báo cáo khoa học: " Microarray-based analysis of microRNA expression in breast cancer stem cells" doc

... Access Microarray-based analysis of microRNA expression in breast cancer stem cells Jian-guo Sun 1 , Rong-xia Liao 2 , Jun Qiu 1 , Jun-yu Jin 1 , Xin-xin Wang 1 , Yu-zhong Duan 1 , Fang-lin Chen 1 , ... studying breast can cer-initiating cells and developing therapeutic strategies aimed at eradicating the tumorigenic subpopulation of cells in breast cancer. Backgro...

Ngày tải lên: 10/08/2014, 10:20

... the profile of microRNAs expressed in the developing mouse brain. We observed a temporal wave of expression of microRNAs, suggesting that microRNAs play important roles in the development of the ... cited. Microarray analysis of microRNA expression in the developing mammalian brain<p>MicroRNAs are a large new class of tiny regulatory RNAs found in nematodes,...

Ngày tải lên: 14/08/2014, 14:21

... 7B and C). Effects of this deletion on growth of yeast cells were similar in strains containing mitochondrial group II introns and in strains lacking these introns. Accordingly, the ARM deletion ... were in the range of those determined for multicopy expression of wild- type Mrs2p. In contrast, expression of Mrs2-HA-F2 from a low-copy vector did not restore the rapid in...

Ngày tải lên: 23/03/2014, 10:21

... 3. Plot of k* cat and K* m against [I] 0 . (A) Effect of p-amindino- benzamidine concen tratio n on k à cat for autoactivation of trypsinogen by trypsin. (B) Effec t of p-amindinobenzamidine concentratio ... oncentrations of p-amindinobenzamidine. Figure 2B shows time courses for trypsinogen autoactiva- tion in the prese nce o f 100 l M p-amindinobenzamidine. As seen in this figure...

Ngày tải lên: 23/03/2014, 13:20

... of the domains occurs in several different ways, suggesting that the evolution of these proteins probably involved multiple gene duplication, gene fusion and domain swapping events. Members of ... activity was determined. Analysis of the protein expression pattern at both the tissue and subcellular level by microinjection of green fluorescent protein constructs revealed expres...

Ngày tải lên: 23/03/2014, 13:20

... tagging under different values of parameters. The parameters involved included the weight of transitional probability function, the number of sentences in an abstract, the minimal number of ... attention and become the mainstream of English for Specific Purposes, particularly in the field of English of Academic Writing (EAW). EAW deals mainly with genres, including r...

Ngày tải lên: 31/03/2014, 01:20

... [-]-1-methyl-2-[3-pyridyl]-pyrrolidine (nicotine) during maturation, air-curing, and storage of tobacco, as well as during combustion of cigarettes [13,14]. NNK induces lung tumors in rodents independent of the route of administration ... the source of total RNA for RT-PCR reactions. For the initial RT-PCR amplification of hprt mRNA, 4 µ l of the cell lysate was used in a...

Ngày tải lên: 07/08/2014, 18:20

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Ngày tải lên: 07/08/2014, 20:23

... squares interval mapping of QTL based on selective DNA pooling, Proceedings of the 27th International Confer- ence on Animal Genetics ISAG2000, 22–26 July, University of Minneapolis, Minneapolis, Minnesota. To ... particular drawback of DNA pooling estimation has been studied in detail in [11] and [17]. Adequate choice of sires, attending to the degree of presence of their m...

Ngày tải lên: 09/08/2014, 18:21

... graphed in figure 1. C. Isofemale strains maintained at a finite population size Inbreeding will increase divergence among isofemale strains if they are maintained at small ... strains using the inbree- ding coefficient F (FALCONER, 1981, p. 241) i.e., Isofemale strains expanded to an infinite population size have an inbreeding coefficient of 1...

Ngày tải lên: 09/08/2014, 22:22