Basic medical endocrinology - part 1 ppsx

... threatened detector hormone response hormone degrading apparatus 10 Chapter 1. Introduction O CH 2 O - P=O O O CH 3 O HN N O Thymine O CH 2 O - P=O O O O O CH 2 O - P=O O O O O CH 2 O - P=O O O O O CH 2 O - P=O O O O O O N N N N NH 2 Adenine O HN N N N H 2 N Guanine N NH 2 O N Cytosine O ... the 12 Chapter 1. Introduction transcription factors and cofactors pre-mRNA sp...

Ngày tải lên: 10/08/2014, 18:21

... 279                                    2345678 910 11 12 13 14 15 16 17 18 undetectable undetectable calcitonin (pg/ml) PTH (pg/ml) 4,000 3,000 2,000 1, 000 700 600 500 400 300 200  plasma calcium (m g /10 0 ml) PTH CT  Figure 13 Concentrations ... Berl,T., In “The Kidney,” 5th Ed., p. 8 81, Saunders, Philadelphia, 19 96, with permission.) N...

Ngày tải lên: 10/08/2014, 18:21

... Hormones 47 H-Ab H-Ab H-Ab H-Ab H-Ab H-Ab Ab Ab Ab Ab H H H H H H H H H + H H-Ab H-Ab H-Ab H-Ab H-Ab H-Ab Ab Ab Ab Ab H H H H H H H H H + H H H H H H H H-Ab H-Ab H-Ab H-Ab H-Ab H-Ab H-Ab Ab Ab Ab Ab H H H H H H + H Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab Ab A 10 0 10 1 0 20 40 60 80 10 0 550330 hormone ... into α-melanocyte-stimulating hormone (α-MSH) and the corticotropin-like intermed...

Ngày tải lên: 10/08/2014, 18:21

... inhibition. 11 8 Chapter 4. Adrenal Glands HO C=O CH 3 OH HO C=O CH 3 HO O P450c17P450c17 17 a-pregnenolone dehydroepiandrosteronepregnenolone O C=O CH 3 OH O C=O CH 3 O O P450c17P450c17 17 a-progesterone androstenedioneprogesterone O C=O CH 2 OH OH O OO O O HO ... HO HO HC C=O CH 2 OH 11 -deoxycortisol 11 -deoxycorticosterone C=O CH 2 OH OH C=O CH 2 OH cortisol corticosterone C=O CH 2 O...

Ngày tải lên: 10/08/2014, 18:21

... cell s glicentin IP2GLP -1 GLP-2 3 3-6 1 Figure 2 Cell-specific posttranslational processing of preproglucagon. GRPP, Glicentin-related pancreatic peptide; GLP -1 , glucagon-like peptide 1; GLP-2, glucagon-like peptide ... fructose -1 , 6-bisphosphate, is formed from fructose-6-phosphate by the action of an unusual bifunctional enzyme that catalyzes either phosphorylation of fructose-6-...

Ngày tải lên: 10/08/2014, 18:21

... expression of effects of 19 4 Chapter 5. The Pancreatic Islets -S-S- -S-S -S-S- COOH COOH insulin binding domain tyrosine kinase domain membane α-subunits β-subunits NH 2 NH 2 - Figure 18 Model of the ... or the hepatic action to increase Reinforcement 209 Insulin 19 1 glycogen glucose -1 - P I glucose-6-Pglucose II fructose-6-P fructose -1 , 6-P III hexose monophosphate shunt PEP py...

Ngày tải lên: 10/08/2014, 18:21

... (ng/ml a ) T3 (ng/ml) Postprandial 15 0 50 12 0 1. 9 1. 2 Postabsorptive 90 15 10 0 12 0 — 1. 15 Day 1 80 10 12 12 0 12 0 5.4 1. 15 Day 3 70 8 15 0 11 0 — 0.70 Day 5 70 7 15 0 11 0 6 .1 0.60 a Values for GH are from ... 45, 15 11 15 15, 19 96, reprinted with permission from The American Diabetes Association.) baseline fasting refeeding -3 6 -2 4 -1 2 0 12 24 36 4...

Ngày tải lên: 10/08/2014, 18:21

... Growth 3 2 1 0 -1 20 15 10 5 0 -5 -1 0 0 300 200 10 0 0 -1 00 nitrogen gm potassium mEq phosphorus mg sodium mEq control hGH 5 mg 10 days control hGH 10 mg 5 days control hGH 2.5 mg 10 days hGH long term Figure ... Chapter 11 . Hormonal Control of Reproduction in the Male body weight (grams) body length (cm) 13 0 12 0 11 0 10 0 90 80 010 20 days days 15 µg GH +0.0...

Ngày tải lên: 10/08/2014, 18:21

... α-pregesterone 3βHSD 3βHSD 3βHSD 17 βHSD 17 βHSD P450c17 P450c17 = O androstenedione O P450scc P450c17 HO = O dehydroepiandrosterone testosterone O H O H O = O HO HO estrone estradiol -1 7 β 1 2 3 5 7 8 9 10 11 12 13 14 15 16 17 18 19 HO 20 21 22 23 24 25 26 27 AB CD 4 6 cholesterol P450c17 CYP19 (aromatase) CYP19 (aromatase) OH Figure 6 Biosynthesis of ... receptor. 416 Cha...

Ngày tải lên: 10/08/2014, 18:21

... hormones anatomy cortex, 11 2 11 4 medulla, 15 6 blood supply, 11 4 functional overview, 11 2 histology, 11 3 11 4 medullary hormones, see Epinephrine; Norepinephrine Adrenergic receptors, types, 16 1 16 2 Adrenocorticotropic ... interactions, 13 9 14 1 cytokine interactions, 14 1 14 3 miscellaneous inflammatory mediator inhibition, 14 4 overview, 13 7 13 9 lung development role, 13...

Ngày tải lên: 10/08/2014, 18:21