Báo cáo y học: "Discovering and validating unknown phosphosi

Báo cáo y học: "Discovering and validating unknown phosphosites from p38 and HuR protein kinases in vitro by Phosphoproteomic and Bioinformatic tools" doc

... Access Discovering and validating unknown phosphosites from p38 and HuR protein kinases in vitro by Phosphoproteomic and Bioinformatic tools Elena López 1,5* , Isabel López 2 , Julia Sequí 3 and Antonio ... spectrometry (MS). P38 and HuR protein kinases have been reported extensively in the general principles of signalling pathways modulated by...

Ngày tải lên : 10/08/2014, 09:22

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Báo cáo Y học: Selection of effective antisense oligodeoxynucleotides with a green ﬂuorescent protein-based assay Discovery of selective and potent inhibitors of glutathione S-transferase Mu expression doc

... secondary antibody. EGFP- containing proteins were visualized with enhanced chemiluminescence. The positions and molecular weights of the marker proteins are indi- cated in the left margin. In the ... [31,32]. The inhibition of EGFP–GSTM fusion protein expression was reﬂected by a decrease in GST enzyme activity, as determined in a CDNB conjugation assay. AS-6 displayed potent...

Ngày tải lên : 31/03/2014, 15:20

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Báo cáo y học: "Validation of a specific measure to assess healthrelated quality of life in patients with schizophrenia and bipolar disorder: the ‘Tolerability and quality of life’ (TOOL) questionnaire" doc

... established by the Structur ed Clinical Interview for DSM-IV, being clinically stable (defined as having had no changes in severity or new treatments initiated in the last month), and taking a single ... were evaluated in an exploratory analysis of the answers given to the TOOL distribution and by using percentiles 25, 50 and 7 5 (Tukey’s Hinges). Validity Regarding construct...

Ngày tải lên : 09/08/2014, 01:21

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Báo cáo y học: "Polarized subsets of human T-helper cells induce distinct patterns of chemokine production by normal and systemic sclerosis dermal fibroblasts" doc

... mRNA induced by Th1 cells was not significantly affected by any of the inhibitors used, but the MCP-1 levels induced by Th2 cells were affected strongly by both U-0126 and PSI and weakly by the ... JM: The inhibitory activity of human interleukin-1 receptor antagonist is enhanced by type II interleukin-1 soluble receptor and hin- dered by type I interleukin-1 soluble recep...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: " Comparison of exhaled breath condensate pH using two commercially available devices in healthy controls, asthma and COPD patients" pptx

... we observed in the present study [10]. This may be explained by the difference in the duration of degasification, which was 10 minutes in the study by Soyer, and 20 minutes in the present study. The ... patients may be explained by increased pulmonary inflammation in unstable asthmatics. COPD subjects with GOLD grade 2 were investigated in the repeatability study from Bo...

Ngày tải lên : 12/08/2014, 14:20

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Báo cáo y học: "Human immunodeficiency virus integrase inhibitors efficiently suppress feline immunodeficiency virus replication in vitro and provide a rationale to redesign antiretroviral treatment for feline AIDS" pdf

... supported by phylogenetic analysis. In line with these bioinformatic analyses, FIV replication was efficiently inhibited in acutely infected cell cultures by three investigational INSTIs, designed ... chronically infected feline T-lymphocyte FL-4 cells [46], as previously described [47]. In the uninfected controls, drug cytotoxicity and CC 50 val- ues were determined by trypa...

Ngày tải lên : 13/08/2014, 05:22

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$Báo cáo y học: "Comparative study on saponin fractions from Panax notoginseng inhibiting inflammation-induced endothelial adhesion molecule expression and monocyte adhesion" docx$

Báo cáo y học: "Comparative study on saponin fractions from Panax notoginseng inhibiting inflammation-induced endothelial adhesion molecule expression and monocyte adhesion" docx

... (manuscript in preparation). Interestingly, PDS showed a stronger inhibitory effect than the PTS and PNS fractions on HCD-induced ICAM-1 and VCAM-1 mRNA levels in the rat aorta. Our in vitro and in ... VCAM-1 and ICAM-1 at both the mRNA and protein levels. CAMs is a protein family including VCAM-1, ICAM-1, E-selectin, P-selectin, PECAM-1 and mucosal addressin CAM-...

Ngày tải lên : 13/08/2014, 14:20

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$Báo cáo hóa học: " Nano-regime Length Scales Extracted from the First Sharp Diffraction Peak in Non-crystalline SiO2 and " docx$

Báo cáo hóa học: " Nano-regime Length Scales Extracted from the First Sharp Diffraction Peak in Non-crystalline SiO2 and " docx

... Si and Si/Ge devices heralding a transition into nano-scale circuits and systems on a Si chip. Keywords Non-crystalline materials Á Nano-crystalline thin films Á Nano-crystalline/non-crystalline ... of non-crystalline and nano-crystalline thin films. It has been first demonstrated in the Bell and Dean model [15, 16], and later by computer generated modeling [17–19], and molecul...

Ngày tải lên : 22/06/2014, 00:20

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Báo cáo khoa học: "The response of dehydrated Douglas fir (Pseudotsuga menziesii) pollen to three in vitro viability assays and their relationship to actual fertility" doc

... lot varied and ranged from 1-5 yr. In vitro viability assays Germination Media type The procedure for germinating Douglas fir pollen initially followed the technique described by Ho and ... determined by X-ray analyses as described below. In vivo fertility All pollen lots tested for in vitro viability were also tested for in vivo fertil...

Ngày tải lên : 08/08/2014, 23:22

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Báo cáo y học: "Assessment of immune response to repeat stimulation with BCG vaccine using in vitro PBMC model" pdf

... benzidine in hydrogen peroxide (TMB/H2O2) was added and incubated for 10 min. The reaction was stopped by adding 2.5N sulphuric acid and the optical density of plates was read at 450 nm. Interferon ... ammonia/min from adenosine in standard assay conditions. Results were expressed as units per litre per minute (U/L/min). The assays were performed in triplicate and blind to the...

Ngày tải lên : 11/08/2014, 08:21

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