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Báo cáo y học: "Mesenchymal stem cell transplantation ameliorates motor function deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cell" ppsx

Báo cáo Y học: Bax-induced cell death in yeast depends on mitochondrial lipid oxidation doc

Báo cáo Y học: Bax-induced cell death in yeast depends on mitochondrial lipid oxidation doc

... stronglysupport the hypothesis that Bax-induced lipid oxidation isdirectly related to Bax-killing efficiency. Bax-induced lipid peroxidation is poorly relatedto Bax-induced ROS productionMadeo ... supporting further thehypothesis that Bax actually induces lipid peroxidation. Mitochondrial lipid oxidation is involved in cell death kineticsChatterjee et al. [32] showed that the unsaturation index ... Bax-induced death. Taken together,these results show that Bax-induced mitochondrial lipid oxidation is relevant to Bax-induced cell death. Conversely, lipid oxidation is poorly related to the massive Bax-induced superoxide...
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Báo cáo sinh học: "Cancer stem cell subsets and their relationship" pot

... Winslet M, Seifalian A: Stem cells and cancer: an overview. Stem Cell Rev 2007, 3(4):249-55.4. Huntly B, Gilliland D: Leukaemia stem cells and the evolution of cancer- stem- cell research. Nat Rev ... exists and every single cancer cell has the capacity of initiation and progression. Cancer stem cell hypothesis suggests thattargeted therapy to cancer stem cells, not cancer TA cells and cancer ... Cancer stem cells are hierarchical populations that consist of precancerous stem cells, primary cancer stem cells, migrating cancer stem cells and chemoradioresistant cancer stem cells,playing...
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báo cáo hóa học:

báo cáo hóa học:" Cancer stem cell subsets and their relationships" pot

... of cancer stem cells. Thus we propose a horizontal hierarchy that com-prises precancerous stem cells, primary cancer stem cells, migrating cancer stem cells and chemoradioresis-tant cancer stem ... unclear.Relationships among cancer stem cell subsets Up to now, precancerous stem cells, primary cancer stem cells and migrating cancer stem cells have been provento exist in the progression of cancer [45,52,61,62], ... Cancer stem cells are hierarchical populations that consist of precancerous stem cells, primary cancer stem cells, migrating cancer stem cells and chemoradioresistant cancer stem cells,playing...
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Báo cáo sinh học:

Báo cáo sinh học: "The ‘stem cell’ concept: is it holding us back" pptx

... reconstitution. These and other studies gave us a good and enduring operational definition for stem cells: those cells that when introduced OpinionThe ‘stem cell’ concept: is it holding us back?Arthur ... burning - but it happens that no substance with definite physical charac-teristics has ever been found that satisfies this operational definition. Indeed, it was ultimately the discovery that ... consider ‘phlogiston’, an idea introduced in the seventeenth century to explain the process of combustion. The concept of phlogiston admits precise operational definition - it is the substance...
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Báo cáo y học: "Hematopoietic stem cell transplantation for systemic lupus erythematosus" ppsx

... for severe systemic lupus erythematosus of long duration. Lupus 1997, 6:545-548.2. Burt RK, Traynor A, Ramsey-Goldman R: Hematopoietic stem- cell transplantation for systemic lupus erythematosus. ... transplantation: a phase I study. Lancet 2000, 356:701-707.4. Traynor A, Burt RK: Haematopoietic stem cell transplantation for active systemic lupus erythematosus. Rheumatology 1999,38:767-772.5. ... Traynor AE, Schroeder J, Rosa RM, Cheng D, Stefka J, Mujais S,Baker S, Burt RK: Treatment of severe systemic lupus erythe-matosus with high-dose chemotherapy and haemopoietic stem- cell transplantation: ...
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Báo cáo y học: "Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome" pot

... out NK cytotox-icity assays and manuscript preparation. EHG carried outstatistical analysis and manuscript preparation. TBG car-ried out patient referral, clinical data analysis and manu-script ... http:/ /arthritis- research.com/content/7/1/R30R30Vol 7 No 1Research articleNatural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage ... autoimmunedisease. Autoimmunity 2002, 35:1-14.29. Yabuhara A, Yang FC, Nakazawa T, Iwasaki Y, Mori T, Koike K,Kawa H, Komiyama A: A killing defect of natural killer cells as anunderlying immunologic abnormality...
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Báo cáo y học: "Altered dendritic cell distribution in patients with common variable immunodeficiency" pot

... lymphocytes of patients with com-mon variable immunodeficiency (CVI) produce reduced levelsof interleukin-4, interleukin-2 and interferon-gamma, but pro-liferate normally upon activation by ... for dendritic cells (DCs) in the generation of immunoglobulin-secreting plasma cells. In thework reported herein, we analyzed the frequency of peripheralblood plasmacytoid DCs (pDCs) and myeloid ... ofchemokine receptors by plasmacytoid dendritic cells. JImmunol 2001, 167:1862-1866.18. Bayry J, Lacroix-Desmazes S, Kazatchkine MD, Galicier L, Lepelle-tier Y, Webster D, Lévy Y, Eibl MM,...
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Báo cáo y học: "Celastrus aculeatus Merr. suppresses the induction and progression of autoimmune arthritis by modulating immune response to heat-shock protein 65" pptx

... ananti-inflammatory type [26]. This relative deviation of the cytokine response, caused either by decreased Th1-typecytokines and/ or by enhanced Th2-type cytokines leading to the regression of an autoimmune ... anti-inflammatory cytokines over pro-inflammatory cytokines in response to Bhsp65 To test and compare the T cell proliferative and cytokine response to the disease-related antigen Bhsp65 of Celastrus-treated ... treatmentfacilitated the secretion of the anti-inflammatory cytokine IL-10over the pro-inflammatory cytokine IFN-γ, resulting in the over-all skewing (immune deviation) of the cytokine response to ananti-inflammatory...
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Báo cáo y học:

Báo cáo y học: "Mesenchymal stem cells in arthritic disease" pot

... cardiac injuries, at least partially by shifting themicroenvironment at the injury sites from proinflammatory toanti-inflammatory [55-57]. In a murine pulmonary fibrosismodel, MSCs inhibited ... charac-terized in vitro by their extensive proliferative ability in anuncommitted state while retaining the potential todifferentiate along various lineages of mesenchymal origin,including chondrocyte, ... delivered via either adenoviral infection orosmotic pumps in inhibiting bleomycin-induced increases in TNF-α, IL-1α, and trafficking of lymphocytes and neutrophilsinto the lung [56]. These successful...
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Báo cáo y học: "Mesenchymal progenitor cell markers in human articular cartilage: normal distribution and changes in osteoarthritis" ppt

... Sox9 staining patterns were mainlynuclear in normal cartilage (Figure 2), but Sox9 staining in OAclusters was present in both the cytoplasm and nucleus, orFigure 3Stem cell markers in human ... (OA) articular cartilageStem cell markers in human osteoarthritis (OA) articular cartilage. (a) Safranin O and Notch-1 staining in clusters (10ì and 40ì). (b) Safranin O and Stro-1 staining of ... mesenchymal stem cells (MSCs) and stromal cells. J Cell Physiol 1998, 176:57-66.22. Saalbach A, Haustein UF, Anderegg U: A ligand of human thy-1is localized on polymorphonuclear leukocytes and...
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Báo cáo y học: "Mesenchymal stem cell transplantation ameliorates motor function deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cell" ppsx

... cell transplantation ameliorates motor function deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cells. Journal of Biomedical Science 2011 18:54.Submit your next manuscript ... deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cellsYou-Kang Chang1,2,3, Ming-Hsiang Chen4, Yi-Hung Chiang1,5, Yu-Fan Chen4, Wei-Hsien Ma4, Chian-You Tseng4,Bin-Wen ... transplanta-tion of hMSCs via tail vein could ameliorate the dete-rioration of motor function in SCA2 transgenic mice.Rescue of Purkinje Cells by Transplanted hMSCsLoss of PCs had been noted by immunohistochemicalstain...
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Báo cáo y học: "Mesenchymal stem cells avoid allogeneic rejection" pptx

... Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes,but not activated cytotoxic T lymphocytes or natural killer cells. Transplantation 2003, 76:1208-1213.60. Dormady SP, Bashayan ... AccessReviewMesenchymal stem cells avoid allogeneic rejectionJennifer M Ryan1, Frank P Barry2, J Mary Murphy2 and Bernard P Mahon*1Address: 1Institute of Immunology, National University of Ireland, ... Ireland, Galway, IrelandEmail: Jennifer M Ryan - JENNIFER.M.RYAN@nuim.ie; Frank P Barry - frank.barry@nuigalway.ie; J Mary Murphy - mary.murphy@nuigalway.ie; Bernard P Mahon* - bpmahon@nuim.ie*...
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Báo cáo y học:

Báo cáo y học: " Mesenchymal stem cells in autoimmune diseases: hype or hope" ppt

... underlying the possible in vivo immuno modulatory eff ects of MSCs remain a critical and unresolved question. By comparing side by side the eff ects of MSCs in vitro and in vivo, the study by ... Diaz F, Inostroza C, Rojo D, Mönckeberg G, Figueroa FE: Autologous mesenchymal stem cell treatment increased T regulatory cells with no e ect on disease activity in two systemic lupus erythematosus ... Immunomodulatory properties of mesenchymal stromal cells. Blood 2007, 110:3499-3506.3. Nauta AJ, Westerhuis G, Kruisselbrink AB, Lurvink EG, Willemze R, Fibbe WE: Donor-derived mesenchymal stem cells...
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Báo cáo y học: "Mesenchymal stem cell derived hematopoietic cells are permissive to HIV-1 infection" pptx

... tissue derived mesenchymal stem cells; HD: hematopoietic differentiated cells; AIDS: acquired immunedeficiency syndrom e; HAART: highly active anti-retroviral therapy; HPCs: hematopoietic progenitor ... fusion to cellular membranes, thusfacilitating entry into hematopoietic cells [4]. Althoughthe peripheral blood -derived hematopoietic progenitor cells (HPCs) can express the HIV-1 co-receptors ... established as to howthese mesenchyme derived cells be come susceptible to HIV-1 and whether their HIV-1 production rates are comparable to that observed in HIV-1 i nfected lym-phoid or myeloid cells. ...
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Báo cáo y học: "Tat RNA silencing suppressor activity contributes to perturbation of lymphocyte miRNA by HIV-1" ppsx

... Tat RNA silencing suppressor activity contributes to perturbation of lymphocyte miRNA by HIV-1. Retrovirology2011 8:36.Submit your next manuscript to BioMed Centraland take full advantage of: ... in miRNA profile is observed by ablation of Vpr/VifThe possibility that HIV-1 manipulation of host miRNA contributes to HIV-1 induced cell cycle delaywas posited by the prominent role of miRNA ... 13 RESEARCH Open AccessTat RNA silencing suppressor activity contributes to perturbation of lymphocyte miRNA by HIV-1Amy M Hayes1, Shuiming Qian1,2, Lianbo Yu3and Kathleen Boris-Lawrie1,2*AbstractBackground:...
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