/2014, 18:21

... people with diabetes – MICRO-HOPE. Lancet 20 00; 355: 25 3 25 9. 0.16 Myocardial infarction Stroke Cardiovascular death 0. 12 Kaplan-M 0 08 0.04 0 0 500 1000 20 001500 0.08 0.06 Kaplan-M 0 04 0. 02 0 0 500 ... different years of the study. NEJM 1993; 329 : 977–986. 40 30 20 0 10 60 Conventional Intensive P<0.001 50 0 Conventional Intensive 123 375 3 42 4 Year of study 5 22...

Ngày tải lên: 10/08/2014, 18:21

... 22 2 IC 50 values 21 4 nephropathy 21 6–17, 21 8–19 peripheral neuropathy 22 4 retinopathy 21 3–17, 21 5–17, 22 1–4, 22 2, 22 3 structure 21 4 Rydel-Seiffer tuning fork 97 S San Luis Valley Diabetes Study ... Staurosporine PKC-α 360 45 PKC-β 1 4.7 23 PKC-β 2 5.9 19 PKC-γ 300 110 PKC-δ 25 0 28 PKC-ε 600 18 PKC-ζ >10 5 >1.5 × 10 3 PKC-η 52 5 Cyclic AMP kinase >10...

Ngày tải lên: 10/08/2014, 18:21

... 4. Vascular Diseases etiology. WK 835 V3305 20 05] I. Donnelly, Richard, 196 0- II. Horton, Edward S. RC700.D5V375 20 05 616.1'3 dc 22 2005008488 ISBN-13: 97 8-1 -4 05 1 -2 78 5-1 ISBN-10: 1-4 05 1 -2 78 5-6 A ... bibliographical references and index. ISBN-13: 97 8-1 -4 05 1 -2 78 5-1 (alk. paper) ISBN-10: 1-4 05 1 -2 78 5-6 (alk. paper) 1. Diabetic angio...

Ngày tải lên: 10/08/2014, 18:21

... μg/g 100 μg/g Study 1 (II-118) 25 48 Steed et al. J Vasc Surg 1995; 21 : 71–78. Study 2 (III-3 82) 35 36 50 Wieman et al. Diabetes Care 1998; 21 : 822 – 827 . Study 3 (III-1 72) 36 44 D’Hemercourt et ... In the Diabetes Control and Complications Trial (DCCT) ‘clinically detectable’ neu- ropathy was found in 39% of the participants who had type 1 diabetes. In the Epidemiology of...

Ngày tải lên: 10/08/2014, 18:21

... onset* None 8 32 95.3 2. 8 1.4 0.5 Mild 26 26 .9 42. 3 15.4 15.4 Moderate 10 10.0 10.0 30.0 50.0 Blind 20 0 0 0 100.0 Older-onset, taking insulin † None 423 83.9 10.6 4.3 1 .2 Mild 27 29 .6 22 .6 40.7 7.4 Moderate ... with diabetes over the age of 30 is partly due to the difficulty in determining the precise date of onset of disease. The prevalence of retinopathy at the tim...

Ngày tải lên: 10/08/2014, 18:21

... oedema P No. oedema P Non-proliferative Mild 1 72 1.7 – 1 52 2.6 – 126 6.3 – Moderate to severe 128 20 .3 <0.001 60 36.7 <0.001 87 63 .2 <0.001 Proliferative 85 69.7 – 26 73.1 – 35 74.3 *Percentage ... Publishing Ltd Fig. 17 .2 Frequency of macular oedema by duration of diabetes for insulin- and non-insulin-taking older onset persons. The Wisconsin Epidemiologic Study o...

Ngày tải lên: 10/08/2014, 18:21

... 145/10,631 21 ,963 4.5 (2. 9–7.0) 7 to <8 197/10,6 92 23,417 5.8 (3.8–8.9) 8 to <9 181/9 ,23 8 20 ,808 6.3 (4.1–9.7) 9 to <10 1 72/ 7,354 16,576 8.3 (5.5– 12. 6) ≥ 10 24 0/10,943 23 ,594 9 .2 (6 .2 13.8) SECTION ... the catabolism of ketone bodies and threonine. 1.3 1.1 1.0 0 1.00 3 1 .21 2 1.13 1 1.07 0 1.00 15 1.16 10 1.10 20 1 .21 5 1.05 1 .2 2-hour-PG mmol/L SBP mm/...

Ngày tải lên: 10/08/2014, 18:21

... (% of control) 150 140 130 120 110 100 0 0 100 110 120 130 140 150 160 170 0 010 -1 1 10 -1 0 10 -9 TPA (M) 10 -8 10 -7 10 -6 n.s 10 20 Glucose (mM) Mannose 30 40 520 mmol Table 21 .1 Diabetes- related ... rats in vivo. Diabetes 1999; 48: 20 52 20 58. Huang Q & Yuan Y. Interaction of PKC and NOS in signal transduction of microvascular hyperpermeabili...

Ngày tải lên: 10/08/2014, 18:21