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Báo cáo y học: "Ischemic preconditioning reduces the severity of ischemia-reperfusion injury of peripheral nerve in rat" pptx

Báo cáo y học:

Báo cáo y học: "Ischemic preconditioning reduces the severity of ischemia-reperfusion injury of peripheral nerve in rat" pptx

... tis-sue and their elevation has been reported to play an essen-tial role in reducing the severity of the I/R injury byinhibiting neutrophil adhesion in postcapillary venulesand by decreasing microvascular ... similiar.However, the protective effects of acute preconditioning are protein synthesis independent, while the effects of delayed preconditioning require protein synthesis. Adap-tational responses to I/R injury ... injury to the abdominal aorta. JTrauma -Injury Inferction and Critical Care 2003, 55:795-799.9. Murry CE, Jennings RB, Reimer KA: Preconditioning withischemia: a delay of lethal cell injury...
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Báo cáo y học: " Preliminary data concerning the reliability and psychometric properties of the Greek translation of the 20-item Subjective Well-Being Under Neuroleptic Treatment Scale (SWN-20)" pdf

... in order to assess the well-being of patients receiving antipsychoticmedication independent of the improvement in their psychotic symptoms. The current studyreports on the reliability and the ... treated eitherwith FGAs or SGAs showed that both quality of life andsymptom severity improved over the study period, regard-less of the antipsychotic taken, indicating that the type of antipsychotic ... and SD participated in the gather-ing of the data, interpretation of the results and writing of the manuscript.Acknowledgements The study was based on a research grant by AstraZenca Greece.References1....
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Báo cáo y học: "DAS28 best reflects the physician''''s clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment" potx

... givea dose increase of infliximab could happen only at one timepoint. This difference in study design and therapy may explainwhy in the present study the AUC of DAS28 is smaller than in other studies ... remaining disease activity in daily prac-tice (and in clinical trials). The aim of the present analyses wasto evaluate whether the decision to increase the dose could bereflected by using single ... broadspectrum of manifestations that requires an early intensivetherapy in order to avoid joint destruction and physical disabil-ity. In order to measure the effect of therapy in daily practiceand in...
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Báo cáo y học: "Sequence similarity between the erythrocyte binding domain 1 of the Plasmodium vivax Duffy binding protein and the V3 loop of HIV-1 strain MN reveals binding residues for the Duffy Antigen Receptor for Chemokines" ppsx

... similarity between the erythrocyte binding domain 1 of the Plasmodium vivax Duffy bindingprotein and the V3 loop of HIV-1 strain MN reveals binding residues for the Duffy Antigen Receptor for Chemokines. ... consensusheparin binding site, but only a binds to DARC. To seeif the polycationic site may play a similar role in the binding proteins of other members of the DBPfamily, the same three alanine substitutions ... similarity between the erythrocytebinding domain 1 of the Plasmodium vivax Duffybinding protein and the V3 loop of HIV-1 strainMN reveals binding residues for the DuffyAntigen Receptor for ChemokinesMichael...
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Báo cáo y học: " Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice" pptx

... period.Yet, this is the first study to show the effectiveness of rapamycin in preventing pulmonary hypertensioninduced by a pathophysiologic stimulus. In our study, the extent of hypoxia-induced myocardialhypertrophy ... diameters of cardio-myocytes of the right ventricular wall while cardiomyo-cytes of the left ventricular wall were unaffected bychanges in the oxygen supply. Hypoxia-induced hypertro-phy of the ... thickening of the right ventricular wall and hypertrophy of individual cardiomyocytesFigure 6Rapamycin reverses hypoxia-induced thickening of the right ventricular wall and hypertrophy of individual...
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Báo cáo y học: "Rituximab therapy reduces activated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: depletion of memory B cells correlates with clinical response" potx

... analysis of flow cytometryexperiments. HAP participated in the design of the study anddrafted the manuscript. HK participated in the design and con-duction of the study, was involved in patient ... memory B cells in peripheral blood and bone marrow of RA patientsWe next examined the effect of rituximab therapy on memory(CD19+CD27+) B cells, the precursors of autoantibody-pro-ducing ... conduction of the study and drafted the manu-script. PS participated in the design of the study, performed the statistical analysis of the data and drafted the manuscript.GB performed the statistical...
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Báo cáo y học: "Neutrophil elastase reduces secretion of secretory leukoproteinase inhibitor (SLPI) by lung epithelial cells: role of charge of the proteinase-inhibitor complex" potx

... containing NEhas been shown to abrogate the fall in SLPI protein[27]. Ifbinding of NE to SLPI is important in the mechanism of the fall in SLPI protein, then the timing of the addition of the inhibitor ... charge of the complex between SLPI and proteinases The modelling procedure involved the use of the X-raycrystal structure of SLPI with chymotrypsin (structure filekindly provided by Professor ... concentrations of NE, rather than degradation of SLPI by NE. Since the Timing of the addition of inhibitor to NE affects concentration of SLPIFigure 6Timing of the addition of inhibitor to NE...
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Báo cáo y học: "Users' guides to the medical literature: how to use an article about mortality in a humanitarian emergency"

... keep in mind when reading amortality survey to determine the validity of the study and the applicability of the findings to theirsettings.Public health scenarioYou are a physician working ... considers whether the mortality estimatesreported in the article accurately represent the magnitude of the problem. Another way to state this question is: Do the findings of the study represent ... benchmark the severity of the crisis, by referring the study's mortality rate to internationally agreed-uponthresholds for defining states of emergency (Table 1).While several definitions...
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Báo cáo y học: "Clinical Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less"

... might in turn result in the uncertainty of the strategy for its treatment. While further delineati n g the clinicopathological and radiological features, and summarizing the surgical therapy strategy ... experience with the management of disseminated disease is very limited in the literature6, therefore, attention to the therapy strategy of this neoplasm in the future may allow a more reasonable ... 4-20). Nine patients had their tumors within the head, 2 in the body and 7 in the tail of the pancreas. Notably one patient was demonstrated to have liver metastasis. The predominant presenting...
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Báo cáo y học: " Self-reported sickness absence as a risk marker of future disability pension. Prospective findings from the DWECS/DREAM study 1990-2004"

... the generalizability of the results, and the findings may therefore not apply to the general population. The present study and the study by Gjesdal and Bratberg [10] are to our knowledge the ... analysis treating days of sickness ab-sence during 1990 as a continuous variable showed a clear trend of increase in disability pension risk with increase in absence days/yr. A 10-day increase ... 18-59. Of these, 8664 par-ticipated in the survey (response rate 90%). Of these, 5940 were employees, meaning they had been em-ployed for at least two months prior to baseline inter-view. They...
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