Basic medical endocrinology - part 6 ppsx
Basic medical endocrinology - part 6 ppsx
... stored in membrane- bound granules, and secreted by exocytosis from cardiac atrial myocytes.ANF is a 28-amino-acid peptide that corresponds to the carboxyl terminus of a 1 2 6- amino- acid prohormone, ... Berl,T., In “The Kidney,” 5th Ed., p. 881, Saunders, Philadelphia, 19 96, with permission.) N -1 0 -1 5 -2 0 +10 +20 +15 10 8 6 4 2 0 260 270 280 290 300 310 320 330 340 plasma o...
Ngày tải lên: 10/08/2014, 18:21
Basic medical endocrinology - part 1 ppsx
... Introduction O CH 2 O - P=O O O CH 3 O HN N O Thymine O CH 2 O - P=O O O O O CH 2 O - P=O O O O O CH 2 O - P=O O O O O CH 2 O - P=O O O O O O N N N N NH 2 Adenine O HN N N N H 2 N Guanine N NH 2 O N Cytosine O - ... with cross-talk among the various G-protein receptor-mediated signaling pathways, or among the various tyrosine phosphorylation-dependent pathways, and amo...
Ngày tải lên: 10/08/2014, 18:21
Basic medical endocrinology - part 2 doc
... 47 H-Ab H-Ab H-Ab H-Ab H-Ab H-Ab Ab Ab Ab Ab H H H H H H H H H + H H-Ab H-Ab H-Ab H-Ab H-Ab H-Ab Ab Ab Ab Ab H H H H H H H H H + H H H H H H H H-Ab H-Ab H-Ab H-Ab H-Ab H-Ab H-Ab Ab Ab Ab Ab H H H H H H + H Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab A 10 0 101 0 20 40 60 80 100 550330 hormone ... into α-melanocyte-stimulating hormone (α-MSH) and the corticotropin-like intermediate lobe pep...
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Basic medical endocrinology - part 3 docx
... Glands C=O CH 2 OH CH 2 OH HO HO - - - cortisol (active) O C=O O cortisone (inactive) HSD I HSD II HSD I O HO - - - Figure 5 The cortisol/cortisone shuttle. Two isoenzymes of 11-hyrdoxysteroid dehydrogenase (HSD ... receptors Ca 2+ Ca 2+ TRHR TRH PIP2 TSH-α mRNA TSH-β mRNA TRHR TRHR (-) (-) preTSH secretory vesicles TSH golgi apparatus processing (+) (+) (+) nucleus...
Ngày tải lên: 10/08/2014, 18:21
Basic medical endocrinology - part 4 docx
... fructose-1, 6- bisphosphate, is formed from fructose -6 - phosphate by the action of an unusual bifunctional enzyme that catalyzes either phosphorylation of fructose -6 - phosphate to fructose-2 , 6- bisphosphate ... cell s glicentin IP2GLP-1 GLP-2 3 3 -6 1 Figure 2 Cell-specific posttranslational processing of preproglucagon. GRPP, Glicentin-related pancreatic peptide; GLP-1, glucagon-like...
Ngày tải lên: 10/08/2014, 18:21
Basic medical endocrinology - part 5 pps
... hepatic action to increase Reinforcement 209 Insulin 191 glycogen glucose-1-P I glucose -6 - Pglucose II fructose -6 - P fructose-1 , 6- P III hexose monophosphate shunt PEP pyruvate IV acetyl CoA fatty ... of 194 Chapter 5. The Pancreatic Islets -S-S- -S-S -S-S- COOH COOH insulin binding domain tyrosine kinase domain membane α-subunits β-subunits NH 2 NH 2 - Figure 18 Model of the insu...
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Basic medical endocrinology - part 7 pot
... 1511–1515, 19 96, reprinted with permission from The American Diabetes Association.) baseline fasting refeeding -3 6 -2 4 -1 2 0 12 24 36 48 60 72 84 96 108 120 132 study duration (hours) 100 80 60 40 20 leptin ... inadequacies Growth Hormone 329 0.0 10 20 30 40 50 60 70 80 90 100 prenatal -9 months til birth juvenile 1-1 2 years infantile birth -1 year adolescence...
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Basic medical endocrinology - part 8 pot
... Curiously, the IGF-II receptor is identical to the mannose- 6- phosphate receptor that binds mannose -6 - phosphate groups on newly synthesized lysosomal enzymes and transfers them from the trans-Golgi vesicles ... transfer mannose -6 - phosphate- containing glycoproteins from the extracellular fluid to the lysosomes by an endo- cytotic process. The IGF-II receptor plays an important role i...
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Basic medical endocrinology - part 9 pptx
... Horm. Res. 35, 301–332. Giudice, L. C. (1992). Insulin-like growth factors and ovarian follicular development. Endocr. Rev. 13, 64 1 66 9. Gougeon, A. (19 96) . Regulation of ovarian follicular development ... α-pregesterone 3βHSD 3βHSD 3βHSD 17βHSD 17βHSD P450c17 P450c17 = O androstenedione O P450scc P450c17 HO = O dehydroepiandrosterone testosterone O H O H O = O HO HO estrone estradiol-17...
Ngày tải lên: 10/08/2014, 18:21
Basic medical endocrinology - part 10 pdf
... effects, 332–334 growth mechanism, 332–333 osteoblast, 262 – 263 osteoclast, 262 – 264 osteocyte, 260 osteoid, 259– 260 parathyroid hormone effects, 269 –270 remodeling, 262 – 265 thyroid hormone effects, 289 vitamin ... 449–452 structure, 59 60 Proopiomelanocortin (POMC) processing, 61 62 regulation, 149–150 structure, 61 Prop-1, anterior pituitary development role, 62 Prostaglan...
Ngày tải lên: 10/08/2014, 18:21