báo cáo khoa học: " Small interference RNA targeting tissue factor inhibits human lung adenocarcinoma growth in vitro and in vivo" ppsx

báo cáo khoa học: " Small interference RNA targeting tissue factor inhibits human lung adenocarcinoma growth in vitro and in vivo" ppsx

báo cáo khoa học: " Small interference RNA targeting tissue factor inhibits human lung adenocarcinoma growth in vitro and in vivo" ppsx

... this article as: Xu et al.: Small interference RNA targeting tissue factor inhibits human lung adenocarcinoma growth in vitro and in vivo. Journal of Experimental & Clinical Cancer Research 2011 ... RESEARC H Open Access Small interference RNA targeting tissue factor inhibits human lung adenocarcinoma growth in vitro and in vivo...
Ngày tải lên : 10/08/2014, 10:21
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Báo cáo khoa học: "Small interference RNA profiling reveals the essential role of human membrane trafficking genes in mediating the infectious entry of dengue virus" pdf

Báo cáo khoa học: "Small interference RNA profiling reveals the essential role of human membrane trafficking genes in mediating the infectious entry of dengue virus" pdf

... by the joint action of machinery that includes clathrin heavy and light chains, adaptor complexes (AP1 and AP2), membrane-bending proteins such as epsin, amphi- physin, syndapin and endophilin A, ... clathrin heavy chain and dynamin inhi- bits uptake by 70% or more (Figure 2 and Additional File 2). In addition, knockdown of several other endocy- tic proteins includ ing epsin, synd...
Ngày tải lên : 12/08/2014, 04:21
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báo cáo khoa học: "Adenovirus-mediated siRNA targeting Bcl-xL inhibits proliferation, reduces invasion and enhances radiosensitivity of human colorectal cancer cells" ppt

báo cáo khoa học: "Adenovirus-mediated siRNA targeting Bcl-xL inhibits proliferation, reduces invasion and enhances radiosensitivity of human colorectal cancer cells" ppt

... producing siRNA using the polymerase III promoter offer more efficient siRNA delivery and are showing promise both in vitro and in vivo [25]. In our research, adenovirus-mediated siRNA targeting ... mRNA and protein in CRC cells and normal human intestinal epithelial cell line. Then, adenovirus-mediated RNA interference technique was employed to inhibit the express...
Ngày tải lên : 09/08/2014, 02:21
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Báo cáo khoa học: Interaction of the general transcription factor TnrA with the PII-like protein GlnK and glutamine synthetase in Bacillus subtilis potx

Báo cáo khoa học: Interaction of the general transcription factor TnrA with the PII-like protein GlnK and glutamine synthetase in Bacillus subtilis potx

... was observed during this kind of shift experiment in B. sub- tilis AmtB-deficient and GlnK-deficient strains, despite TnrA being soluble in these cells [12,15]. To gain dee- per insights in the involvement ... collected, and after rigorous washing in nonionic detergent-containing buffer and elution of antibody- bound protein, the samples were separated by SDS ⁄ PAGE and analyzed...
Ngày tải lên : 06/03/2014, 00:21
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Báo cáo khoa học: The heterogeneity of mast cell tryptase from human lung and skin Differences in size, charge and substrate affinity ppt

Báo cáo khoa học: The heterogeneity of mast cell tryptase from human lung and skin Differences in size, charge and substrate affinity ppt

... lgÆmL )1 ,andtheblots washed and incubated with diaminobenzidine and hydrogen peroxide. A combination of the biotinylated lectins Sambu- cus nigra agglutinin (SNA; 10 lgÆmL )1 )andMaackia amurensis agglutinin (MAA; ... differing values of K m and k cat . Fig. 9. pH profile of human skin and lung tryptase in the presence and absence of heparin. (j) skin tryptase, no heparin (h)...
Ngày tải lên : 31/03/2014, 07:20
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báo cáo khoa học: " Effects of RNA interference-mediated gene silencing of JMJD2A on human breast cancer cell line MDA-MB-231 in vitro" pptx

báo cáo khoa học: " Effects of RNA interference-mediated gene silencing of JMJD2A on human breast cancer cell line MDA-MB-231 in vitro" pptx

... expressed in human tissues and cell lines, and high endogenous expression of JMJD2A mRNA was found in several cell types, including human T-cell lymphotropic virus 1- infected cell lines, the ... well and incubated in RPMI 1640 medium (GIBCO, Invitrogen, USA) conta ining 10% FBS (GIBCO, Invitrogen, USA). RPMI 1640 med- ium containing 10% FBS was replaced by serum-free Opti-MEM...
Ngày tải lên : 10/08/2014, 10:21
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Tài liệu Báo cáo khoa học: Transient DNA ⁄ RNA-protein interactions docx

Tài liệu Báo cáo khoa học: Transient DNA ⁄ RNA-protein interactions docx

... investing time and effort in preparing and analyzing the full-length protein can be extremely rewarding, as shown by the information obtained with the tumor suppressor protein BRCA2 and its interac- tion ... structure facilitating protein bind- ing (indirect) and specific amino acid–base contacts (direct). A recent examination of proteinÆnucleic acid structures has shown how minor gr...
Ngày tải lên : 14/02/2014, 19:20
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Tài liệu Báo cáo khoa học: Small molecule regulation of Sir2 protein deacetylases ppt

Tài liệu Báo cáo khoa học: Small molecule regulation of Sir2 protein deacetylases ppt

... for silencing at telomeres, rDNA and the silent mating type loci, and for maintaining genome integrity [5,6]. In addition to silencing, Sir2 activity is linked to lifespan extension in yeast [7], worms ... 26 was not as potent as splitomicin in inhibiting ySir2. In addition to studies in yeast, sirtinol and splitomicin have been used as general sirtuin inhibitors in mamma- l...
Ngày tải lên : 20/02/2014, 01:20
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Tài liệu Báo cáo khoa học: Efficient RNA ligation by reverse-joined hairpin ribozymes and engineering of twin ribozymes consisting of conventional and reverse-joined hairpin ribozyme units ppt

Tài liệu Báo cáo khoa học: Efficient RNA ligation by reverse-joined hairpin ribozymes and engineering of twin ribozymes consisting of conventional and reverse-joined hairpin ribozyme units ppt

... fluorescent and affinity labeling of RNA using a small engineered ribozyme. Chembiochem in press. 19 Feldstein A, Buzayan JM & Bruening G (1989) Two sequences participating in the autolytic processing ... hairpin ribozyme by dissecting the two domains at the hinge between helix 2 and helix 3 and rejoining helix 4 to helix 1 via a linker of six unpaired residues [27] (Fig. 1)....
Ngày tải lên : 20/02/2014, 01:20
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