báo cáo khoa học: "Bostrycin inhibits proliferation of human lung carcinoma A549 cells via downregulation of the PI3K/Akt pathway" pdf
báo cáo khoa học: "Bostrycin inhibits proliferation of human lung carcinoma A549 cells via downregulation of the PI3K/Akt pathway" pdf
... apoptosis of human lung cancer cells without downregulation of Akt. Cancer Biol Ther 2004, 3:1092-1098, discussion 1099-1101. 7. Altomare DA, Testa JR: Perturbations of the AKT signaling pathway in human ... involved in the effects of bostrycin on A549 cells. We showed by western blots that there was a decrease in the expression of p110a protein over time in bostr...
Ngày tải lên: 10/08/2014, 10:21
Báo cáo khoa học: Full-length adiponectin protects hepatocytes from palmitate-induced apoptosis via inhibition of c-Jun NH2 terminal kinase doc
... the UPR. However, in the absence of adiponectin, thasi- gargin and palmitate elevated the expression of several genes involved in the UPR in HepG2 cells (Fig. 3). In the presence of thapsigargin or ... if so, whether this involved: (a) augmentation of the unfolded protein response (UPR); (b) up-regulation of members of the inhibitor of apoptosis protein (IAP) fam...
Ngày tải lên: 29/03/2014, 23:20
Báo cáo khoa học: "A rare tumoral combination, synchronous lung adenocarcinoma and mantle cell lymphoma of the pleura" docx
... con- cerned the synchronous presence of adenocarcinoma located in the cecum and MCL involving the colon, the terminal ileum and the regional lymph nodes [13]. Another case of synchronous existence of ... approval of the version to be published. GTK has assisted the surgeon, did the collection of the data and have been involved in the design and drafting of the...
Ngày tải lên: 09/08/2014, 07:22
Báo cáo khoa học: TRAF6 and C-SRC induce synergistic AP-1 activation via PI3-kinase–AKT–JNK pathway pptx
... not detect interaction of TRAF6 with c-Src KD, in spite of the similar expression amounts of these two molecules. These data suggested that the kinase activity of c-Src is essential for the interaction ... then examined whether the kinase activity of c-Src is required for the interactionwithTRAF6.FLAG-taggedTRAF6wascoex- pressed with wild-type or kinase-dead mutant of c-...
Ngày tải lên: 31/03/2014, 07:20
báo cáo khoa học: " Creating a knowledge translation trainee collaborative: from conceptualization to lessons learned in the first year" pdf
... to the meet- ing. The aim of the review process was to assemble a group of trainees that could both contribute to and gain from capacity building in the field of KT. Thirty trainees attended the ... contributions EC developed the outline of the paper, coordinated the content from all authors, and prepared the first draft with assistance from RU and HW. All authors co...
Ngày tải lên: 10/08/2014, 11:20
Báo cáo khoa học: Dehydroepiandrosterone inhibits the proliferation and induces the death of HPV-positive and HPV-negative cervical cancer cells through an androgen- and estrogen-receptor independent mechanism pptx
... and it is the second most common cause of death from can- cer among Mexican women [21]. Therefore, the aim of this work was to evaluate the effect of pharmacological doses of DHEA on the proliferation ... the malignant state of the cells. HeLa cells are an advanced-stage cervical cell carcinoma [27], in comparison with the other cell lines used for which no stag...
Ngày tải lên: 16/03/2014, 00:20
Báo cáo khoa học: Hexadecylphosphocholine inhibits phosphatidylcholine biosynthesis and the proliferation of HepG2 cells pot
... biosynthesis of PC in HepG2 cells at the level of CT activity. It interferes with the translocation process of CT from the cytosol to the membrane and finally leads to an inhibition of the biosynthesis ... interference of HePC on this regulatory process. Thence, HePC could act on CT activity either by promoting the release of the enzyme from the membrane to the...
Ngày tải lên: 17/03/2014, 11:20
Tài liệu Báo cáo khoa học: Oxidation inhibits amyloid fibril formation of transthyretin ppt
... day of incubation, 60% of the unoxi- dized V30M TTR was in the supernatant, whereas 80% of the oxidized protein was in the supernatant. After 3 days of incubation, the values were 27% for the ... nm) of the oxidized proteins divided by the turbidity of the unoxidized proteins. Oxidation reduced fibril growth of the WT protein by 76% after 1 day to 60% afte...
Ngày tải lên: 19/02/2014, 05:20
Báo cáo khoa học: Rotenone inhibits mammalian cell proliferation by inhibiting microtubule assembly through tubulin binding Pallavi Srivastava and Dulal Panda ppt
... reassembly of microtubules in HeLa cells Microtubules were depolymerized by incubating the HeLa cells on ice for 1 h. Then, the kinetics of the reassembly of the microtubules in live HeLa cells was B A Fig. ... respect to the antiproliferative mechanism of action of rotenone. Results Effects of rotenone on the proliferation HeLa and MCF-7 cells Rotenone inhib...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Bacitracin inhibits the reductive activity of protein disulfide isomerase by disulfide bond formation with free cysteines in the substrate-binding domain pptx
... ion mode CID-TOF ⁄ TOF MS analysis of the same precursor yielded the corresponding signature peaks (m ⁄ z 1404.88, 1438.82 and 1470.80) of the other part of the disulfide bond, i.e. the negatively ... making them the active antimicrobial compounds of the bacitracin mix. The oxidation of the amino-thiazoline ring to the keto-thiazole ring to form bacitracin H and F...
Ngày tải lên: 14/03/2014, 23:20