Báo cáo y học: " Phase 1 cardiovascular rehabilitation: be aggressive" pot

 Báo cáo y học: "PARP-1 inhibitors: are they the long-sought genetically specific drugs for BRCA1/2-associated breast cancers"

Báo cáo y học: "PARP-1 inhibitors: are they the long-sought genetically specific drugs for BRCA1/2-associated breast cancers"

... sensitivity to AG143 61, a very potent PARP -1 inhibitor (K I =5nM), and NU1025, a moderately potent PARP -1 inhibitor (K I =50nM). NU1025 treatment also profoundly reduced colony formation (up to 10 0 ... inhibitors: AG143 61, NU1025, and 3- aminobenzamide (3AB) [36]. We first tested a BRCA1 mutant ES cell line [BRCA1 trEx 11/ Δ 11 that carries one BRCA1 mutant allele truncated...
Ngày tải lên : 31/10/2012, 16:57
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Báo cáo Y học: ik3-1/Cables is a substrate for cyclin-dependent kinase 3 (cdk 3) pdf

Báo cáo Y học: ik3-1/Cables is a substrate for cyclin-dependent kinase 3 (cdk 3) pdf

... Enzymol. 2 01, 11 0 14 9. 16 . Wang, Y. & Prives, C. (19 95) Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases. Nature 376, 88– 91. 17 . Zhao, J., Dynlacht, ... Projects. REFERENCES 1. Sherr, C.J. (19 93) Mammalian G1 cyclins. Cell 73, 10 59 10 65. 2. Resnitzky, D. & Reed, S.I. (19 95) Different roles for cyclins D1 and q FEBS 20 01...
Ngày tải lên : 24/03/2014, 04:21
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Báo cáo Y học: Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) docx

Báo cáo Y học: Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) docx

... end A15 ) 81. 1 )23.4 T8 )48.5 )1. 3 G9 2.5 )19 .6 Formamide end A5 )19 .6 )18 .8 T18 )12 .5 )1. 3 C4 10 .9 )5.4 G19 0.0 )14 .6 Ó FEBS 2002 Two 1 : 1 binding modes for distamycin (Eur. J. Biochem. 269) 2873 that ... the refined crystal geometry the drug is rather too tightly packed against the G19 base. The interaction can be improved by locally relaxing the drug geometry, but no hydrog...
Ngày tải lên : 24/03/2014, 04:21
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Báo cáo y học: "HIV-1 Capsid Assembly Inhibitor (CAI) Peptide: Structural Preferences and Delivery into Human Embryonic Lung Cells and Lymphocyte" pptx

Báo cáo y học: "HIV-1 Capsid Assembly Inhibitor (CAI) Peptide: Structural Preferences and Delivery into Human Embryonic Lung Cells and Lymphocyte" pptx

... life cycle. Virology. 19 98; 2 51: 1- 15. 7. Bryant M, Ratner L. Myristoylation-dependent replication and assembly of human immunodeficiency virus 1. Proc Natl Acad Sci U S A. 19 90; 87: 523-7. ... Solid Phase Peptide Synthesis. I The Synthesis of a Tetrapeptide. J Americ Chem Soc. 19 63; 85: 214 9-54. 27. Paquet A. Introduction of 9-fluorenylmethoxycarbonyl, tri- chloroethoxycar...
Ngày tải lên : 08/08/2014, 17:20
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Báo cáo y học: "IGF-1 regulates cAMP levels in astrocytes through a β2-adrenergic receptor-dependant mechanism" pot

Báo cáo y học: "IGF-1 regulates cAMP levels in astrocytes through a β2-adrenergic receptor-dependant mechanism" pot

... by inhibiting Raf -1 kinase activity, an effect that has been attributed to phosphorylation of Raf -1 by protein kinase A [17 -19 ]. Interestingly, we have shown that cultured β 2 AR KO astrocytes, ... levels in KO astrocytes, as compared to WT cells. Treatment with NE for 15 minutes in- creased cAMP levels in both WT and KO astrocytes by 11 5 .1% and 13 5.3%, respectively. NE-induc...
Ngày tải lên : 08/08/2014, 17:20
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Báo cáo y học: "Fluvoxamine monotherapy for psychotic depression: the potential role of sigma-1 receptors" pps

Báo cáo y học: "Fluvoxamine monotherapy for psychotic depression: the potential role of sigma-1 receptors" pps

... 2009, 8:26 doi :10 .11 86 /17 44-859X-8-26 Received: 10 November 2009 Accepted: 21 December 2009 This article is available from: http://www.annals-general-psychiatry.com/content/8 /1/ 26 © 2009 Furuse ... antipsychotic drugs. Background Psychotic depression is a clinical subtype of major depres- sive disorder and is characterized by psychosis accompa- nied by relatively severe depressive sy...
Ngày tải lên : 08/08/2014, 23:21
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Báo cáo y học: " Sigma-1 receptor agonist fluvoxamine for delirium in patients with Alzheimer’s disease pot

Báo cáo y học: " Sigma-1 receptor agonist fluvoxamine for delirium in patients with Alzheimer’s disease pot

... haloperidol, and benztropine. Am J Psychiatry 19 96, 15 3:965-966. 13 . Armstrong SC, Schweitzer SM: Delirium associated with paroxetine and benztropine combination. Am J Psychiatry 19 97, 15 4:5 81- 582. 14 . Hashimoto ... 55:492-495. 11 . Amir I, Dano M, Joffe A: Recurrent toxic delirium in a patient treated with SSRIs: is old age a risk factor?. Isr J Psychiatry Relat Sci 19 97, 34...
Ngày tải lên : 08/08/2014, 23:21
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Báo cáo y học: "Sigma-1 receptor agonist fluvoxamine for delirium in intensive care units: report of five cases" doc

Báo cáo y học: "Sigma-1 receptor agonist fluvoxamine for delirium in intensive care units: report of five cases" doc

... research. J Geriatr Psychiatry Neurol 19 98, 11 :15 9 -16 1. 21. Burke WJ, Roccaforte WH, Wengel SP: Treating visual hallucinations with donepezil. Am J Psychiatry 19 99, 15 6 :11 17 -11 18. 22. Wengel SP, ... 20/32 10 /32 (1 day) 3 M 76 Sepsis by pyelonephritis 50 -15 0 mg 21/ 32 10 /32 (3 days) 4M85Cerebral infarction 50 mg 19 /32 10 /32 (1 day) 5M86Pulmonary emphysema, sev...
Ngày tải lên : 08/08/2014, 23:21
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Báo cáo y học: "Sigma-1 receptor agonist fluvoxamine for postoperative delirium in older adults: report of three cases" docx

Báo cáo y học: "Sigma-1 receptor agonist fluvoxamine for postoperative delirium in older adults: report of three cases" docx

... General Psychiatry 2 010 , 9:28 Received: 14 May 2 010 Accepted: 24 June 2 010 Published: 24 June 2 010 This article is available from: http://www.annals-general-psychiatry.com/content/9 /1/ 28© 2 010 Furuse ... report of five cases. Ann Gen Psychiatry 2 010 , 9 :18 . 15 . Trzepacz PT, Baker RW, Greenhouse J: A symptom rating scale for delirium. Psychiatry Res 19 88, 23:89-97. 16 . Co...
Ngày tải lên : 08/08/2014, 23:21
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