Endocrinology Basic and Clinical Principles - part 2 pdf

... interleukin -2 (IL -2 ) , IL-3, IL-4, IL-5, IL-6, IL-7, IL-9, IL-11, IL- 12, erythropoietin, granulocyte macrophage colony-stimulating factor, interferon-β (IFN-β), IFN-γ, and CNTF. Many of these receptors are ... Ligand-Induced Binding of Tyrosine Kinases (GH, PRL) The GH and PRL receptors belong to a large super- family of receptors that include the cytokine receptors for interleukin -...

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... variety of cytokines and growth fac- tors (including interleukin-1α [IL-α] and IL-β, tumor necrosis factor-α [TNF-α], and transforming growth factor [TGF-β], as well as ANP and BNP) can stimulate CNP ... designated the GC-A and GC-B receptors and are alternatively called natri- uretic peptide receptor-A (NPR-A) and NPR-B. A third receptor subtype, called the clearance receptor o...

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... Michael Conn.— 2nd ed. p. cm. Includes bibliographical references and index. ISBN 1-5 8 82 9-4 2 7-7 (alk. paper) eISBN 1-5 925 9-8 2 9-3 1. Endocrinology. 2. Hormones. 3. Endocrine glands—Diseases. ... Service is: [ 1-5 8 82 9-4 2 7-7 /05 $30]. Printed in the United States of America. 10 9 8 7 6 5 4 3 2 1 Library of Congress Cataloging-in-Publication Data...

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... hormonal nature of 24 ,25 -dihydroxyvitamin D 3 (24 ,25 [OH] 2 D 3 ), once thought to represent merely the inactivation product of precursor 25 (OH) 2 D 3 . Acute effects of 24 ,25 (OH) 2 D 3 have been ... Prostaglandins and Leukotrienes 93 93 From: Endocrinology: Basic and Clinical Principles, Second Edition (S. Melmed and P. M. Conn, eds.) © Humana Press Inc., Totowa,...

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... corpus luteum, which secretes progesterone, 20 α-hydroxy- 4-pregnen-3-one, pregnenolone, 17β-hydroxypro- gesterone, 4-androstenedione, estrone, and estradiol. In bovine and ovine corpora lutea, although ... steroidogenesis are exemplified, on the one hand, by the bovine corpus luteum, which secretes progesterone, 20 β-hydroxy-4-pregnen-3-one, and preg- nenolone, and on the other han...

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... β-subunits α, β-subunits Protein length (kDa) ACTH: 4.5 22 23 28 34 28 .5 Amino acid no. 26 6 (ACTH-39) 191 199 21 1 21 0 20 4 Normal range ACTH, 4 22 pmol/L <0.5 µg/L b M < 15; F < 20 µg/L 0.1–5 ... the gene, including the 39-amino-acid adrenocorticotropin (ACTH), α-mel- anocyte-stimulating hormone (α-MSH), β-MSH,β-lipo- tropin (β-LPH), β-endorphin, and corticotropin-like...

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... (BMI >38 kg/m 2 ). PPAR-γ exists as two isoforms, PPAR- -1 and -2 , derived by alternate pro- moter usage, and much interest has focused on a poly- morphism in the PPAR- -2 gene that is exclusively expressed ... hypercalce- mia results. Some tumors such as lymphomas cause hypercalcemia through the presence of a 2 5-( OH )- vitamin D-1αa-hydroxylase enzyme that converts...

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... the C 23 calcitroic acid (1[OH ] -2 4 ,25 ,26 ,2 7- tetranor -2 3 -COOH-D) or 1 ,25 (OH) 2 D -2 6 ,23 -lactone. 24 ,25 (OH) 2 D can also be metabolized by two pathways leading to either 25 ,26 ,27 -trinor -2 4 -COOH-D ... affinity for 25 (OH)D, 24 ,25 (OH) 2 D, and 25 ,26 (OH) 2 D than for vitamin D or 1 ,25 (OH) 2 D. This facilitates partitioning of vitamin D in lipid...

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... Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu Ang II Asp-Arg-Val-Tyr-Ile-His-Pro-Phe Ang III Arg-Val-Tyr-Ile-His-Pro-Phe Ang IV Val-Tyr-Ile-His-Pro-Phe Ang 1-7 Asp-Arg-Val-Tyr-Ile-His-Pro Chapter 24 ... = peptide YY; α-MSH = α-melanocyte- stimulating hormone; CCK = cholecystokinin; CART = cocaine- and amphetamine-regulated transcript; GLP-1 (7–36) = glucagon- like peptid -2 ( 7-3 6); PP = p...

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... detection and postnatal diagnosis, 22 7 desmopressin trial, 22 5 direct test, 22 5 indirect test, 22 5 overview, 22 4, 22 5 recommendations, 22 7 pregnancy, 22 4 renal water excretion, 22 0 treatment, 22 8 Diabetes ... forms, 22 0 hypernatremia and hypopdipsia syndrome, 22 1, 22 2 rare forms, 22 0, 22 1 magnetic resonance imaging, 22 7 nephrogenic diabetes insipidus, acqui...

Ngày tải lên: 10/08/2014, 18:21