Stem Cells in Endocrinology - part 6 ppsx

... insulin-expressing cells gradu- ally increased. To characterize the insulin-producing cells further, they mea- sured insulin secretion from 2 0- to 22-day-old EBs and 2 2- and 31-day-old, high-density ... Berna G, Leon-Quinto T, Reig JA, Martin F. Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice. Dia- betes...

Ngày tải lên: 10/08/2014, 18:21

... 1.0 staining. In the latter procedure, negative staining controls were digested with chondroitinase-ABC or chondroitinase-AC prior to staining (6, 7, 86, 87). Chapter 5 / Murine Embryonic Stem Cells ... CD 36, CD38, CD41, CD42b, CD45, CD49d, CD55, CD57, CD59, CD61, CD62E, CD65, CD66e, CD68, CD69, CD71, CD79, CD83, CD95, CD105, CD117, CD123, CD135, CD 166 , Glycophorin-A, HLA-DRII, FMC-7...

Ngày tải lên: 10/08/2014, 18:21

... production of robust glucose-responsive insulin- secreting cells. Aside from the question of whether ES cell-derived nestin-positive cells can differentiate into insulin-secreting cells, there has been ... SSEA-1 in mouse and SSEA-3 and SSEA-4 in human, and well as tumor-recognition antigens TRA- 1 -6 0 and TRA- 1-8 1 in human. In the uncommitted state both mouse and human ES...

Ngày tải lên: 10/08/2014, 18:21

... CD135, CD 166 , Glycophorin-A, MHC-I, human leukocyte antigen (HLA)-DRII, FMC-7, Annexin-V, or LIN cell-surface markers. Other investiga- tors have found similar results for pluripotent stem cells ... layers in vitro. This character- istic sets them apart from germ layer lineage stem cells and progenitor cells. Pluripotent stem cells are responsive to any lineage-induction age...

Ngày tải lên: 10/08/2014, 18:21

... CA, Lin JC, Zulewski H, Habener JF. Insulinotropic hormone glucagon- like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin- producing cells. Endocrinology ... Similarities in the sequence of early histological changes induced in the liver of the rat by ethionine, 2-acetylaminofluorene and 3′-methyl-4-dimethyl-aminoazobenzene. Cancer Res 19 56;...

Ngày tải lên: 10/08/2014, 18:21

... Concordance for type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus in a population-based cohort of twins in Finland Diabetologia 1993;35:1 060 –1 067 . 40. Kumar D, Gemayel ... diabetes is characterized by insulin deficiency secondary to progres- sive T-cell-mediated destruction of insulin-producing pancreatic β cells within the islets of Langerhans. Clinica...

Ngày tải lên: 10/08/2014, 18:21

... expression, 77, 142, 166 , 168 , 170, 175 α-fetoprotein, 166 Transcription factors, 77, 142, 1 76 HNF-4, 166 , 175 Regeneration, 165 , 167 , 169 –172 Therapy, 12, 141–142, 165 , 168 – 169 , 171–175, 235 M Matrix ... of, 2 56 Autoimmunity and, 2 26, 230, 250, 253 Embryonic stem cells in, 134, 135 HoxB4-induced ES cells, 135 Food and Drug Administration clinical guidelines, 248 Umbil...

Ngày tải lên: 10/08/2014, 18:21

... registered in U.S. hospitals is not confined to the industrialized world or to bacterial infections. In some settings, a substantial minority of patients with TB are infected with strains resistant ... case-finding relies on the availability of health care services, which is uneven in settings where TB is most prevalent. Third, patients with multidrug-resistant (MDR) TB are by defin...

Ngày tải lên: 06/07/2014, 08:20

Ngày tải lên: 09/08/2014, 22:21