Báo cáo y học: " “The non-ischemic repair” as a safe alternative method for repair of anterior post-infarction VSD" pptx

... STUD Y PROT O C O L Open Access “The non-ischemic repair as a safe alternative method for repair of anterior post-infarction VSDEfstratios E Apostolakis1, Antonios Kallikourdis2, Nikolaos ... beat empty of volume. The last part of the operation is carried outusing an off pump coronary artery bypass (OPCAB) sta-bilizer in order to perform the necessary distal coronaryanastomoses and ... Determinants and prognosis of myocardial damage aftercoronary artery bypass grafting. Ann Thorac Surg 2005, 79:837-45.9. Weisel R: Myocardial protection during for mechanical complications of myocardial...

Báo cáo y học: "An Avian Connection as a Catalyst to the 1918-1919 Influenza Pandemic"

... of the Journals of the American Medical Association. Influenza was not a reportable disease: the only evidence of the early occurrence was the registration of deaths reported as uncomplicated ... with both avian and human influenza A viruses. Human influenza viruses have been detected in pigs in Asia, Europe, and Africa [10]. Regions of the world such as Southeast Asia offer a close ... influenza virus is of animal origin and its infection of humans may date back as early as 2000 B.C.E. when humans began to domesticate animals. Hippocrates described an epidemic with “flu-like” symptoms...

Báo cáo y học: "Quantitative gait analysis as a method to assess mechanical hyperalgesia modulated by disease-modifying antirheumatoid drugs in the adjuvant-induced arthritic rat" pps

... The arthritisseverity score for each rat was calculated by adding thescores for each individual paw.Measurement of hind paw hyperalgesia and edemaThe method for measuring hyperalgesia has ... Rheumatol 1999, 17:553-560.40. Segawa Y, Yamaura M, Aota S, Omata T, Tuzuike N, Itokazu Y, OkaH, Tamaki H, Nakamura T: Methotrexate maintains bone massby preventing both a decrease in bone formation ... H37Ra (MT H37Ra;DIFCO Laboratories, Detroit, MI, USA) was used as an adju-vant to induce arthritis. Fresh adjuvant was prepared on thesame day as arthritis was induced. A volume of 0.1 ml of a...

Báo cáo Y học: Na+/K+-ATPase as a signal transducer Zijian Xie and Amir Askari docx

... 2435MINIREVIEWNa+/K+-ATPase as a signal transducerZijian Xie and Amir AskariDepartment of Pharmacology, Medical College of Ohio, Toledo, USANa+/K+-ATPase as an energy transducing ion pump hasbeen ... nontoxicconcentrations of ouabain that cause partial inhibition of Na+/K+-ATPase and an increase in cardiac contractility,also stimulate myocyte growth and protein synthesis, induce a number of early response ... Using partiallyinhibitory concentrations of ouabain, activation of parts orall of the pathways that begin with protein tyrosinephosphorylation and lead to ROS generation and MAPKactivation...

Báo cáo sinh học: "The THO complex as a key mRNP biogenesis factor in development and cell differentiation" potx

... and poly-adenylation factors [10].Function of THO in development and diﬀerentiatione relevance of THO in cell physiology has been clearly shown from yeast to humans. Yeast THO null mutants ... co-transcriptional action of THO in higher eukaryotes [9]. e impact of THO in RNA physiology, however, may go beyond transcription elongation and its asso cia-ted RNA metabolism steps, as shown by the ... complex exists as a salt-resistant stable complex independent of UAP56 and Yra1 [4,5].In yeast, THO binds to active chromatin in an RNA-independent manner. A plausible scenario is as follows (Figure...

Báo cáo y học: "The Factors Influencing Depression Endpoints Research (FINDER) study: final results of Italian patients with depressio" docx

... that somatic symptom-associated disability and a number of somatic symptomsare strongly associated with increased depression sever-ity and health resource use, as well as with decreasedquality ... 9:33http://www.annals-general-psychiatry.com/content/9/1/33Page 2 of 9Another result of our study indica tes that a higherseverity of somatic and painful symptoms at base line, as evaluated by patients, was associated with ... the analysis (0.2%) due to failure to meet entrycriteria. Data were analysed using SAS V.8.2 (SAS, Cary,NC, USA).Loss to follow-up analysisNo predictive analysis was performed for the Italiansubset....

Báo cáo y học: "The P2X7 receptor is a candidate product of murine and human lupus susceptibility loci: a hypothesis and comparison of murine allelic products" potx

... belongs to a category that bears many of the hall-marks of 'classic' caspase-dependent apoptosis, but alsoto other categories such as cytoplasmic vacuolization moreoften associated with ... rheumatic diseases. Clin Rheumatol1999, 18:28-32.15. Ren Y, Tang J, Mok MY, Chan AW, Wu A, Lau CS: Increasedapoptotic neutrophils and macrophages and impaired macro-phage phagocytic clearance ... the cycle of ATPrelease and destruction. Release of autoantigens withinP2X7-stimulated aponecrotic debris may also contribute to a breakdown in self-tolerance and initiation of autoimmunity.While...

Báo cáo y học: "The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes" ppt

... 5'-ACCCAAAACACAACTCTTCGG-3'IL-1Rrp2 (B) F: 5'-AGCAAAATCCCAGTGTCCAAA-3' 60 147 [AF284434]R: 5'-GGTTTACATGTATTCTATGACAG-3'IL-1F8 F: 5'-ACCAAGGAGAGAGGCATAACTAAT-3' ... 5'-AGTGAACTCAGTCGCATAATGATC-3'IL-1β F: 5'-GCTGAGGAAGATGCTGGTTC-3' 57 146 [NM000756]R: 5'-GTGATCGTACAGGTGCATCG-3'β-actin F: 5'-CCAAGGCCAACCGCGAGAAGATGAC-3' ... oxide was assessed, as Table 1Summary of primers usedcDNA Forward and reverse primers Ta (°C) Product (bp) GenBankIL-1Rrp2 (A) F: 5'-AGCAAAATCCCAGTGTCCAAA-3' 60 291 [AF284434]R: 5'-ACCCAAAACACAACTCTTCGG-3'IL-1Rrp2...

Báo cáo y học: " The RNA interference pathway: a new target for autoimmunity" pot

... RNAimachinery is that RNAi was initially recognized as an antiviralmechanism in plants and certain invertebrates [14]. Theevolutionary conservation of RNAi suggests a similar role for RNAi in mammals, which ... molecular modifications. Thediversity of autoantibody specificities and their associationwith particular diseases may be related to the combination of genetic and environmental factors that are ... Although they wereinitially reported to be specifically associated with systemiclupus erythematosus [7], a later study showed that auto-antibodies to the Su antigen are found in a variety of systemicrheumatic...

Báo cáo y học: "Decreased metalloproteinase production as a response to mechanical pressure in human cartilage: a mechanism for homeostatic regulatio" pps

... collagen in OF and OA cartilageAnalysis of aggrecan and type II collagen in OF and OA cartilage. Ratio of aggrecan to type II collagen in the cartilage matrix of OA and OF femoral heads and ... 5Quantification of apoptosis in OF and OA cartilageQuantification of apoptosis in OF and OA cartilage. Quantification of apoptosis. Percentage of apoptotic cells measured by flow cytometry of ... aggrecan totype II collagen was determined by ELISA. This ratio allowsnormalisation of data and elimination of variability due to carti-lage quality, cartilage wet weight, and experimental variation.Significant...

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