Basic medical endocrinology - part 7 pot
... 329 0.0 10 20 30 40 50 60 70 80 90 100 prenatal -9 months til birth juvenile 1-1 2 years infantile birth -1 year adolescence ages 1 0-1 4 (girls) 1 2-1 6 (boys) stagepercent of adult height sex steroids insulinIGFs ... 1.15 Day 1 80 10–12 120 120 5.4 1.15 Day 3 70 8 150 110 — 0 .70 Day 5 70 7 150 110 6.1 0.60 a Values for GH are from Ho et al., J. Clin. Invest. 81, 968– 9...
Ngày tải lên: 10/08/2014, 18:21
... through the IGF-I receptor. The IGF-II receptor is structurally unrelated to the IGF-I receptor and binds IGF-II with a very much higher affinity than IGF-I . It consists of a single membrane-spanning ... Curiously, the IGF-II receptor is identical to the mannose- 6- phosphate receptor that binds mannose-6-phosphate groups on newly synthesized lysosomal enzymes and transfers them from the t...
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... vomiting or confusion ACUTE MEDICAL EMERGENCIES: THE PRACTICAL APPROACH 300 20-AcuteMed-20-cpp 28/9/2000 4:43 pm Page 300 PART V SPECIAL CIRCUMSTANCES 20-AcuteMed-20-cpp 28/9/2000 4:43 pm Page ... hepatic encephalo- pathy ORGAN FAILURE 2 87 19-AcuteMed-19-cpp 28/9/2000 4:41 pm Page 2 87 Renal A “cold diuresis” occurs, due to increased central blood volume (peripheral vasocon- striction...
Ngày tải lên: 10/08/2014, 18:21
Basic medical endocrinology - part 1 ppsx
... Introduction O CH 2 O - P=O O O CH 3 O HN N O Thymine O CH 2 O - P=O O O O O CH 2 O - P=O O O O O CH 2 O - P=O O O O O CH 2 O - P=O O O O O O N N N N NH 2 Adenine O HN N N N H 2 N Guanine N NH 2 O N Cytosine O - ... with cross-talk among the various G-protein receptor-mediated signaling pathways, or among the various tyrosine phosphorylation-dependent pathways, and amo...
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Basic medical endocrinology - part 2 doc
... Hormones 47 H-Ab H-Ab H-Ab H-Ab H-Ab H-Ab Ab Ab Ab Ab H H H H H H H H H + H H-Ab H-Ab H-Ab H-Ab H-Ab H-Ab Ab Ab Ab Ab H H H H H H H H H + H H H H H H H H-Ab H-Ab H-Ab H-Ab H-Ab H-Ab H-Ab Ab Ab Ab Ab H H H H H H + H Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab A 10 0 101 0 20 40 60 80 100 550330 hormone ... into α-melanocyte-stimulating hormone (α-MSH) and the corticotropin-like intermediate...
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Basic medical endocrinology - part 3 docx
... Glands HO C=O CH 3 OH HO C=O CH 3 HO O P450c17P450c 17 17 a-pregnenolone dehydroepiandrosteronepregnenolone O C=O CH 3 OH O C=O CH 3 O O P450c17P450c 17 17 a-progesterone androstenedioneprogesterone O C=O CH 2 OH OH O OO O O HO ... Glands C=O CH 2 OH CH 2 OH HO HO - - - cortisol (active) O C=O O cortisone (inactive) HSD I HSD II HSD I O HO - - - Figure 5 The cortisol/...
Ngày tải lên: 10/08/2014, 18:21
Basic medical endocrinology - part 4 docx
... interleukins (IL-1 through IL-18), tumor necrosis factor (TNF), the interferons (IFN-α ,- , and - ), colony-stimulating factor (CSF), granulocyte/macrophage colony-stimulating fac- tor (GM-CSF), transforming ... cell s glicentin IP2GLP-1 GLP-2 3 3-6 1 Figure 2 Cell-specific posttranslational processing of preproglucagon. GRPP, Glicentin-related pancreatic peptide; GLP-1, glucagon-like p...
Ngày tải lên: 10/08/2014, 18:21
Basic medical endocrinology - part 5 pps
... of 194 Chapter 5. The Pancreatic Islets -S-S- -S-S -S-S- COOH COOH insulin binding domain tyrosine kinase domain membane α-subunits β-subunits NH 2 NH 2 - Figure 18 Model of the insulin receptor. Regulation ... hepatic action to increase Reinforcement 209 Insulin 191 glycogen glucose-1-P I glucose-6-Pglucose II fructose-6-P fructose-1,6-P III hexose monophosphate shunt PEP pyruvate IV a...
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Basic medical endocrinology - part 6 ppsx
... blood and express the same G-protein-coupled calcium-sensing 278 Chapter 8. Hormonal Regulation of Calcium Metabolism component of the recovery phase.Thirst and salt-conserving mechanisms would be ... stored in membrane- bound granules, and secreted by exocytosis from cardiac atrial myocytes.ANF is a 28-amino-acid peptide that corresponds to the carboxyl terminus of a 126-amino- acid prohorm...
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Basic medical endocrinology - part 9 pptx
... Cycle HO C=O CH 3 C=O CH 3 C=O CH 3 pregnenolone C=O CH 3 progesterone O O OH HO 17 α-pregnenolone 17 α-pregesterone 3βHSD 3βHSD 3βHSD 17 HSD 17 HSD P450c 17 P450c 17 = O androstenedione O P450scc P450c 17 HO = O dehydroepiandrosterone testosterone O H O H O = O HO HO estrone ... binding protein; StAR, steroid acute regulatory protein; P450c 17, 17 -dehydrogenase/lyase; 3βDH, 3β-hydro...
Ngày tải lên: 10/08/2014, 18:21