Báo cáo y học: "Rapamycin-loaded nanoparticles for inhibition of neointimal hyperplasia in experimental vein grafts" pps

... SapienzaÕ, Roma, Italy Ligand binding by the aryl hydrocarbon receptor (AhR), a member of the bHLH-PAS family of transcriptional reg- ulatory proteins, has been mapped to a region within the second ... ail: Anna.Tramontano@uniroma1.it Abbreviations: AhR, aryl hydrocarbon receptor; PYP, photoactive yellow protein; LBD, ligand binding domai n; mAhR, mouse aryl hydr...

Ngày tải lên: 24/03/2014, 00:21

... efficacy produced by CP-690550 in the rodent models of arthritis may result from its ability to affect signaling of a number of cytokines including IL-2, -7, -15 and -21 as a con- sequence of JAK3 inhibition ... is properly cited. Abstract Introduction CP-690550 is a small molecule inhibitor of Janus kinase 3 (JAK3), a critical enzyme in the signaling pathway of...

Ngày tải lên: 09/08/2014, 10:22

... the treatment of gout: 5-yr find- ings of the FOCUS efficacy and safety study. Rheumatology 2009, 48:188-194. 50. Hu M, Tomlinson B. Febuxostat in the management of hyper- uricemia and chronic gout: ... glucocortico- steroid treatment of acute gout is also particularly significant, for example, for subjects with CKD. Specifically, prednisolone 35 mg daily for 5 days...

Ngày tải lên: 09/08/2014, 14:21

... Therapy Open Access Research Vitamin supplementation for prevention of mother-to-child transmission of HIV and pre-term delivery: a systematic review of randomized trial including more than 2800 ... transmission (MTCT) of HIV and increased preterm delivery. We aimed to determine the efficacy of vitamins on the prevention of MTCT and pr...

Ngày tải lên: 10/08/2014, 05:20

... 3c). Assay of cytokines in blood culture supernatants from healthy and HIV- positive subjects Cytokines were measured in blood culture supernatants from healthy and HIV- infected subjects. Interestingly, ... synthesis in response to H37Rv infection and NAC treatment was similar in healthy subjects and HIV patients. H37Rv induced almost ten-fold increases in IL-...

Ngày tải lên: 10/08/2014, 05:20

... 0.35). Rapamycin Pharmacokinetics Measurement of rapamycin levels in vein grafts demon- strated the presence of drug in vein grafts at 0 days (after the vein being immersed in rapamycin-loaded ... gets hydrolyzed, resulting in an intracellular drug delivery and thereby significantly inhi- biting VSMCs p roliferation. An important finding was, long-term release of rapamycin...

Ngày tải lên: 10/08/2014, 09:21

... Yazigi A, Haddad F, Hayeck G, Rassi IE, Ashoush R, Jebara V: Postoperative oral amiodarone versus oral bisoprolol as prophylaxis against atrial fibrillation after coronary artery bypass graft surgery: ... tachyarrhythmias after coronary artery bypass graft surgery. J Cardiothorac Vasc Anesth 2001, 15:204-9. 83. Shiga T, Wajima Z, Inoue T, Ogawa R: Magnesium prophylaxis for arrhyt...

Ngày tải lên: 10/08/2014, 09:23

... 5:256 http://www.jmedicalcasereports.com/content/5/1/256 Page 2 of 4 CAS E REP O R T Open Access Parenteral lidocaine for treatment of intractable renal colic: a case series Hassan Soleimanpour 1* , Kamaleddin Hassanzadeh 2 , ... Hassanzadeh 2 , Dawood Agha Mohammadi 3 , Hassan Vaezi 1 and Robab Mehdizadeh Esfanjani 4 Abstract Introduction: We report a case series...

Ngày tải lên: 10/08/2014, 23:21

... effect of increasing PL molecular weight was an increase in size, an increase in zeta-potential and a decrease of % of cell viability (Table 2). Table 1 summa- rized the different properties of assemblies ... mg/mL and 0.01–10.00 mg/mL, respectively. Firstly, DODAB BF and drug were allowed to interact for 10 minutes. Thereafter, CMC was added and allowed to interact for...

Ngày tải lên: 11/08/2014, 00:22

... Respiratory Dis- ease in Canada the Canadian Institute for Health Information, Cana- dian Lung Association, Health Canada, Statistics Canada. Ottawa: Health Canada; 2001:65-87. 7. Langley JM, Wang ... studies; train and mentor students, fel- lows, and new researchers in order to increase clinician and researcher capacity; and develop and advance a research agenda for meth...

Ngày tải lên: 11/08/2014, 05:21

... is involved in the life-cycle of HIV-1- based vectors. Our finding also supports the hypothesis that cellular DSB repai r proteins are invo lved in PIR. At the same time, these proteins clearly ... required for efficient integration or PIR. On the other hand, some reduce the efficiency of integration. Finally, some are involved in integration site selection. We have st...

Ngày tải lên: 12/08/2014, 01:21

... were performed with mAbs specific for the HCV core. Viral proteins levels were decreased after 24 hr of the transfection of 100 nM of siRNA specific for HCV, and this dec rease con tin ued for seven ... for Day 3 by Z3 andDay7byZ5.ReductionofcoreproteinexpressionwasreportedatDay2postZ 3siRNA transfection and at Day 1 post Z5 siRNA, which was persistent for Day 4 for t...

Ngày tải lên: 12/08/2014, 04:21

... al.: Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control study. Respiratory Research 2011 12:37. Miniati et al. ... lacking transmembrane and cytosolic domains, acts as a decoy receptor for R AGE ligands in the extracellular compart- ment, and is believed to afford p...

Ngày tải lên: 12/08/2014, 13:22

... Page 2 of 2 (page number not for citation purposes) Critical Care Vol 13 No 1 Gunther and English models of higher level cognition and behavior are being developed. The hope is that these may help ... these may help bridge the gap between bench research and bedside care. Experimental investigations that incorporate the ability to assess subtle changes in animal cognition offer...

Ngày tải lên: 13/08/2014, 11:23

... with aneurysmal subarachnoid haemorrhage (SAH) and bacterial meningitisBlood glucose in patients with aneurysmal subarachnoid haemor- rhage (SAH) and bacterial meningitis. Individual courses of ... was performed for 7 to 10 days after SAH, and daily medi- ans of the microdialysate concentrations were calculated for each patient. Diagnosis of bacterial meningitis a...

Ngày tải lên: 13/08/2014, 11:23