Báo cáo y học: "Gene polymorphisms in APOE, NOS3, and LIPC genes may be risk factors for cardiac adverse events after primary CABG" pdf

... article Gene polymorphisms in APOE, NOS3, and LIPC genes may be risk factors for cardiac adverse events after primary CABG Sandra Eifert* 1 , Astrid Rasch 1 , Andres Beiras-Fernandez 1 , Georg ... of risk factors have become the basis for sec- ondary CAD prevention after primary coronary artery bypass grafting (CABG). Appearance of cardiac advers...

Ngày tải lên: 10/08/2014, 10:20

... environmental factors inter- act in RA pathogenesis, and suggest that heavy cigarette smok- ing and PTPN22 may be acting in a similar mechanistic pathway. Competing interests The authors declare that they ... study are slightly different from ours, in that they did not find a significant interaction between the presence of the PTPN22 polymorphism and smoking in determining...

Ngày tải lên: 09/08/2014, 10:23

... harbo uring the chitinase 3-like 1 (CHI 3L1) gene encoding the YKL-40 protein [6]. YKL- 40 is a 40 kDa heparin- and chitin-binding glycoprotein, and a member of chitinase like proteins. YKL-40 ... healthy subjects, and YKL-40 has been suggested to be an auto-antigen and may play a role in development of RA and in inflammation. Methods: Eight SNPs in the CHI3L1 gene and p...

Ngày tải lên: 12/08/2014, 17:22

... common polymorphisms in DNA repair genes are continuously being identified, and these polymorphisms may play a pivotal role in sporadic carcinogenesis. A growing body of literature, including ... important for maintaining DNA integrity and preventing carcinogenesis. Recent lung cancer studies have focused on identifying the effects of single nucleotide polymorphisms (S...

Ngày tải lên: 31/10/2012, 14:59

... antigen-specific lymphocytes has major consequences for the inflammatory process, and inhibition of angiogenesis results in reduced pannus formation and synovial hyperplasia. The numbers in brackets indicate ... and in CIA in rhesus monkeys, respectively [84,85]. Subsequent treat- ment with intravenous ganciclovir increased apoptotic cell death in the synovium and cytolysi...

Ngày tải lên: 09/08/2014, 01:24

... gen- uine associations because they have been found in a hypoth- esis driven case-control study and have shown modest effects, in the range that is expected in complex diseases and specifically in ... support to this hypothesis and will show how important it is to define the participation of each ECM protease in joint pathology before trying to manipulate them therapeutically....

Ngày tải lên: 09/08/2014, 07:20

... profiles in rheumatoid fibroblast-like synoviocytes induced by the proinflammatory cytokines inter- leukin-1 beta and tumour necrosis factor. Inflamm Res 2005, 54:10-16. 42. Zhou A, Scoggin S, Gaynor ... previously described [21], and the resulting, labelled cDNAs were imme- diately used for hybridisation. Transcriptome analysis and qRT-PCR Our array covering 12,000 cDNA probes for...

Ngày tải lên: 09/08/2014, 08:22

... Huang YK, Chen YT, Hsueh YM: Urinary 8-hydroxydeoxyguanosine and urothelial carcinoma risk in low arsenic exposure area. Toxicol Appl Pharmacol 2008, 226:14-21. 19. Huang YL, Hsueh YM, Huang YK, Yip ... capacity may be an important risk- modifying factor for arsenic-induced health effects. Inefficient methylation of arsenic has been documented to be a sig- nificant modifier fo...

Ngày tải lên: 10/08/2014, 05:21

... white and continued to smoke during the 5-year period of the LHS. These subjects were genotyped for polymorphisms in α1- antitrypsin, mEH, vitamin D binding protein, and TNF-α and TNF-β genes. TNF-β ... association between a poly- morphism and disease exists can be greatly improved by studying a more narrowly defined intermediate phenotype. In the case of asthma, intermedia...

Ngày tải lên: 12/08/2014, 18:20

... to be included in the risk assessment regarding possible major incidents in this region. The purpose of this study was to find whether this institution has achieved its primary tasks by analyzing ... planning, teaching and training responsibilities offers possibilities for planning, teaching and training disaster medicine by giving immediate feed- back based on real incidents....

Ngày tải lên: 25/10/2012, 09:56