báo cáo khoa học: "Ultrasound microbubble-mediated delivery of the siRNAs targeting MDR1 reduces drug resistance of yolk sac carcinoma L2 cells" doc

... article as: He et al.: Ultrasound microbubble-mediated delivery of the siRNAs targeting MDR1 reduces drug resistance of yolk sac carcinoma L2 cells. Journal of Experiment al & Clinical Cancer ... attack of anti-cancer drugs [35-37]. In this study, we investigated whether the down- regulation of MDR1 could enhance the drug sensitivity of yolk...

Ngày tải lên: 10/08/2014, 10:21

... remain- ing lipids were further extracted by the addition of 2 mL of chloroform to the aqueous phase and by shaking (in the presence of the glass beads). The organic phases were then pooled and evaporated ... in the de novo synthesis of a given phospholipid, including PI. Hence, the rate of synthesis and the amount of CDP-DAG molecules that were used as substrate f...

Ngày tải lên: 29/03/2014, 22:21

... cancer and infiltration of the uncinate pancreatic process, on the anterior surface of which the tumor was located. En bloc resection of the tumor was performed wi th resection of the superior mesenteric ... ra-pan- creatic disease [1,2]. The most common unexpected finding at the time of pancreaticoduodenectomy in pancreatic carcinoma of the head and uncinate pro...

Ngày tải lên: 10/08/2014, 23:20

... fractions and the structure of the compound is determined. The activity of the chemo- preventive agent is then confirmed in experimental carcinogenesis models as shown in this study. Using the above ... focus on IxoA because of its abundance in the leaves and stems of the plant and its presence in the fruits. To examine the mechanism that might account for the effec...

Ngày tải lên: 23/03/2014, 10:20

... breed. At present, most of the dairy ewes in Israel (approximately 8000 head) are of the Assaf breed. The frequency of the Hb A allele in the F, of the cross was found ... similar in the two genotypes. In a small flock all the individuals carrying the rare allele can be the offspring of a common father. In this case devia...

Ngày tải lên: 09/08/2014, 22:22

... calculated from the equation of the num- ber of the false negative results divided by the sum of the number of the true positive results and the number of the false negative results. ThesoftwareprogramIBMSPSS ® 19 ... to that of the final determination of the status of the affected breast, as based upon those instances in which subsequent removal of add...

Ngày tải lên: 09/08/2014, 02:20

... placed at the point of insertion of the sternocleidomastoid muscle into the clavi- cular; the correct introduction of the needle was always confirmed by ultrasound guidance and by the easy aspira- tion ... pneumo- torax and to evaluate correct catheter position. At the end of treatment or when required, after the removal of the catheter, the tip was sent to the...

Ngày tải lên: 09/08/2014, 03:22

... Ad-bFGF-siRNA reduces the activation of upstream molecules and the expression of downstream molecules of STAT3 in U251 cells. (A) Ad-bFGF-siRNA (MOI = 100) reduces the phosphorylation/activation of ERK1/2 ... elevates the level of pSTAT3 Ser727 (Figure 3B) and future studies are required to examine the underlying mechanisms. To determine the potential mechanism of...

Ngày tải lên: 10/08/2014, 10:21

... number of doctors was only 7% of that required, and while the total number of professional nurses was 94% of requirement, there was considerable variation across facilities and districts. The adequacy ... rates. The research study was approved by the Free State Department of Health and the Committee for Research Ethics, Faculty of the Humanities, University of the...

Ngày tải lên: 10/08/2014, 10:23

... in one of 47 procedures (2.1%) [4]. How- ever, to the best of our knowledge, there have been no reports in the English literature describing treatment of HAP c omplicated by PTPE. In the present ... an occlusion of the segmental branch of his right hepatic artery was avoided. Our patien t was followed-up for four weeks after the procedure using US, and there was no evidenc...

Ngày tải lên: 10/08/2014, 23:20