... H, Ding R, Ji FY, KanbaraN, Kuzume H, Sanbo M, Yagi T, Obata K: Mice lacking the 65 kDa isoform of glutamic acid decarboxylase (GAD65) maintainnormal levels of GAD67 and GABA in their brains ... AccessResearchHypercapnic ventilatory response in mice lacking the 65 kDa isoform of Glutamic Acid Decarboxylase (GAD65)John M Bissonnette*1,2 and Sharon J Knopp1Address: 1Departments of Obstetrics ... week of age, followedby a return in sensitivity. A second abnormality is seen at postnatal day 5 (P5) rats in that theycannot maintain the increase in frequency for 5 min of hypercapnia. In mice...