báo cáo khoa học: " Multi-drug resistance 1 genetic polymorphism and prediction of chemotherapy response in Hodgkin’s " pot
báo cáo khoa học: " Multi-drug resistance 1 genetic polymorphism and prediction of chemotherapy response in Hodgkin’s " pot
... 30:68 http://www.jeccr.com/content/30 /1/ 68 Page 3 of 8 RESEARCH Open Access Multi-drug resistance 1 genetic polymorphism and prediction of chemotherapy response in Hodgkin’s Lymphoma Nizar M Mhaidat 1* , Osama Y Alshogran 1 , ... at diagnosis Median 31 27.5 15 -20 16 (16 .7) 17 (50) 21- 30 32 (33.3) 5 (14 .7) 31- 40 18 (18 .8) 5 (14 .7) > 40 30 ( 31....
Ngày tải lên: 10/08/2014, 10:21
Báo cáo khoa học: Membrane type-1 matrix metalloprotease-independent activation of pro-matrix metalloprotease-2 by proprotein convertases docx
... hemopexin-like domain (C domain) of human gelatinase A (matrix metalloproteinase-2) requires Ca 2+ for fibronectin and heparin binding. Binding properties of recombinant gelatinase A C domain to extracellular ... processing of MMP-2 in HEK293F, MCF-7 and MDAH 2774 cells. Cells were treated with aprotinin (20 lgÆmL 1 ), chymostatin (10 lgÆmL 1 ), leupeptin (20 lgÆmL 1 ) and...
Ngày tải lên: 16/03/2014, 00:20
Tài liệu Báo cáo khoa học: Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores pdf
... 15 2 10 2 7 1 19 4 26 3 20% TFE 62 5 26 2 0 1 0 1 3 1 9 6 60% TFE 61 5 27 2 0 1 0 2 1 1 11 5 0.5 m M SDS 63 6 19 3 1 2 0 1 4 4 13 4 4m M SDS 61 4 25 3 0 1 0 1 4 2 10 6 Bax-a6 Buffer 13 1 10 1 ... Polydispersity Peak intensity (kc ⁄ s) None 0 13 0.3 ± 1. 5 0 .11 ± 0.05 14 1.2 ± 3.6 Bax-a5 500 12 9.6 ± 1. 2 0 .12 ± 0.03 14 7.0 ± 3.5 250 13 1.4 ± 1. 2 0 ....
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khoa học: Arginine ethylester prevents thermal inactivation and aggregation of lysozyme pptx
... in Table 1. The rates o f inactivation and aggregation d epend on the protein Fig. 1. Thermal inactivation and aggregation of lysozyme in the presence of additives. T he samples containin g 1. 0 ... Differences in the c hemi cal properties of Arg and ArgEE. (A) Determ ina tio n of p K a values of amino groups on Arg and ArgEE. A small q uantity of 1. 0 M NaOH wa s...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: The undecided serpin The ins and outs of plasminogen activator inhibitor type 2 pdf
... 76, 812 – 819 . 45 Chuang TL & Schleef RR (19 99) Identification of a nuclear targeting domain in the insertion between helices C and D in protease inhibitor -10 . J Biol Chem 274, 11 194 11 198. 46 ... binding sites for several ARE binding proteins, including the stabilizing protein HuR [86] and the mRNA destabilizing protein tristetr- aprolin (TTP) [87]. HuR is a member of...
Ngày tải lên: 20/02/2014, 02:21
Tài liệu Báo cáo khoa học: A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action docx
... with 10 % fetal bovine serum (Gibco-Life Technology) and Penicillin-Streptomycin-Glu- tamine 1X (Gibco-Life Technology). Cell lines were main- tained at 37 °C in a humidified incubator containing 10 % CO 2 mixedwithair. Cytotoxicity ... superreactivity of cysteine residues 31 and 32 of seminal ribonuclease. Biochemistry 24, 10 98 11 04. 19 . D’Alessio, G., Malorni, M.C. & Pa...
Ngày tải lên: 20/02/2014, 11:20
Báo cáo khoa học: Organizational constraints on Ste12 cis-elements for a pheromone response in Saccharomyces cerevisiae docx
... containing a single PRE (IS1430 ⁄ 14 31) and full-length Ste12 (lane 1) , Ste12 1 476 (lane 2), Ste12 1 350 (lane 3) and Ste12 1 215 (lane 4). Full-length Ste12 was mixed with 1 476 (lane 5), 1 350 ... positioned to a binding site for Tec1 [15 , 21] . However, an examination of the arrangement of Ste12 and Tec1 binding sites in promoters of this class reveals a variety...
Ngày tải lên: 06/03/2014, 22:21
Báo cáo khoa học: Evolutionary changes to transthyretin: structure and function of a transthyretin-like ancestral protein doc
... the N-terminal and C-terminal regions [11 ]. In order to distinguish between the two protein families in greater detail, a comparative analysis of TLP and transthy- retin sequences was performed [11 ]. In ... identified in all kingdoms [19 ]. The aerobic degradation of purines is dependent on the oxidation of hypoxanthine and xanthine to uric acid via xanthine dehydrogenase...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Post-ischemic brain damage: pathophysiology and role of inflammatory mediators ppt
... Feurerstein GZ (19 93) Interleukin -1- beta messenger RNA expression in ischemic rat cortex. Stroke 24, 17 46 17 51. 11 4 Buttini M, Sauter A & Boddeke H (19 94) Induction of interleukin-1beta mRNA ... increase very early following permanent MCAO [11 5 ,11 6] and peak within hours of reperfusion in transient focal ischemic models in rodents [97 ,11 7 ,11 8]. The main source...
Ngày tải lên: 07/03/2014, 03:20
Báo cáo khoa học: Interactions between coenzyme B12 analogs and adenosylcobalamin-dependent glutamate mutase from Clostridium tetanomorphum pot
... 5967 O NH 2 CONH 2 CONH 2 H 2 NOC H 2 NOC CONH 2 O OH NH H N N N N NH 2 O OH HO HH Co N N N N AdoCbi O NH 2 CONH 2 CONH 2 H 2 NOC H 2 NOC CONH 2 O O - P O HN H O O N N N N NH 2 O OH HO HH Co N N N N N N N N NH 2 O OH O O - P O O AdoCbi-GDP O NH 2 CONH 2 CONH 2 H 2 NOC H 2 NOC CONH 2 O NH H 3 C H N N N N NH 2 O OH HO HH Co N N N N AdoCbi-P P O O O - O ATP ADP GTP PP i Cobinamide kinase Cobinam...
Ngày tải lên: 07/03/2014, 04:20