báo cáo khoa học: " Maintenance therapy in NSCLC: why? To whom? Which agent?" ppt

... 2) continuing only the third-genera- tion non-platinum compound used in the induction regimen; 3) switching to a different agent after induction therapy. Continuing first-line induction therapy The ... strategy should be to co ntinue the same therapy withholding platinum, in an attempt at consolidating disease control and increasing survival, maintaining tolerability within acce...

Ngày tải lên: 10/08/2014, 10:21

... (1969) Inhibitors around the antimycin-sensitive site in the respiratory chain. In Inhibitors ) Tools in Cell Research (Bucher Th & Sies H, eds), pp. 282–300. Springer, Berlin. 39 Gonzalez ... of acetoin did not help to restore the redox balance (Table 2). This could indicate that, in these yeasts, the mechanisms for shuttling NADH reducing equiva- lents from mitochondria to c...

Ngày tải lên: 19/02/2014, 02:20

... regulated by GTP binding and hydrolysis [4–7]. Toc34 GDP interacts with the second G-protein in the Toc complex, Toc159, and simultaneously transfers the preprotein to Toc159. Toc159 action facilitates ... QORH into the inner enve- lope of chloroplasts was shown to depend on targeting information present in the C-terminus of the pre- protein [11]. Therefore, we constructed a pTic22DC...

Ngày tải lên: 23/03/2014, 07:20

... possible to obtain local con- trol in the range of 89-100% using radiotherapy in low or moderate doses as 25-36 Gy. A summary of findings of some of published major studies on the issue is shown in table ... (2.1%), and minor retinopathy in one (2.1%). Cataract, minor retinopathy and corneal ulceration occurred in 20.7% patients among those treated with a dose ≤ 36 Gy (6 on 29 pat...

Ngày tải lên: 09/08/2014, 10:20

... proteins involved in the regulation of cell growth [15]. The proteasome activates nuclear factor-B (NF-B) signaling by degrading IB kinase (eg, the NF- B inhibitory protein), resulting in the ... the mTOR inhibitors [40,44,45], and one group of investiga- tors recommends treating this adverse event with statins in patients continuing on long-term temsirolimus treat- ment [41]. Pulmo...

Ngày tải lên: 10/08/2014, 22:21

... ledge into account, which is sometimes necessary for determining contrast. For instance, the contrast in (1) is based on the knowledge that kicking the ball into the wrong goal implies scoring ... givenness, to indicate that it constitutes contrastive information. 2 Predicting contrastive accent In this section I discuss two approaches to predicting contrastive accent, whic...

Ngày tải lên: 22/02/2014, 03:20

... difficult to distinguish between the effect of declining temperature and increasing soil water content as both occur together in autumn and winter, and both reverse together in ... an increasing sink for carbon as atmospheric CO 2 is increased and photosynthesis stimulated [16]. Conversely, anticipated temperature increases resulting from increasin...

Ngày tải lên: 08/08/2014, 14:21

... approach to the problem of vas- cularization in tissue engineering and has the advantage of pointing to a solution for the problem of nutrition and oxygenation in the in vitro phase of engineering ... construct, which was designed as a preliminary in vitro model. The major concern was to demonstrate the engineering of capillary- like networks in vitro, which show patent br...

Ngày tải lên: 11/08/2014, 23:22

... Heat shock 27kDa protein 1 NM_006417 IFI44 Interferon-induced protein 44 M13436 INHBA Inhibin, beta A (activin A) NM_005538 INHBC Inhibin, beta C AF073310 IRS2 Insulin receptor substrate 2 NM_005101 ... PPP1R3C encodes an inhibitory subunit of pro- tein phosphatase and is known to bind liver glycogen in response to high levels of insulin. It belonging to a family of pro-inflammatory...

Ngày tải lên: 12/08/2014, 04:21

... Mutations in domains remote from the chemical chaperone binding active-site domain may continue to be subject to mis- folding, despite binding-induced stabilization of the active-site domain, especially ... chap- eroning of GC increases the folding and traf- ficking efficiency of GC, increasing its concentration in the lysosome, restoring par- tial function, and offering the possibility...

Ngày tải lên: 18/02/2014, 16:20