... antibiotics, both topicallyand systemically administered, may be completely different in other settings. Therefore, extrapolation of the resistancefindings to ICUs in other countries may be dangerous. ... challenging, but toomany questions regarding the epidemiology of these bacteriaremain unanswered to draw firm conclusions. Also, in terms of development of resistance, the time frame of the study ... that anyintervention may, unwillingly, change clinical practice. Justemphasizing the correct use of SDD may have improvedcompliance with hygienic measures. In fact, this indirecteffect of SDD...