báo cáo khoa học: " The function and mechanism of COX-2 in angiogenesis of gastric cancer cells" pdf

... vivo. Down-regulation of COX-2 inhibited angiogenesis of gastric cancer cells As shown in Figure 3, the number of endothelial cells within the tumors formed by COX-2- downregulating cells was less than that of tumors ... ecules in cells with decreased expression of COX-2. Results: Down-regulation of COX-2 could significantly inhibit the in vitro and in...

Ngày tải lên: 10/08/2014, 10:21

... ¼ X k i¼1 ðY i À ^ Y i Þ 2 s 2 Y i ð4Þ where Y i and ^ Y i are the measured and predicated satura- tions of the ith point, and k is the number of data points. Adair equation To determine the minimum number of interacting binding sites ... basic dimeric cooperon (the ab dimer in the case of verteb- rate Hb), in which cooperative interactions are allowed according t...

Ngày tải lên: 23/03/2014, 09:20

... reliable and accurate at the level of the individual patient remain to be identified. In this issue of Critical Care, Cox and coworkers [1] present interesting information on the outcomes of patients ... receiving prolonged mechanical ventilation (MV) in the intensive care unit (ICU). A tremendous increase in need for ICU care and associated expenditure is anticipate...

Ngày tải lên: 13/08/2014, 03:20

... and 4 (as defined by the staging classification of the International Federation of Gynecology and Obste- trics) consist about 2/3 of cases of epithelial ovarian cancer in the time of d iagnosis ... surgery. Introduction Ovarian cancer is the leading cause of morbidity and mortality among the gynecologic cancers [1]. Epithelial ovarian cancers consist 90% of...

Ngày tải lên: 09/08/2014, 03:21

... Domain 2 SLPI Trappin-2 Elafin A62D M63L Fig. 1. Schematic structure of protease inhibitors of the chelonianin family showing the domain organization, disulfide bond topology (plain line) and the ... together with a vast array of defense effector molecules, including the defensin and cathelici- din families of antimicrobial peptides. Many WAP- containing proteins that are n...

Ngày tải lên: 18/02/2014, 17:20

... >, of (––) DPH and (ÆÆÆÆ) TMA-DPH incorporated into spores of F. solani in the absence of VtA 3 (n) and in the presence of 1.5 l M VtA 3 (s )and3 lM VtA 3 (n). Insert in (B) shows the evolution of ... different types of cell, including animal, bacterial and fungal. The aim of this study was to obtain information on the cell targets and the mechanism...

Ngày tải lên: 19/02/2014, 07:20

... Fragments of HSQC and HMBC spectra of compound 1. Labels illustrate assignment of the amide linkage between the amino group of Asp and the carboxyl group of GalA residue E. Scheme 1. The structures of ... the identification of lipopolysaccharides and immunodeterminan ts in pathogenic strains of Haemophilis in u- enzae; application to clinical isolates. In M...

Ngày tải lên: 19/02/2014, 16:20

... result of the lost Ca 2+ ⁄ CaM-binding site of the IQ domain, but the missing PH1- and coiled-coil domains may also change the subcellular localization of this version of Ras- GRF1. These domains ... (F340) increases, whereas the fluorescence intensity at 380 nm (F380) decreases upon the binding of Ca 2+ . The change in the ratio of F340 ⁄ F380 determined the...

Ngày tải lên: 19/02/2014, 18:20

... dexamethasone and insulin, but in the presence of 10% (v/v) fetal bovine serum. We therefore investigated the effect of insulin on DAG molecular species composition using their culture condi- tions. In ... liver, and speak clearly against an involvement of phospholipases and PKC isoforms in hepatic insulin signalling, for the following reasons. First, we found that th...

Ngày tải lên: 20/02/2014, 02:21

... containing the double of NrfA subunit in respect to the NrfH subunit. Nevertheless, inside these huge aggregates there are species of the type a 2 b 2. The present findings are in agreement with the ... highlighted the role of Glu in the quinone/quinol site constitution. As the selected NrfH segment provides several amino acids fulfilling the above description, we...

Ngày tải lên: 21/02/2014, 00:20