báo cáo khoa học: " Platinum resistance in breast and ovarian cancer cell lines Niels Eckstein" pptx

... Access Platinum resistance in breast and ovarian cancer cell lines Niels Eckstein Abstract Breast and ovarian cancers are among the 10 leading cancer types in females with mortalities of 15% and ... cisplatin resistance research might be to investigate microRNAs. Thiol-containing proteins and Cisplatin resistance Among various mechanisms of platinum re...

Ngày tải lên: 10/08/2014, 10:21

... of the initial primary and nodal GTV, considering the preoperative diagnostics and the clinical and histological findings. The PTV1 includes the pGTV with a safety margin of between 1.0 and 1.5 ... postopera- tive radiotherapy and weekly cisplatin infusion for locally advanced squamous cell carcinoma of the head and neck: preliminary report of a randomized trial. Int J Radiat On...

Ngày tải lên: 09/08/2014, 10:21

... postoperative insulin resistance. Insulin resistance in type 2 diabetes Tyrosine phosphorylation of the insulin receptor increased over the same concentration range of insulin in cells from patients ... dissolved immediately in SDS and 2-mercaptoethanol with protease and protein phosphatase inhibitors, frozen within 10 s, and thawed in boiling water to minimize postincubatio...

Ngày tải lên: 07/03/2014, 16:20

... 1987; Munns and King, 1988; Richter, 1973; Schulte and Hinckley, 1987; Teskey et al., 1983; Tyree and Sperry, 1988). A summa- ry of the above work includes the following points: ... these proceedings. Running S.W. (1980) Field estimates of root and xylem resistances in Pinus contorta using root excision. J. Exp. Bot. 31, 555-569 Sachs J. (18...

Ngày tải lên: 09/08/2014, 02:21

... survival in invasive breast cancers [24]. In conclusion, we found that the incidence of sent inel lymph node metastasis in cases of pure DCIS was 0.39%. This incidence was lower than that in IDC-pre- dominant ... S, Vitelli CE, Rome Breast Cancer Study Group: Sentinel lymph node biopsy in women with pT1a or “microinvasive” breast cancer. Breast 2008, 17:395-400. 16. Zavag...

Ngày tải lên: 09/08/2014, 03:21

... 1 to 3 positive lymph nodes remains uncertain and is being examined in a rando- mized clinical trial”. Many surgeons and radiation oncol- ogist are not recommending PMRT to 1-3 axillary lymph ... therapy improve survival in breast cancer? A meta-analysis. J Clin Oncol 2000, 18:1220-1229. 24. Sotiriou C, Wirapati P, Loi S, et al: Gene expression profiling in breast cancer: unde...

Ngày tải lên: 09/08/2014, 09:20

... demonstrated in vitro growth inhibiting prop- erties in breast cancer cell lines without affecting normal breast cancer cells thus having a favorable toxicity profile. It was evaluated at 2008 ASCO in ... overexpressing human breast cancer cell lines in vitro.[9] It also inhibits the EGFR kinase and proliferation of EGFR-dependent cells.[9] It has been evaluated...

Ngày tải lên: 10/08/2014, 22:20

... results in the loss of pericytes and severe defects in the brain and heart, leading to vascular leakage and edema [55–57]. Ligand–receptor signaling between two types of cells may mediate cellu- lar ... dysfunction. Cell cell interaction in the neurovascular unit As discussed, all types of cells in the brain have unique roles and coordinate with each other to main- tain brai...

Ngày tải lên: 18/02/2014, 11:20

... molecules, solafe- nib and sunitinib, which inhibit a variety of tyrosine kinases including VEGFRs, have been approved for the treatment of renal cell cancer and liver cancer. These anti-angiogenic ... stress, resulting in an aggressive phenotype in terms of inva- sion and metastasis in vivo [35]. Late in its clinical course, malignant glioma is known to show extensive ce...

Ngày tải lên: 18/02/2014, 11:20

... made in dissecting stroke mechanisms involving excitotoxicity and ionic imbalance, oxidative and nitrosative stress, neuroinflammation and apoptotic-like pathways in neurons. However, clinically ... training increases endothelial progenitor cells, inhibits neointima formation, and enhances angiogene- sis. Circulation 109, 220–226. 77 Ziegelhoeffer T, Fernandez B, Kostin S, Heil M,...

Ngày tải lên: 18/02/2014, 11:20