Báo cáo y học: "Technical phosphoproteomic and bioinformatic tools useful in cancer research" potx

... spec-trometry via SILAC and immunoaffinity purification oftyrosine phosphorylated peptides to profile candidateSRC-substrates induced by the CSF-1R tyrosine k inaseby comparing the phosphotyrosine-containing ... combined with IMAC and resulted in greater recovery and identification by MS of interest-ing phosphorylated peptides originating from yeast pher-omone signalling pathway and membrane proteinsrespectively ... unknownphosphosites from p38 and HuR protein kinases in vitro by Phosphoproteomic and Bioinformatic tools. Journal of ClinicalBioinformatics 2011, 1(1):16[http://www.jclinbioinformatics.com/content/1/1/16].2....

Báo cáo y học: "Ozone Therapy and Hyperbaric Oxygen Treatment in Lung Injury in Septic Rats"

... affected initially, and sepsis leads to severe injury in lung tissue [5]. It has been shown that pericytes in lung tissue produce proinflammatory cytokines in response to lipopolysaccharide ... activities and serum proinflammatory cytokine (TNF-α, IL-1β) le-vels were evaluated by enzyme linked immunosor-bent assay (ELISA) using commercially available kits according to the manufacturer’s instructions ... reduced oxidative stress indices and myeloperoxidase activity, levels of serum proinflammatory cytokines and histopathological injury scores considering lung tissue in septic rats. Compared...

Báo cáo y học: "Physical Exercise and Quality of Life in Breast Cancer Survivors" potx

... conducted in an Italian oncology setting. Taking together the promising findings from our study and the literature, need clearly results for inclusion of physical activity programs in comprehensive, ... preliminary evidence for the safety, feasibility, and efficacy of exercise training in breast cancer survivors. The aim of this study was to assess the association between physical exercise and ... reducing recurrence and other diseases, and extending survival in cancer survivors. Preliminary research suggests that exercise may be an effective intervention for enhancing QOL in cancer...

Báo cáo y học: "Serum, urinary, and salivary nitric oxide in rheumatoid arthritis: complexities of interpreting nitric oxide measures" doc

... is an inflammatory disease involving joints and othersystems including salivary glands. To assess NO production in RA patients, we compared levels of serum, urine, and salivarynitrite and nitrate ... NO in the pathogenesis ofjoint inflammation. Rodents in animal models of arthritis gener-Figure 3NOx/creatinine ratios in urine and serumNOx/creatinine ratios in urine and serum. Urine and ... urine constitutes 50 to 60% of the totalbody clearance of these compounds, with the remainingamounts being eliminated in unknown proportions by the exo-crine glands and by the respiratory and...

Báo cáo y học: " T cells and post menopausal osteoporosis in murine models" doc

... in elucidating thecrosstalk between the immune system and bone and in uncovering the mechanism by which sex-steroids, infection and inflammation lead to bone loss by disregulating Tlymphocyte ... approximately50% of the increase in the number of T cells in the periphery,while the remaining 50% is due to enhanced peripheralexpansion. Similarly, thymectomy decreases by approximately50% the ... cytokine remain to be determined. TheBM levels of IL-7 are significantly elevated following ovx[6,23,24], and in vivo IL-7 blockade, using neutralizing anti-bodies, is effective in preventing...

Báo cáo y học: "Thymic function and T cell parameters in a natural human experimental model of seasonal infectious diseases and nutritional burden" potx

... resulted in invasion of thethymus by day 14; accompanied by severe thymic atro-phy[17]. In humans, postmortem studies show thymic involu-tion in the severely malnourished[18]. Furthermore,cytokines ... Hebeishy NA, Rahmy AI: A post-mortem study of the thymolymphatic system in protein energymalnutrition. J Trop Med Hyg 1982, 85:109-114.19. Bodey B, Bodey B Jr, Siegel SE, Kaiser HE: Intrathymic ... likely to die frominfectious diseases as young adults[1,2]. By splitting theyear in half, seasonal fluctuations are taken into account,ensuring that periods of typical hungry/high infectionand...

Báo cáo y học: " Fat distribution and longitudinal anthropometric changes in HIV-infected men with and without clinical evidence of lipodystrophy and HIV-uninfected controls: A substudy of the Multicenter AIDS Cohort Study" potx

... of subclinical lipoatro-phy. Our findings would also suggest that abdominal adi-posity increases more quickly in HIV-infected men withclinical lipodystophy, compared to those HIV-infectedmen ... agents and 34 due todiabetes, and 35 due to inconsistent antiretroviral therapylevel in the 2 years preceding the first clinical evidence oflipodystrophy. Of the remaining 77 men, matched HIV-infected ... provided writ-ten informed consent both for the overall study and thissubstudy.Sampling methods for the Lipodystrophy SubstudyBeginning in April 1999 (visit 31), each MACS study visitincluded anthropomorphic...

Báo cáo y học: " Clinical monitoring and correlates of nephropathy in SIV-infected macaques during high-dose antiretroviral therapy" potx

... treatment and diseaseLongitudinal changes in serum chemistry were exam-ined at different stages of disease and treatment and revealed an initial increase in BUN and creatinine and decrease in phosphorus, ... features of ART nephropathy. Ectasia of renal tubules containing eosinophilic proteinaceous material (tubularproteinosis) (A) and focal lymphocytic infiltrate (B). Mild cytomegaly and anisonucleosis ... within 3 years of treatment. In contrast to PMPA,limited information on systemic toxicity in rhesus monkeys is available for FTC (5-fluoro-1-(2R,5S)-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine;...

Báo cáo y học: "Slow conduction and gap junction remodeling in murine ventricle after chronic alcohol ingestion" potx

... study. RC participated in theelectron microscopy. YM participated in the protein analysis (western blot and immunostaining). YS carried out the interpretation of the findings. CIparticipated in ... alcoholingestion. Cellularity (A and B, stained with hematoxyllin) and capillary network (C and D, stained for CD31) in the left ventricular myocardium.A and C, are from the control group and B and ... frequently seen in the vicinity of the adhe-rens junctions for both groups (Figure 4E and 4F).Optical mappingDuring optical mapping examination ventricular tachyar-rhythmia, including ventricular...

Báo cáo y học: "Cardiac CT and MRI guide surgery in impending left ventricular rupture after acute myocardial infarction'''' ppt

... resonance imaging. Intraoperative palpation of the left lateral wall was guided by thecardiac MRI and CT findings and confirmed the presence of focally thinned and weakenedmyocardium, covered by epicardial ... and any accompanyingimages. A copy of the written consent is available forreview by the Editor -in- Chief of this journal.Competing interestsThe authors declare that they have no competing interests.J.V.C. ... aneurysmorrhaphy was subsequently performed in addition to coronary bypass surgery and a mitral valve repair. The patient was discharged home onpost operative day eight in good condition and...

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