Endocrinology Basic and Clinical Principles - part 1 ppsx
Endocrinology Basic and Clinical Principles - part 1 ppsx
... references and index.
ISBN 1- 5 882 9-4 2 7-7 (alk. paper) eISBN 1- 5 925 9-8 2 9-3
1. Endocrinology. 2. Hormones. 3. Endocrine glands—Diseases. I. Melmed, Shlomo. II. Conn, P. Michael.
QP187.E555 2005
612 .4—dc22 ... Service is: [ 1- 5 882 9-4 2 7-7 /05 $30].
Printed in the United States of America. 10 9 8 7 6 5 4 3 2 1
Library of Congress Cataloging-in-Publication...
Endocrinology Basic and Clinical Principles - part 7 ppsx
... acid (1[ OH ]-2 4,25,26,2 7-
tetranor-23-COOH-D) or 1, 25(OH)
2
D-26,23-lactone.
24,25(OH)
2
D can also be metabolized by two pathways
leading to either 25,26,27-trinor-24-COOH-D or 24,
25,26,27-tetranor-23-COOH-D.
2 .1. 4. ... alternative 5´ UTRs, carboxyl-terminal
peptides, and 3´ UTRs may also be present, depending
on the species.
The PTH and PTHrP genes map to chromosome
11 p15...
Endocrinology Basic and Clinical Principles - part 10 ppsx
... challenge response, 11 5
impairment in immune-mediated diseases, 11 8, 11 9
overview, 60, 11 4
stress response, 60, 61, 11 4, 11 5
Hypothalamic-pituitary-gonadal (HPG) axis, see also
specific hormones,
female ... characteristics, 16 6
male sexual behavior, 15 3 15 5
maternal behavior, 14 9, 15 0
mustelids,
delayed implantation, 16 8, 16 9
pelage growth cycle, 16 7, 16
neuroendo...
Endocrinology Basic and Clinical Principles - part 2 pdf
... PRL)
The GH and PRL receptors belong to a large super-
family of receptors that include the cytokine receptors
for interleukin-2 (IL-2), IL-3, IL-4, IL-5, IL-6, IL-7,
IL-9, IL -1 1 , IL -1 2 , erythropoietin, ... colony-stimulating factor, interferon-β
(IFN-β), IFN-γ, and CNTF. Many of these receptors
are heterodimers consisting of an α-ligand-binding
subunit and a β-signaling subunit....
Endocrinology Basic and Clinical Principles - part 3 pot
... both an IGF -1 - dependent
and -independent manner).
The potential importance of the IGF system, and
particularly the IGF-1R, in cancer has led to an intense
effort to find blockers of IGF-1R function ... metabolite.
Chapter 8 / Neuroendocrine–Immune Interface 11 3
11 3
From: Endocrinology: Basic and Clinical Principles, Second Edition
(S. Melmed and P. M. Conn, eds.) © Humana...
Endocrinology Basic and Clinical Principles - part 4 pptx
... stimulates an increase in ppET -1 , which is enzymatically cleaved
to form big ET -1 . The big ET -1 is acted on by intracellular ECE-1a to form ET -1 , which is then secreted. Big ET -1 can also be secreted
from ... corpus
luteum, which secretes progesterone, 20α-hydroxy-
4-pregnen-3-one, pregnenolone, 17 β-hydroxypro-
gesterone, 4-androstenedione, estrone, and estradiol. In
bovine and...
Endocrinology Basic and Clinical Principles - part 5 pptx
... anterior pituitar-
ies. The structure of GnRH was elucidated in 19 71. The
decapeptide pyroGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-
Pro-Gly-amide was named luteinizing hormone-releas-
ing hormone (LHRH). ... the gene, including the
39-amino-acid adrenocorticotropin (ACTH), α-mel-
anocyte-stimulating hormone (α-MSH), β-MSH,β-lipo-
tropin (β-LPH), β-endorphin, and corticotropin-like
intermediate lob...
Endocrinology Basic and Clinical Principles - part 6 pps
... (BMI >38 kg/m
2
). PPAR-γ exists as two
isoforms, PPAR- -1 and -2 , derived by alternate pro-
moter usage, and much interest has focused on a poly-
morphism in the PPAR- -2 gene that is exclusively
expressed ... failure. Kidney
Int 19 86;29 :11 88 11 96.
Burbach JP, Luckman SM, Murphy D, Gainer H. Gene regulation in
the magnocellular hypothalamo-neurohypophysial system.
Physiol...
Endocrinology Basic and Clinical Principles - part 8 pdf
... bringing
substrate proteins to the IR. Tyrosine residues 11 46,
11 50, and 11 51 are essential for tyrosine kinase activ-
ity. NPEY motif (Asn-Pro-Glu-Tyr) at the juxtamem-
brane region is important for substrate ... variety of cytokines and growth fac-
tors (including interleukin -1 [IL-α] and IL-β, tumor
necrosis factor-α [TNF-α], and transforming growth
factor [TGF-β], as well...
Endocrinology Basic and Clinical Principles - part 9 pot
... Asp-Arg-Val-Tyr-Ile-His-Pro-Phe
Ang III Arg-Val-Tyr-Ile-His-Pro-Phe
Ang IV Val-Tyr-Ile-His-Pro-Phe
Ang 1- 7 Asp-Arg-Val-Tyr-Ile-His-Pro
Chapter 24 / Reproduction and Fertility 373
maturation, fertilization, ... functional sig-
nificance of the tissue RAS in cardiovascular control.
Table 1
Angiotensin Peptides
Peptide Sequence
Ang I Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu
Ang II Asp-Arg-V...