... W & Madura K (1998) Rad23 links DNArepair to the ubiquitin ⁄ proteasome pathway. Nature391, 715–718.23 Hiyama H, Yokoi M, Masutani C, Sugasawa K,Maekawa T, Tanaka K, Hoeijmakers JH & ... Yokosawa1and Hiroyuki Kawahara11 Department of Biochemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan2 Department of Molecular Oncology, The Tokyo ... Journal compilation ª 2005 FEBS 6373 the C-terminal half of Xrpn10c was necessary for Scythe binding (Fig. 4A, D). Remarkably, mutationalanalysis revealed that neither the UIM1 nor the UIM2domain...