Báo cáo y học: "Moving towards high density clinical signature studies with a human proteome catalogue developing multiplexing mass spectrometry assay panels" doc

... only one epitope on CD69. Interestingly, the amino acid sequence of this main epitope (EKNLYWI) is highly homologous to a part (EKRLYWI) of low-density-lipoprotein-receptor-related protein 2 (LRP2). In ... (0) 2 (50) 0 (0) 2 (50) 0 (0) 2 (50) LRP2 = low-density-lipoprotein-receptor-related protein 2; OA = osteoarthritis; RA = rheumatoid arthritis; SLE = systemic lupu...

Ngày tải lên: 09/08/2014, 01:21

... arthritis over time: influence of new therapies and changes in management approach: analysis of the EMECAR cohort Isidoro González-Alvaro 1 , Miguel Angel Descalzo 2 , Loreto Carmona 2 for the EMECAR ... leading to enhancement of patients' treatment. Competing interests The EMECAR study was funded by the Spanish Society of Rheumatology, the...

Ngày tải lên: 09/08/2014, 13:22

... respectively. Interestingly, there is no overlap in candidate regions identified in the two populations. When the authors restrict their analysis to candidate genes and pathways involved in high- altitude ... EPAS1, on the other hand, was only identified in the Tibetan populations, and PPARA was not considered with the HIF pathway genes in the Andean analysis, so it remains...

Ngày tải lên: 09/08/2014, 20:22

... article as: Rezeli et al.: Moving towards high density clinical signature studies with a human proteome catalogue developing multiplexing mass spectrometry assay panels. Journal of Clinical Bioinformatics ... Open Access Moving towards high density clinical signature studies with a human proteome catalogue developing multiplexing ma...

Ngày tải lên: 10/08/2014, 09:22

... results indicate that active local implementation of clinical guidelines involving clinicians can change behaviour and maintain compliance. Background Transferring research results into routine clinical ... collaboration for organiza- tional learning of best practice and change of clinical practice. The teams were encouraged to involve all staff at the clinic in adapting t...

Ngày tải lên: 11/08/2014, 05:21

... murine VCAM-1 and iNOS promoters are activated by AP-1, NFkB, and by STAT1 and its secondary target, inter- feron regulatory factor-1 [12-14,44]. TNFα is a strong acti- vator of AP-1 and NFkB, and ... for citation purposes) Journal of Inflammation Open Access Research Sensitivity of mice to lipopolysaccharide is increased by a high saturated fat an...

Ngày tải lên: 11/08/2014, 08:21

... health monitoring of patients with schizophrenia. Am J Psychiatry 2004, 161(8):1334-1349. 14. American Diabetes Association, American Psychiatric Association, American Association of Clinical ... primarily due to cardiovas- cular disease [8]. Second-generation antipsychotics (SGA) or atypical drugs have gained widespread acceptance for the management of patients with schiz...

Ngày tải lên: 11/08/2014, 17:20

... Central Page 1 of 3 (page number not for citation purposes) Journal of Medical Case Reports Open Access Case report Unusual presentation of Lisfranc fracture dislocation associated with high-velocity ... joint associated with sledding. Case presentation: A 19-year-old male college student presented to the emergency department with a Lisfranc frac...

Ngày tải lên: 11/08/2014, 21:22

... hip. Bone biomarkers suggest increased bone turnover. Keywords: bone biomarkers, bone mineral density, chronic obstructive pulmonary disease, osteoporosis Background Chronic obstructive pulmonary ... disease factors such a s the persisting chronic systemic inflam- matory state. We explored this hypothesis by determin- ing BMD and circulating bone biomarkers in me...

Ngày tải lên: 12/08/2014, 13:22

... with mAb 6A2 B2 on human placenta (A) and an acute MS lesion (B). Arrowheads in A point to syncytiotrophoblast cell layer. Strong staining with 6A2 B2 was seen in a case of fulminant MS in activated ... propose to designate ERVWE2, has retained coding capacity and can produce ex vivo an N-terminally truncated Env protein, named N-Trenv. Detection of an antig en by 6A2 B2 in placen...

Ngày tải lên: 13/08/2014, 01:20

... involved in the study. JPM partici- pated in the study design and coordination. BB supervised the study, and participated in its design and coordination. All authors read and approved the final manuscript. Acknowledgments We ... approxi- mately 4 days compared to the wt virus. Replication of the Q591L mutant was significantly better, with a delay of only one day co...

Ngày tải lên: 13/08/2014, 13:20

... Domburgh et al.: Correlates of self-reported offending in children with a first police contact from distinct socio- demographic and ethnic groups. Child and Adolescent Psychiatry and Mental Health 2011 ... migration stress, but also from the migration stress of their parents as stress may lead to inadequate parenting, and from the family van Domburgh et...

Ngày tải lên: 13/08/2014, 18:22

... purposes) Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine Open Access Case report Blunt traumatic pericardial rupture and cardiac herniation with a penetrating twist: two case reports Peter ... Galloway - drrobgalloway@gmail.com; Marie Healy - marie.healy@bartsandthelondon.nhs.uk * Corresponding author Abstract Background: Blunt Traumatic...

Ngày tải lên: 13/08/2014, 23:21

... between weight loss and engagement with a web-based food and exercise diary in a commercial weight loss programme: a retrospective analysis. International Journal of Behavioral Nutrition and Physical ... and engagement with a web-based food and exercise diary in a commercial weight loss programme: a retrospective anal...

Ngày tải lên: 14/08/2014, 08:20

... we determined that the vast majority of amino acid substitutions could be explained by single non-synonymous nucleotide changes. Inspection of the types of amino acid substitutions in repeats ... deeper insight into the substitution patterns in repeats and adjacent regions can be obtained by the analysis of the types of amino acid substitutions, as we...

Ngày tải lên: 14/08/2014, 16:21