báo cáo khoa học: "Effects of ulinastatin and docetaxel on breast cancer invasion and expression of uPA, uPAR and ERK" docx

... effects of ulinastatin and docetaxel on invasion of breast cancer cells and expression of uPA, uPAR and ERK, breast cancer MDA-MB-231 and MCF-7 cells. Methods: The nude mice were treated with PBS, ulinastatin, ... Open Access Effects of ulinastatin and docetaxel on breast cancer invasion and expression of uPA, uPAR and ERK Jie L...

Ngày tải lên: 10/08/2014, 10:21

... hypofractionation and those treated by conventional fractionation [9]. How- ever, the UK randomised trial [ 4] on hypofractionated radiotherapy using fraction sizes of 2, 3 and 3.3 Gy in 1410 randomized ... Ezzat S: Hypofractionation versus conventional fractionation radiotherapy after conservative treatment of breast cancer: Early Skin Reactions and Cosmetic Results. J. of t...

Ngày tải lên: 09/08/2014, 09:20

... myoblast proliferation and differentiation ⁄ hypertrophy. In particular, activation of the Ras–Raf–Mek–Erk pathway stimulates proliferation, contribu- ting to Neu2 downregulation. On the contrary, activation of ... transla- tion by addition of antisense oligonucleotides strongly decreases myotube formation in L6 rat myoblasts [21]. The ability of sialidases to work on glycoconju...

Ngày tải lên: 19/02/2014, 06:20

... HBx alone does not directly contribute to BetA- induced SOD2 suppression and HBV inhibition, whereas HBx translocation to mitochondria could be a consequence of BetA-induced SOD2 suppression and subsequent ... mitochondria, and this can subsequently trigger mitochondrial dysfunction and apoptosis. Altered SOD2 expression is considered to be both beneficial and detrimental. For in...

Ngày tải lên: 16/03/2014, 01:20

... Breast cancer Breast cancer is the most common malignancy among women in the Western world and constitutes 18% of all cancers in women. In Denmark approximately 3800 women develop breast cancer ... Translational Breast Cancer Research (DCTB), to fight breast cancer. DCTB hosts scientists working in various areas of preclinical cancer research (cell cycle control, in...

Ngày tải lên: 30/03/2014, 15:20

... lungs, liver, bones and brain. Solitary adrenal metastasis is extremely rare. Due to the rarity of this condition, the optimal treatment is unclear. We report the first case of IDC of the breast metastasizing ... common type of the breast cancer, which has been reported to constitute approximately 70-85% of all invasive breast carcinomas[1]. Usually, IDC can metastasize to...

Ngày tải lên: 09/08/2014, 03:21

... Identification of a novel truncating PALB2 mutation and analysis of its contri- bution to early-onset breast cancer in French-Canadian women. Breast Cancer Res 2007, 9:R83. 8. Rahman N, Seal S, Thompson ... confined population of Iceland, linkage analysis was done on 111 individuals, thereof 61 breast cancer cases, from 9 high-risk non-BRCA1/BRCA2 breast cancer famil...

Ngày tải lên: 11/08/2014, 07:20

... Lancet Oncol 2003, 4(9):565-573. 13. Chen J, Sun Z, Tao Y: Expression and significance of Ulinastatin and cyclophosphamide in breast cancer cell proliferation and invasion and MMP 9 expression. ... expression in breast cancer and the effects of ulinastatin on its expression level. Chin J Biol 2009, 22:548-551. 10. Gong Y, Sun X, Huo L: Expression of ce...

Ngày tải lên: 10/08/2014, 10:21

... TQ concentrations of 5 and 20 lm, whereas it decreases at a concentration of 100 lm (corresponding to the recovery of proteasome activity). At the same time, increases in TQ concentra- tion resulted ... presence of Z- LLF-CHO (mean values ± standard deviations of five independent determinations). A B Fig. 4. Detection of quinone adducts. 20S isolated immunoprotea- somes were trea...

Ngày tải lên: 15/03/2014, 11:20

... change in the conformation of this loop. Changes in the conformation of the backbone at this point and changes in the orientation of other side chains, as a result of the introduction of the large ... protein was dimeric under our standard conditions of 1 mgÆmL )1 and 15 °C. Physio- logical conditions of ionic strength and temperature promoted the dissociation of both va...

Ngày tải lên: 16/03/2014, 06:20