Endocrinology Basic and Clinical Principles - part 1 ppsx
Endocrinology Basic and Clinical Principles - part 1 ppsx
... references and index. ISBN 1- 5 882 9-4 2 7-7 (alk. paper) eISBN 1- 5 925 9-8 2 9-3 1. Endocrinology. 2. Hormones. 3. Endocrine glands—Diseases. I. Melmed, Shlomo. II. Conn, P. Michael. QP187.E555 2005 612 .4—dc22 ... Service is: [ 1- 5 882 9-4 2 7-7 /05 $30]. Printed in the United States of America. 10 9 8 7 6 5 4 3 2 1 Library of Congress Cataloging-in-Publication...
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Endocrinology Basic and Clinical Principles - part 7 ppsx
... acid (1[ OH ]-2 4,25,26,2 7- tetranor-23-COOH-D) or 1, 25(OH) 2 D-26,23-lactone. 24,25(OH) 2 D can also be metabolized by two pathways leading to either 25,26,27-trinor-24-COOH-D or 24, 25,26,27-tetranor-23-COOH-D. 2 .1. 4. ... alternative 5´ UTRs, carboxyl-terminal peptides, and 3´ UTRs may also be present, depending on the species. The PTH and PTHrP genes map to chromosome 11 p15...
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Endocrinology Basic and Clinical Principles - part 10 ppsx
... challenge response, 11 5 impairment in immune-mediated diseases, 11 8, 11 9 overview, 60, 11 4 stress response, 60, 61, 11 4, 11 5 Hypothalamic-pituitary-gonadal (HPG) axis, see also specific hormones, female ... characteristics, 16 6 male sexual behavior, 15 3 15 5 maternal behavior, 14 9, 15 0 mustelids, delayed implantation, 16 8, 16 9 pelage growth cycle, 16 7, 16 neuroendo...
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Endocrinology Basic and Clinical Principles - part 2 pdf
... PRL) The GH and PRL receptors belong to a large super- family of receptors that include the cytokine receptors for interleukin-2 (IL-2), IL-3, IL-4, IL-5, IL-6, IL-7, IL-9, IL -1 1 , IL -1 2 , erythropoietin, ... colony-stimulating factor, interferon-β (IFN-β), IFN-γ, and CNTF. Many of these receptors are heterodimers consisting of an α-ligand-binding subunit and a β-signaling subunit....
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Endocrinology Basic and Clinical Principles - part 3 pot
... both an IGF -1 - dependent and -independent manner). The potential importance of the IGF system, and particularly the IGF-1R, in cancer has led to an intense effort to find blockers of IGF-1R function ... metabolite. Chapter 8 / Neuroendocrine–Immune Interface 11 3 11 3 From: Endocrinology: Basic and Clinical Principles, Second Edition (S. Melmed and P. M. Conn, eds.) © Humana...
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Endocrinology Basic and Clinical Principles - part 4 pptx
... stimulates an increase in ppET -1 , which is enzymatically cleaved to form big ET -1 . The big ET -1 is acted on by intracellular ECE-1a to form ET -1 , which is then secreted. Big ET -1 can also be secreted from ... corpus luteum, which secretes progesterone, 20α-hydroxy- 4-pregnen-3-one, pregnenolone, 17 β-hydroxypro- gesterone, 4-androstenedione, estrone, and estradiol. In bovine and...
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Endocrinology Basic and Clinical Principles - part 5 pptx
... anterior pituitar- ies. The structure of GnRH was elucidated in 19 71. The decapeptide pyroGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg- Pro-Gly-amide was named luteinizing hormone-releas- ing hormone (LHRH). ... the gene, including the 39-amino-acid adrenocorticotropin (ACTH), α-mel- anocyte-stimulating hormone (α-MSH), β-MSH,β-lipo- tropin (β-LPH), β-endorphin, and corticotropin-like intermediate lob...
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Endocrinology Basic and Clinical Principles - part 6 pps
... (BMI >38 kg/m 2 ). PPAR-γ exists as two isoforms, PPAR- -1 and -2 , derived by alternate pro- moter usage, and much interest has focused on a poly- morphism in the PPAR- -2 gene that is exclusively expressed ... failure. Kidney Int 19 86;29 :11 88 11 96. Burbach JP, Luckman SM, Murphy D, Gainer H. Gene regulation in the magnocellular hypothalamo-neurohypophysial system. Physiol...
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Endocrinology Basic and Clinical Principles - part 8 pdf
... bringing substrate proteins to the IR. Tyrosine residues 11 46, 11 50, and 11 51 are essential for tyrosine kinase activ- ity. NPEY motif (Asn-Pro-Glu-Tyr) at the juxtamem- brane region is important for substrate ... variety of cytokines and growth fac- tors (including interleukin -1 [IL-α] and IL-β, tumor necrosis factor-α [TNF-α], and transforming growth factor [TGF-β], as well...
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Endocrinology Basic and Clinical Principles - part 9 pot
... Asp-Arg-Val-Tyr-Ile-His-Pro-Phe Ang III Arg-Val-Tyr-Ile-His-Pro-Phe Ang IV Val-Tyr-Ile-His-Pro-Phe Ang 1- 7 Asp-Arg-Val-Tyr-Ile-His-Pro Chapter 24 / Reproduction and Fertility 373 maturation, fertilization, ... functional sig- nificance of the tissue RAS in cardiovascular control. Table 1 Angiotensin Peptides Peptide Sequence Ang I Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu Ang II Asp-Arg-V...
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