báo cáo khoa học: "More expressions of BDNF and TrkB in multiple hepatocellular carcinoma and anti-BDNF or K252a induced apoptosis, supressed invasion of HepG2 and HCCLM3 cells" docx

... More expressions of BDNF and TrkB in multiple hepatocellular carcinoma and anti -BDNF or K252a induced apoptosis, supressed invasion of HepG2 and HCCLM3 cells. Journal of Experimental & Clinical ... significantly induced in anti -BDNF treated cells, which indicated that BDNF was required for supporting the survival of HepG2 and HCCL...

Ngày tải lên: 10/08/2014, 10:21

Ngày tải lên: 07/08/2014, 18:21

... AAAI Spring Symposium on Formal Theories of Commonsense knowledge, March 24-26, Stanford. Platt, J. (1998). Fast Training of Support Vector Ma- chines using Sequential Minimal Optimization. In B. Schölkopf, ... combined into a single finite state machine (one for each concep- tual area). By examining the number of states and transitions in the compiled finite state graphs, some in...

Ngày tải lên: 23/03/2014, 19:20

... treatment of cells with the transforming factor heregulin leads to increases in the levels of HSF1 and MTA1 (a component of the NuRD complex containing HDAC1 and HDAC2) proteins and to binding of HSF1 ... acquisition of the transactivat- ing capacity. In HSF, a C-terminal modulator domain is necessary for stress -induced hyperphosph- orylation of the protein and for t...

Ngày tải lên: 18/02/2014, 04:20

... cycling consisted of 40 cycles of denaturing at 94 °C for 30 s, annealing at 54 °C for 30 s and extension at 72 °C for 90 s. 5¢- and 3¢-rapid amplification of cDNA ends (RACE) In order to examine ... ligated into the corre- sponding site of the pFastBac1 vector (Invitrogen). The construction and propagation of recombinant AcMNPVs were performed according to the manufacturer’s...

Ngày tải lên: 18/02/2014, 04:20

... the binding of RNA-binding proteins to 3¢ UTR tran- scripts has been poorly described in plants. PUF proteins are a large family of RNA-binding proteins found in all eukaryotes. These proteins ... usually located in the 3¢ UTR. In recent years, and as a result of great efforts aiming to understand the mechanism of RNA control in animals, the function of a diverse number...

Ngày tải lên: 18/02/2014, 06:20

... could indicate that the corre- sponding hydroxyl groups are involved in protein binding. The results for the linebroadening measurements of protons H1a in the alpha and beta configurations, aHa1 and ... techni- ques for screening and identifying ligand binding to protein receptors. Angewandte Chemie-International Edi- tion 42, 864–890. 16 Mayer M & Meyer B (1999) Characterizati...

Ngày tải lên: 18/02/2014, 17:20

... system. Several chemokines bind to more than one receptor, and the majority of chemokine receptors have multiple ligands, leading to the generation of multiple pathways directing similar cellular ... joints. In addition to functioning in cell trafficking, several chemokines have other biological abilities. Chemokines stimulate FLS and chondrocytes to release in ammatory mediat...

Ngày tải lên: 18/02/2014, 18:20

... by evaluating thermal unfolding using differential scanning calorime- try (DSC). The results revealed a T m of 44.8 °C for VsEndA and 52.8 °C for VcEndA as shown in Fig. 6. The calorimetric enthalpy ... Smala ˚ s 1 and Elin Moe 1 1 Norwegian Structural Biology Centre, Faculty of Science, University of Tromsø, Norway 2 Department of Molecular Biotechnology, Faculty of Medicine,...

Ngày tải lên: 19/02/2014, 05:20

... fold and FMN binding site of the two respective proteins promp- ted a search for the presence of a residual redox activity in type II isomerase. In order to obtain maximum sensitivity in combination ... M15-pQEidi2. Preparation of the recombinant Idi-2 protein The recombinant E. coli strain M15-pQEidi2 was grown in Luria-Bertani broth containing ampicillin (180 mgÆL )1 )and...

Ngày tải lên: 19/02/2014, 13:20