Báo cáo y học: "Early innate immune events induced by prolonged cold ischemia exacerbate allograft vasculopathy" potx

... ARTIC L E Open Access Early innate immune events induced by prolonged cold ischemia exacerbate allograft vasculopathy Jennifer J Devitt 1* , Chelsey L King 2 , Timothy DG Lee 1,2,3 , Camille L ... Libby P, Pober JS: Chronic rejection. Immunity 2001, 14(4):387-97. doi:10.1186/1749-8090-6-2 Cite this article as: Devitt et al.: Early innate immune events induced by...

Ngày tải lên: 10/08/2014, 09:23

... phenotype in early RA synovial fluid. The role of the Th2-type cytokines in early RA is unclear. IL-4 has divergent proinflammatory and anti-inflammatory effects in Figure 4 Longitudinal synovial ... early synovitis that develops into rheumatoid arthritis (RA); 2, early synovitis that develops into non-rheumatoid persistent synovitis; 3, early non-crystal-related resolving synovitis; 4, crys...

Ngày tải lên: 09/08/2014, 06:22

... spillover or cytotoxicity was induced by EGFP expression. The mitochondrial depolariza- tion mediated by httEx1-103Q-EGFP expression was more drastic and was roughly similar to that induced by a 15 ... procedures). No alteration of the chymotrypsin-like activity was induced by httEx1-25Q-EGFP expression, and only a slight decrease (about 10%) was induced by httEx1- 72Q-EGFP...

Ngày tải lên: 19/02/2014, 06:20

... directly. PKC is activated by diacylglycerol, which is formed by phospholipase C (PLC) mediated phosphatidylinositol 4,5-diphosphate cleavage. PLC in turn is activated by binding to intracellular ... potential use for radiation induced gene therapy as recently reported [9,29]. While it is ®rmly established, that the Egr-1 promoter is effectively and quickly activated by growth facto...

Ngày tải lên: 17/03/2014, 17:20

... regulatory T cells. The review will address the induction of the three types of regulatory T cells, the mechanisms by which they suppress T-cell responses in the periphery, the role they play in immune ... LR, Kemeny DM, Bowen G, Rook G, Walker C: Suppression of airway eosinophilia by killed Mycobacterium vaccae -induced allergen-specific regulatory T-cells. Nat Med 2002, 8:625-629. 34...

Ngày tải lên: 09/08/2014, 01:24

... By improving RNA yields from small cartilage samples and selecting highly sensitive methods for quantitative gene expression analysis, we studied alterations in chondrocyte metabolism side by ... levels between any of the study groups (controls, ACLT, loca- tions, time). Analysis of tenascinC and the chitinase-like molecules YKL39 and YKL40 was included in the present study because they h...

Ngày tải lên: 09/08/2014, 06:22

... at any body site. Analysis of oedema by body site, or hypertension by subcate- gory, was not carried out, as event numbers were too low for practicable analysis. Trial quality and validity Three ... [10,11] are likely to apply to cyclooxygenase-2 selective inhibitors. Endoscopically detected ulcers were affected both by whether celecoxib or NSAID was used, and by whether or not prophy...

Ngày tải lên: 09/08/2014, 06:22

... pediatric dermatology. In Pediatric Dermatology Edited by: Schachner LA, Hansen RC. Edinburgh, London, New York: Mosby; 2003:59-86. 27. Levy ML, Barron KS, Eichenfield A, Honig PJ: Naproxen -induced pseudoporphyria: ... affected by EOPA-JIA in our cohort were predominantly of Scandinavian ancestry, and so fair skin is more likely to be present in these children. In addition, they are gen...

Ngày tải lên: 09/08/2014, 10:20

... Vlachoyiannopoulos PG: European Scleroderma Study Group to define disease activity criteria for systemic sclerosis. III. Assessment of the construct validity of the preliminary activity criteria. ... preliminary SSc severity scale (Medsger severity scale), a measure of activity, damage, and severity, was used. This scale is a nine-organ disease severity scale in which for each organ system a...

Ngày tải lên: 09/08/2014, 10:23

... respectively, early from LS RA, and early or LS RA from healthy synovia. We identified several gene clusters and distinct molecular signatures specifically expressed during early or LS RA, thereby suggesting ... represented by the differences in gene-expression levels for each comparison (early versus LS RA; early RA or LS RA versus controls), we applied gene-ontology analysis using the PAN...

Ngày tải lên: 09/08/2014, 14:22