cáo khoa học: " Developing a theory-based instrument to assess the impact of continuing professional development activities on clinical practice: a study protocol" doc
cáo khoa học: " Developing a theory-based instrument to assess the impact of continuing professional development activities on clinical practice: a study protocol" doc
... Université de Montréal, Montréal, QC , Canada; andCenter for Continuing Health Professional Education, McGill University,Montréal, QC, Canada. FL is Canada Research Chair in Implementation of Shared ... of Medical Regulatory authorities of Canada: Position statement2008 of the Federation of Medical Regulatory Authorities of Canada.4. Graham ID, Logan J, Harrison MB, Straus SE, Tetroe J, Caswell ... to assess the impact of CPD activities on clinical practice thwarts researchers’ comparisons of the effectiveness of CPD activities. Using an integrated model for the study of healthcare professionals’...
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báo cáo khoa học: " A randomized trial to assess the impact of opinion leader endorsed evidence summaries on the use of secondary prevention strategies in patients with coronary artery disease: the ESP-CAD trial protocol" doc
... University of Alberta, Canada, 3 The Department of Medicine, University of Calgary, Calgary, Canada, 4 The Royal Alexandra Hospital, Edmonton, Canada and 5 The University of Ottawa Health Research ... Ottawa, CanadaEmail: Finlay A McAlister* - finlay.mcalister@ualberta.ca; Miriam Fradette - miriam.fradette@ualberta.ca; Michelle Graham - MMGraham@cha.ab.ca; Sumit R Majumdar - me2.majumdar@ualberta.ca; ... patients attending the Univer-sity of Alberta cardiac catheterization laboratory in the 2003 year was 1.8 visits in six months. As we are assessing the impact of the Local Opinion Leader Statement...
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Báo cáo khoa học: Death inducer obliterator protein 1 in the context of DNA regulation Sequence analyses of distant homologues point to a novel functional role docx
... nuclear localization signaland a PHD domain (Zn finger) at the N-terminalregion. The long isoform also contains transcription fac-tor S domain II (TFS2M) (regulatory) and Spen para-log and ... a consequence of alterations in DNA regulation or chromatin stabil-ity. A similar case is the Suv39h histone methyltrans-ferase, in which both deletion and overexpression lead to alterations ... detail.Experimental proceduresComputational analyses The complete protein sequences of human DIDO isoforms 1and 2 were searched against PFAM [22,23] and SMART[24] databases to automatically detect domains;...
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Tài liệu Báo cáo khoa học: An engineered disulfide bridge mimics the effect of calcium to protect neutral protease against local unfolding docx
... bond to conformational andautoproteolytical stabilization. Particular attention ispaid to the role of calcium ions. For this reason, anenzyme variant with a mutation in the vicinity of cal-cium ... the unfolding.Calcium ions are the main contributory factor to enzyme stability The binding of calcium ions seems to be the mainsource of stabilization of the neutral protease fromB. stearothermophilus. Assuming ... wewere able to estimate the contribution of the incorpor-ation of calcium ions into pWT to the Gibbs freeenergy of activation of unfolding under native condi-tions. When 100 mm EDTA was added to...
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Báo cáo khoa học: Differing molecular mechanisms appear to underlie early toxicity of prefibrillar HypF-N aggregates to different cell types potx
... release largeamounts of proapoptotic factors, nor is the antiapop-totic Bcl-2 upregulated, and activation of the effectorcaspase 3 appears to result mainly from the early acti-vation of caspase ... in these cells, of caspase 8, followed by later activation of caspase 9. InIMR90 cells only moderate activation of caspase 3 wasfound as a consequence of the modest activation of caspase 9 and ... the cytosolic factor Apaf-1 activates the caspase-dependent apoptotic pathway, whereas AIF translo-cates to the nucleus inducing chromatin condensationand large-scale fragmentation of DNA [23,24].Similar...
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Báo cáo khoa học: Caspase-2 is resistant to inhibition by inhibitor of apoptosis proteins (IAPs) and can activate caspase-7 pot
... 5¢-CCACTTTAACTAATACT TTCA ACAT TTTC GG-3 ¢; 17–5¢-GGCCTCGAGAAGGGTTTTGCATC-3¢; 18, 5¢-GGATTCATGACTTTTAACAGTTTTGAAGG3¢; 19, 5¢-CCCCCGCGGCCGCTTAAGACATAAAAATTTTTTGCTTG-3¢; 20, 5¢-GGAATTCATGCACAAAACTGCCTCCC-3¢; ... 5¢-GGAATTCCATATGTGTGTAATTTTTCCGGTAG-3¢; 27, 5¢-CCCTCGAGTTTAATTGTGTTTAATATTAC-3¢; 28, 5¢-GCGGATCCATGACTTTTAACAGTTTTGAAGG-3¢; 29, 5¢-GAGAATTCTTAAGACATAAAAATTTTTTGCTTG-3¢; 30, 5¢-GCCTGCAGACTGCTGGCAACCGCAGCAGCCACTCGAGG-3¢; ... pGEX6P3-Caspase-7C18 6A . The primers used were: 1, 5¢-GGAAGATCTACTAGTATGGCCGCTGACAGGGGACGC-3¢;2,5¢-GCTCTAGACTATGTGGGAGGGTGCCTTGGG-3¢;3,5¢-GCAGATCTATGGACCAACAAGATGGAAAG-3¢;4,5¢-CGTCTAGACTCGAGTCCATCTTGTTGGTCTGTGGGAGGGTGTCCTGG-3¢;5,5¢-GGCTCGAGATGGCCGCTGACAGGGGACGC-3¢;6,5¢-GCTCTAGACTAATCTTGTTGGTCAACCC-3¢;7,5¢-GGGGATCCTGCGTGGTTCTTTCCATCTTGTTGGTCAACCCCACGATCAGTCTCATCTCCACGGGCGGCCTG-3¢;8,5¢-GCTCTAGATTAATCTTTATTGTCTAGGGAGTGTTCC-3¢;9,5¢-GGCGTCGACAGATACTGTGGAACACTCCCTAGACAATAAAGCTGGTCCTGTCTGC-3¢;...
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Báo cáo y học: "A new approach to understanding the impact of circadian disruption on human health'''' pps
... phase shifting and nocturnal mela-tonin suppression in humans appear to have similar, ifnot identical, functional relationships to optical radiation of the same spectral power distribution. The ... to understand the results of any ecological study of circadian disruption on human health or howlaboratory studies using animal models relate to the human condition. Second, with an understanding ... of the degree of circadian behavioral-entrainmentamong individuals. The data from the rats in Figure 9balso show a clear and statistically significant separation,but undoubtedly because of the...
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báo cáo khoa học: "R-CHOP versus R-CVP in the treatment of follicular lymphoma: a meta-analysis and critical appraisal of current literature" ppt
... 6:167-174.10. Falagas ME, Matthaiou DK, Bliziotis IA: The role of aminoglyco-sides in combination with a B-lactam for the treatment of bacterial endocarditis: a meta-analysis of comparative trials.J Antimicrob ... make the data accurate and comparable across all four studies,we reassigned patients into two broad stages: early stage(Ann-Arbor stages I and II) and late stage (Ann-Arborstages III and IV). ... AccessResearchR-CHOP versus R-CVP in the treatment of follicular lymphoma: a meta-analysis and critical appraisal of current literatureGanguly Siddhartha* and Patel VijayAddress: Division...
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báo cáo khoa học: " Innocent parties or devious drug users: the views of primary healthcare practitioners with respect to those who misuse prescription drugs" ppt
... Roche AM, Freeman T, McKinnon A: Health professionals’attitudes towards AOD-related work: Moving the traditional focus fromeducation and training to organizational culture. Drugs: Education,Prevention, ... time.Authors’ contributionsJS conceived of, and designed the study, was involved in the analysis andwriting of the paper. RB carried out the data collection, undertook the analysis and drafted the ... recommendation of their previous GP a ndan a dmission that, you know, they do have this pro-blem as a result of an accident years ago and yesthey are on oxycodone say. I’ve got a patient that’son...
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báo cáo khoa học: " Accelerating harm reduction interventions to confront the HIV epidemic in the Western Pacific and Asia: the role of WHO (WPRO)" pot
... support to OST/NSP study tours for the MoH in 2007 to sites in Hong Kong, Malaysia, Indo-nesia and Australia, including participation to providetranslation into a familiar language and organizationalcontext. ... was the main contributor for the Cambodianpiece of the paper. HT and NS contributed to the piece of the paper on Malaysia. HY and KP were the main respon-sible for the piece of the paper about ... Poipet.International rapid assessment response and evaluation (I-RARE). Cambo-dia 2005.30. National AIDS Authority (Cambodia): National strategic plan for a comprehensive and multisectoral response to HIV/AIDS2006–2010....
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