Báo cáo y học: "Pu-Erh tea and GABA attenuates oxidative stress in kainic acid-induced status epilepticu" docx

... acid (GABA) and statin [7,8 ]. GABA metabolism in substan- tia nigra (SN) plays a key role in seizur e arrest. When seizures stop, a major increase in GABA synthesis in postictal S N. GABA synthesis ... 10 Discussion The main result of the present study is the finding PETL and GABA protected animals from KA-induced brain injury. MDA and apoptosis w ere significantly red...

Ngày tải lên: 10/08/2014, 10:20

... produced predominantly by activated macrophages and lymphocytes mediate many inflamma- tory processes [49]. These proinflammatory cytokines include interferon-γ (IFN-γ), interleukin-1 (IL-1), tumour necrosis ... purposes) induce local injury and participate in the orchestration of systemic inflammation and all of its consequences. ICAM- 1 in particular plays a role in inflammatory...

Ngày tải lên: 12/08/2014, 18:21

... proteins, is hydrolysed in an insulin- dependent manner to produce an inositolphosphoglycan and d iacylglycerol [52]. The inositolphosphoglycan a ppears to mediate metabolic effects of insulin by ... GPI-anchored ephrin-A5 in lipid rafts. The ephrin-A5 induced signalling results in increased tyrosine phosphorylation of several raft proteins and recruitment of the Src family kinase F...

Ngày tải lên: 31/03/2014, 21:21

... study of psycho- metrics and case finding abilities in general practice. BMC Psy- chiatry 2005, 5:46.:46. 24. Lewis G: Observer bias in the assessment of anxiety and depression. Soc Psychiatry ... participated in data collection, KF participated in data collection and processing, PP participated in data collec- tion and processing, KP participated in data collection and...

Ngày tải lên: 08/08/2014, 23:20

... autoimmune disease. Interestingly, although GPI is ubiquitously expressed in the body, the immune response against GPI appears to initiate in the draining lymph nodes of peripheral joints in K/B×N mice ... is currently unclear why systemic autoreactivity against the ubiquitously expressed glycolytic enzyme G6PI specifically induces arthritis, with no other symptoms of organ-specific or...

Ngày tải lên: 09/08/2014, 06:22

... articular cartilage. The increased frequency of osteo- arthritis with aging indicates the complex etiology of this disease, which includes pathophysiology and joint stability including biomechanics. ... response including osteophyte formation and joint capsule thickening. The etiology of osteoarthritis remains unknown. At steady state the homeostasis and response of articular cartilage...

Ngày tải lên: 09/08/2014, 07:20

... we investigated the MAP kinase and IκB kinase signaling pathways by western blot (Figure 3a). Interestingly, piperine did not significantly affect the IκB kinase signaling pathway or the MAP kinase ... C, Lee YA, Hong SJ, Lee SH, Yang HI, Yoo MC: Taurine chloramine differentially inhibits matrix metalloproteinase 1 and 13 synthesis in inter- leukin-1β stimulated fibroblast-like synovioc...

Ngày tải lên: 09/08/2014, 14:20

... time, although only three such lineages were included in this survey. Other than hatching (and the conditions immediatel y preceding hatching), sexual sub- lines were maintained in the same manner ... Genomics and Bioinformatics at Indiana University, which is supported in part by the METACyt Initiative of Indiana University, funded in part through a major grant from the Lilly En...

Ngày tải lên: 09/08/2014, 20:21

... 447:913. 105. Yutin N, Wolf MY, Wolf YI, Koonin EV: The origins of phagocytosis and eukaryogenesis. Biol Direct 2009, 4:9. 106. Martin W, Koonin EV: Introns and the origin of nucleus-cytosol compartmentation. ... yielded many insights into the origin and earliest stages of evolution of eukaryotes. Recent fi ndings indicate that several key cellular systems of eukaryotes exist in a...

Ngày tải lên: 09/08/2014, 20:21

... circulating cell types (neutrophils and monocytes) can occur. A study by Wiik (2001) has demonstrated that abdominal surgery causes an increase in neutrophil and monocyte counts along with lymphocytopenia ... significant increase in the leuko- cyte elastase levels were displayed from baseline (preoperatively) up to day 1 post-surgery following TKR, with levels decreasing at day 3 and...

Ngày tải lên: 11/08/2014, 08:22