Báo cáo y học: "Beneficial effect of the oxygen free radical scavenger amifostine (WR-2721) on spinal cord ischemia/reperfusion injury in rabbits" docx

... Acute spinal cord injury management and surgical consideration: Acute medical management of spinal cord injury: Pharmacologic management of spine inju- ries. In Lin Spinal Cord Medicine. Principles ... detection has an acting-time limitation of 75 minutes. As the positive results of the effectiveness of Amifostine as scavenger of free radicals in spin...

Ngày tải lên: 10/08/2014, 10:20

... (Figure 2b). In contrast, STA-5326-treated mice exhibited some inflammatory cell infiltration into the vitreous cavity, but only a few infiltrating cells in the retina with retinal layers remaining intact ... results clearly indicate that oral administration of SAT-5326 is effective in suppress- ing inflammation in EAU. IL-17 production and the proportion of IL-17-producing...

Ngày tải lên: 09/08/2014, 13:22

... observed. The positive clinical effects that HBO 2 has in the treatment of chronic inflammation may relate to its effects on secretion of IL-1, IL-6, and TNF-a. The effects of HBO 2 on prostaglandin, ... cytokines involved in wound pathophysiology and inflammation in particular were recently reviewed [8]. That review indicates that HBO 2 has important effects on the...

Ngày tải lên: 11/08/2014, 17:21

... virion production and infectivity. Influence of SR proteins on virion production and infectivity This was examined by monitoring the levels of HIV-1 vir- ion production under conditions of increasing ... RNA. Alterations of HIV-1 splicing pattern by SR proteins modify viral protein synthesis The profound modifications of the HIV-1 splicing pattern by overexpression of on...

Ngày tải lên: 13/08/2014, 09:21

... expression of interferon-γ was higher in the vaccinated mice than in the controls. Reduced infiltration of inflammatory cells and the prominent infiltration of CD8+ T cells were observed in histology ... detected in the lungs of the control mice (Fig. 2d). In the immunohis- Effect of genetic vaccination on lung histopathology in an animal model of aller...

Ngày tải lên: 13/08/2014, 13:22

... other and to full length ASC in respect to their function as an inflammasome adaptor, with one of the isoforms even showing an inhibitory effect. Consistently, only the activating isoforms of ... expression experiments, is only tem- porarily expressed, or is not induced by the tested pro- inflammatory stimuli, but rather by anti-inflammatory stimuli during the resolution of...

Ngày tải lên: 11/08/2014, 03:20

... RT-PCR of the enzymes involved in the synthesis of these mediators (cyclooxygenase-2 (COX-2) and inducible Figure 1 Cytokine circulating levels in mice at the end of treatment in the collagen-induced ... greatly reduces the local expression of both these cytokines in the joints of arthritic mice, which may account for the block in joint erosion induced in...

Ngày tải lên: 09/08/2014, 06:23

... Liu L. The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression. J Biol Chem ... [15, 18]. Most of them are located near the N-terminal portion of the proteins followed by zinc-fingers, and are involved in the reg- ulation of cell division and differen...

Ngày tải lên: 25/10/2012, 11:15

... imaging probe which is used as the real-time imaging unit of the system, guiding the target tissue volume, monitoring the energy deposition and the therapeutic effect, and also controlling the ... efficacy and safety. To evaluate the rela- tionship between HIFU energy and pancreas histol- ogy, a preclinical in vivo study was conducted in swine demons t rat ing the f...

Ngày tải lên: 25/10/2012, 11:18

... mechanical dyssynchrony. These findings may further explain why patients with normal QRS duration may benefit from cardiac re- synchronization whether or not they have mechanical dyssynchrony under ... reducing LV dyssynchrony and thereby liber- ating a further segment of the RR interval for diastole (24). Considering that direct evaluation of LV dyssynchrony is still complex and t...

Ngày tải lên: 05/11/2012, 11:32