Statistical Methods in Medical Research - part 7 ppsx
Statistical Methods in Medical Research - part 7 ppsx
... 0Á 372 0Á 377
(c) 150 67 0Á4 47 0Á382
(ac) 378 201 0Á532 0Á542
(bc) 32 16 0Á500 0Á458
(abc) 169 102 0Á604 0Á618
(d) 12 2 0Á1 67 0Á261
(ad) 13 7 0Á538 0Á404
(bd) 7 4 0Á 571 0Á325
(abd) 12 8 0Á6 67 0Á480
(cd) ... two-factor inter-
actions to be significant and it is prudent to try including each of the six two-factor
interactions in turn to the model. As an example, when the interact...
Statistical Methods in Medical Research - part 3 ppsx
... regression line is, from (7. 5),
17 168Á 47 À
À8869 75
2
10 262Á00
17 168Á 47 À 76 66Á39
9502Á08:
The residual mean square is, from (7. 6),
s
2
0
9502Á08=32 À2
316 74 :
7. 4 Sampling errors in regression ... 0Á05
SEb:
An important point about the t statistic (7. 18) is seen by writing b as b
yÁx
and
using (7. 3), (7. 5), (7. 6) and (7. 8). We find
t r
n À2
1 Àr
2
...
Statistical Methods in Medical Research - part 1 pptx
... 698
19.11 Intraclass correlation, 70 4
19.12 Disease screening, 70 7
19.13 Disease clustering, 71 1
20 Laboratory assays, 71 7
20.1 Biological assay, 71 7
20.2 Parallel-line assays, 71 9
20.3 Slope-ratio ... studies, 571
17. 4 Sampling errors in the
life-table, 574
17. 5 The Kaplan±Meier
estimator, 575
17. 6 The logrank test, 576
17. 7 Parametric methods, 582
17. 8 Regressio...
Statistical Methods in Medical Research - part 2 ppt
... of rats receiving diets with high and low protein content.
High protein Low protein
134 70
146 118
104 101
119 85
124 1 07
161 132
1 07 94
83
113
129
97
123
Total 1440 70 7
108 Analysing means and ... 12
x
1
120Á0
1
x
2
177 832
1
x
2
=n
1
172 800Á00
1
x À
x
1
2
5 032Á00
2
x 70 7
n
2
7
x
2
101Á0
2
x
2
73 959
2
x
2
=n
2
71 4 0...
Statistical Methods in Medical Research - part 4 pps
... À81,
À80, 78 , À46, À40, À34, 0, 29, 62, 75 , 106, 1 47, 1321
Y: Out-patients 32 À100
5
, À93, À89, À80, 78 , 75 , 74 , 72 , 71 ,
À66, À59, À41, À30, À29, À26, À20, À15, 20, 25,
37, 55, 68, 73 , 75 , ... 2Á05 1Á86 2Á01 8Á63
41 70 1Á58 1Á58 2Á21 7 07
Total 7 66 7 73 7 30 8Á18 30Á 87
250 Experimental design
Table 9.4 Clotting time (min) of plasma from three subjects, three methods...
Statistical Methods in Medical Research - part 5 pptx
... 69 8 12Á2 À4Á2
2Á40 70 14 29 7 À15 7
Group B: (continued)
2 70 73 39 34 74 Á3
1Á90 56 28 27 90Á1
2 78 83 12 29Á4 À 17 4
2Á 27 67 60 28Á831Á2
1 74 84 10 4Á15Á9
2Á62 68 60 36Á323 7
1Á80 64 22 19Á82Á2
1Á81 ... 5Á21 27 5Á29 43 4Á02
40 5Á29 29 5Á 17 25 3Á 67 41 4Á99
41 5Á52 33 4Á88 24 5Á82 48 3Á86
41 3 71 32 4Á50 32 4 77 47 4Á68
45 4Á02 31 4Á 47 23 5 71 53 4 74
49 5Á09 29 5Á12 25 4Á 4...
Statistical Methods in Medical Research - part 6 pps
... methods can be found in Goldstein (1995,
Chapter 4).
12.6 Longitudinal data
In many medical studies there is interest not only in observing a variable at a
given instant but in seeing how it changes ... Longitudinal data 4 47
can often help in circumstances where the analysis is intended to shed light on
deeper aspects of the problem being studied.
The linear methods, includin...
Statistical Methods in Medical Research - part 8 docx
... 0Á9 474 94 7
19 1 18 0Á0556 0Á9444 89Á5
32 1 17 0Á0588 0Á9412 84Á2
42 2 16 0Á1250 0Á 875 0 73 7
94 1 13 0Á 076 9 0Á9231 68Á0
2 07 1 10 0Á1000 0Á9000 61Á2
253 1 7 0Á1429 0Á8 571 52Á5
Applying ( 17. 14) ... data obtained. It
was originally developed in pioneering work by A. Wald (1902±50).
Implicit in any sequential analysis is the concept of a stopping rule, defining
the way in wh...
Statistical Methods in Medical Research - part 9 pptx
... 1Á683 0Á43 07 2Á33Á 87 172 6 75 6 1Á256 77 Á50 3Á85
2 90 3 2 27 43 5Á68 1 73 7 0Á 372 1 2 74 Á69 363 10Á661 1Á 876 81Á21 7 68
3 129 7 81 19 4Á32 1Á463 0Á2156 4Á66 73 236 10Á386 2Á403 121Á02 5Á 67
4 412 32 ... 53Á36 5Á 57
7 459 18 534 81 3Á 87 1Á353 0Á 072 0 13Á918Á81 1092 34Á0 47 8Á802 433 76 22Á 17
8 499 19 462 56 3Á18 1Á1 57 0Á 074 7 13Á415Á50 1036 26Á 973 8Á 473 480Á50 17 41
9...
Statistical Methods in Medical Research - part 10 docx
... 2Á 479 2 77 9 3 70 7
27 0Á1 27 0Á256 0Á389 0Á531 0Á684 0Á855 1Á0 57 1Á314 1 70 3 2Á052 2Á 473 2 77 1 3Á690
28 0Á1 27 0Á256 0Á389 0Á530 0Á683 0Á855 1Á056 1Á313 1 70 1 2Á048 2Á4 67 2 76 3 3Á 674
29 0Á1 27 0Á256 ... 6Á33 7 03 7 56 7 97 8Á328Á61 8Á 87 9Á10
7 0.05 3Á34 4Á16 4Á68 5Á06 5Á36 5Á61 5Á82 6Á00 6Á16
0.01 4Á95 5Á92 6Á54 7 01 7 377 Á68 7 94 8Á 17 8Á 37
8 0.05 3Á26 4Á04 4...