báo cáo khoa học: " All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein" pdf

... al.: All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein. Journal of ... Access All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1...

Ngày tải lên: 10/08/2014, 10:20

... Whole-heart longitudinal sections are shown in (A) (magnifi- cation ·20; scale bars = 1 mm). The hemotoxylin and eosin-stained sections of the left ventricle are shown in (B) and Masson’s trichrome stained ... Transcriptional control of CYP2E1 in the perivenous liver region and during starvation. Biochem Biophys Res Commun 173, 331–338. 19 Thum T & Borlak J (2000) Gen...

Ngày tải lên: 22/03/2014, 16:20

... receptor dimerization and kinase activation [13,14]. The c -Kit expression distinguishes GISTs from tumors of smooth muscle cells. GISTs are the most common non-epithelial tumors of the GI tract. The diagnosis of ... Y, Shinomura Y, Kitamura Y: Gain -of- func- tion mutations of c -kit in human gastrointestinal stromal tumors. Science 1998, 279:577-580. 14. Miettine...

Ngày tải lên: 09/08/2014, 07:21

... Because the activity on X 6 remains the same upon engineering of the SBS of XBS, the results obtained in the previous screening experiment directly Table 1. The effect of genetic engineering of the ... stage. The screening procedure was performed on E. coli cell lysates containing (mutant) XBS and on P. pastoris expression media containing (mutant) XAN....

Ngày tải lên: 14/02/2014, 19:20

... experimental conditions. The phenomenon described by O’Donnell-Tormey might well take place in HepG2 cells. Impairment of the regulation of the extracellular content and the increase of its uptake induced ... levels and the sum of both). Even though the extracellular content increased in response to hypoxia, indicating release by the cells, the sum of bot...

Ngày tải lên: 18/02/2014, 16:20

... substrate. In the high salt conditions, the reaction mixture contained 1.58 m NaCl. The reaction was performed at 37 °C. After a 10 min preincubation in the absence of ATP, the reaction was initiated by ... probes inserted in the L1 and L2 loop upon binding of nucleotides and DNA. The fluorescence of modified Rad51 was measured after the addition of the ind...

Ngày tải lên: 19/02/2014, 06:20

... can express these features. We discuss the training and decoding of these classifiers in Section 5. Third, we choose among the analyses returned by the morphological analyzer by using the output of the ... chosen for the input word in training. 8 The ATB generates normalized forms of certain clitics and of the word stem, so that the resulting tokens are no...

Ngày tải lên: 20/02/2014, 15:20

... Translating colors in web site localisation. In In The Proceedings of Eu- ropean Languages and the Implementation of Com- munication and Information Technologies (Elicit). M. Bradley and P. Lang. ... emotion, obtaining a deeper understanding of the associations between colors, concepts and emotions may be helpful for many tasks in language understanding and gener-...

Ngày tải lên: 22/02/2014, 02:20

... possibil- ity of contamination by the other rZPGs and examined the sperm-binding activity and complex formation of these rZPGs. We also created deletion mutants of recombinant (r)ZP4 to examine whether ... complex-type chains have the strongest sperm-binding activity of the N-linked chains of ZP [30], and O-linked chains also have sperm-binding activity [31]....

Ngày tải lên: 07/03/2014, 05:20

... examined the interaction between FXa and sTF–FVII in a similar way by observing the impact of mutation in sTF on activation of FVII by FXa. The aim of the present work is to map in more detail the interaction ... is involved in binding to FXa in the complex, and FXa, most likely via its Gla domain, is also in contact with the Gla domain of FVIIa in...

Ngày tải lên: 17/03/2014, 03:20