báo cáo khoa học: " Regulation of hypoxia inducible factor-1

Báo cáo khoa học: Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains pot

... 239 FIH ). Instead the imidazole ring is sand- wiched between the side chains of His 199 FIH that forms part of the catalytic triad and the aromatic ring of Tyr 102 FIH . The side chain of Gln 239 FIH moves ... Proteomics-based identiﬁcation of novel factor inhibiting hypoxia- inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyri...

Ngày tải lên : 28/03/2014, 23:20

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báo cáo khoa học: " Regulation of hypoxia inducible factor-1a expression by the alteration of redox status in HepG2 cells" pdf

... Regulation of hypoxia inducible factor-1a expression by the alteration of redox status in HepG2 cells. Journal of Experimental & Clinical Cancer Research 2011 30:61. Jin et al. Journal of Experimental ... expression of HIF-1a protein. Combining the previous researches with our results, we considered the mechanism, the redox status influencin...

Ngày tải lên : 10/08/2014, 10:21

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Tài liệu Báo cáo khoa học: Erythrochelin – a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea docx

... carried out by the C-terminal C 5 -domain, catalyzing the intramolecular nucleophilic attack of the L-hOrn 3 a-amino group onto l-haOrn 4 . Taking into account that the synthetases involved in the bio- synthesis ... encoded in the etc gene cluster. The N-terminal C-domain of the NRPS catalyzes the a-N-acetylation of haOrn 1 in cis. Cyclorelease of the assem...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Control analysis as a tool to understand the formation of the las operon in Lactococcus lactis doc

... all the genes involved in the pathway in the same operon; the cell can then respond quickly to changes in the environ- ment by changing the expression of only a few genes and using the protein-synthesizing ... by the second gene in the las operon (Fig. 1). In order to obtain strains with increased PK activity an additional copy of the pyk gene was recom...

Ngày tải lên : 19/02/2014, 17:20

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Tài liệu Báo cáo khoa học: Long-distance interactions between enhancers and promoters The case of the Abd-B domain of the Drosophila bithorax complex pdf

... later than in the case of the histone gene cluster [10]. This difference in the tim- ing of somatic pairing perhaps reﬂects the difference between the complexities of the regulation of the two systems: ... the effects of the neighboring chromatin (e.g. heterochro- matinization) if the reporter is ﬂanked by two of them. The apparent function of the...

Ngày tải lên : 20/02/2014, 01:20

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Báo cáo khoa học: Cyclic ADP-ribose requires CD38 to regulate the release of ATP in visceral smooth muscle ppt

... acetylcholine-induced produc- tion of cADPR [28]. Instead, the enhancing effect of cADPR on the spontaneous release of ATP is inhibited by 8-Br-cADPR, a speciﬁc antagonist of cADPR receptors in intracellular ... preparation. Of particular importance is the ﬁnding that exogenous cADPR failed to increase the spontaneous release of ATP in the absence of CD38. In o...

Ngày tải lên : 05/03/2014, 23:20

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Báo cáo khoa học: Nck-1 selectively modulates eIF2aSer51 phosphorylation by a subset of eIF2a-kinases docx

... Nevertheless, these data further support the notion of the speciﬁcity in Nck regulation of eIF2a- Ser51 phosphorylation by eIF2a-kinases. Having recently shown that Nck is involved in the maintenance of ... of reversing factor in the initiation of protein synthesis. Proc Natl Acad Sci USA 80, 2559–2563. 5 Matts RL & London IM (1984) The regulation of init...

Ngày tải lên : 07/03/2014, 05:20

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Báo cáo khoa học: Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase doc

... portion of the fusion protein was degraded by the host proteases. On the other hand, attempts to produce a His-tagged version of the Rv1771 protein by using the pRSETc or the Gateway pDEST17 expression ... Escherichia coli. The recombinant protein contained an engineered enterokinase cleavage site in the junction between the GST tag and the Rv1771 sequence. Upo...

Ngày tải lên : 07/03/2014, 12:20

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Báo cáo khoa học: Novel c-carboxyglutamic acid-containing peptides from the venom of Conus textile docx

... and postpeptides of Gla-containing conotoxins [20]. In addi- tion, the newly identiﬁed propeptides contain a putative consensus sequence found in the precursors of Gla-containing conotoxins but not in the ... Gla(3)–TxVI: conﬁrmation of the presence of BrTrp. Product ion mass spectrum of the doubly charged ion at m ⁄ z ¼ 660.18. The isotopic distribution of th...

Ngày tải lên : 23/03/2014, 11:20

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Báo cáo khoa học: Examining multiprotein signaling complexes from all angles The use of complementary techniques to characterize complex formation at the adapter protein, linker for activation of T cells pdf

... for the lack of in vivo binding of Gads to phosphorylated LAT tyrosine 132) and the formation of multiprotein signaling complexes (the reason for the lack of detectable in vivo association of ... biophysical methods. These approaches offer the opportunity to probe the basic mechanism of protein–protein interactions in great detail. First, the afﬁnity of the...

Ngày tải lên : 23/03/2014, 15:21

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