Báo cáo y học: " Induction of apoptosis and inhibition of cell growth by tbx5 knockdown contribute to dysmorphogenesis in Zebrafish embryos" pptx

... Lu et al.: Induction of apoptosis and inhibition of cell growth by tbx5 knockdown contribute to dysmorphogenesis in Zebrafish embryos. Journal of Biomedical Science 2011 18:73. Submit your next ... 18:73 http://www.jbiomedsci.com/content/18/1/73 Page 4 of 10 RESEARC H Open Access Induction of apoptosis and inhibition of cell growth by tbx...

Ngày tải lên: 10/08/2014, 10:20

... phosphorylation of the C-terminus of R* and binding by arrestin. Phosphorylation somewhat decreases the ability of R* to signal transducin. Rapid shut- off of R* signalling is then accomplished by binding of arrestin ... of arrestin to photoactivated phosphorylated rhodopsin (R*P [2–5]). Arrestin plays a critical role in visual signalling by completely blocking the a...

Ngày tải lên: 22/02/2014, 07:20

... found in various proteins. This domain is a part of the nidogen glycoproteins, which are expressed by mesenchymal and epithelial cells. Nidogens have a high affinity for laminin- binding protein and ... molecular mass glycoproteins synthesized by secretory epithelia. All mucins have a large domain composed of tandemly repeated sequences rich in serine and threonine residues t...

Ngày tải lên: 08/03/2014, 23:20

... degÆcm 2 Æ dmol )1 for fibritin B1 and fibritin SM4, respectively. Interestingly, fibritin M e xhibited more a helicity than fibritin E, probably due to the absence of insertion loops. The CD spectrum of fibritin F represented ... wild-type fibritin, can be explained mainly by two residues substitutions. As confirmed by X-ray crystallography [9] , the mutation Ser421 to Lys created a n...

Ngày tải lên: 24/03/2014, 03:21

... was stopped by addition of 1 mL of copper reagent (Somogyi reagent) and boiling for 5 min. Liberated glucose was measured by the Somogyi-Nelson method [34]. To study stability in relation to temperature, ... activity was analyzed by measuring the amount of glucose released from laminarin. Standard assays (0.25 mL) were in 20 m M sodium acetate buffer, pH 4.5, and conta...

Ngày tải lên: 24/03/2014, 04:21

... mostly diplomas in general and psychiatric nursing, and they had been working in their various areas of specialty for at least 1 year. The study was a point survey of opinions of healthcare workers ... workers was often based on the theory of insult to the developing brain, either as a result of maternal infection, intrauterine infection or physical trauma to the brain f...

Ngày tải lên: 08/08/2014, 23:21

... Specifically, a number of studies report an increased risk of subsequently developing MDD among non-depressed individuals complaining of insomnia (that is, insomnia may represent a prodromal symptom) [5,6]. ... found to be significant independent predictors of early recurrence across treatment groups. Identifying predictors of relapse in MDD is potentially clinically relevant, s...

Ngày tải lên: 08/08/2014, 23:21

... cells in a wide range of arthritis types and suggested that this finding might be the consequence of reduced inflam- matory cell trafficking to the joints [15]. However, apoptosis induction by ... Exposure of cells to proinflammatory stimuli such as TNF and IL-1 can lead to induction of -isoform of human glucocorticoid receptor (hGR) and suppression of hG...

Ngày tải lên: 09/08/2014, 01:22

... surface of CD4 + CD28 – T cells may be involved in a HLA-B27 mediated co-stimulation of these proinflammatory and cytotoxic cells. Keywords: ankylosing spondylitis, CD28 molecule, CD4 + T cells, cytotoxicity, ... independent of age and duration of ankylosing spondylitis. CD4 + CD28 – T cells produce IFN-γ and perforin, and thus they must be considered proinflammatory and c...

Ngày tải lên: 09/08/2014, 01:23

... costimulatory molecules, elevated production of cytokines, and increased T cell stimulatory capacity before and after the onset of the disease [14]. In our study we analyzed DCs in the original NZM2410 ... induce peripheral tolerance [25] unless they receive an activation sig- nal, such as CD40 triggering, that induces the production by DCs of large amounts of pro-inflamma...

Ngày tải lên: 09/08/2014, 07:20