... Gly23 of birtoxin (Fig. 4). In ikitoxin the presence of Glu23 chargepreceding the a-helix modifies the activity of this toxin in aunique way to result in reduced potency in mice. The C-termini of ... which the symptomsfaded and the mice completely recovered. Ikitoxin did notshow lethality during the course of the observation period in the range of injected doses. Activity against insects ... steady-state inactivation, respectively, in one cell. E,F and G,H show the effect of ikitoxin on the same properties in a different cell. The traces in the upper row of A, C, E and G are the membrane...