Báo cáo y học: "The faunal drugstore: Animal-based remedies used in traditional medicines in Latin America" pptx
... as: Alves and Alves: The faunal drugstore: Animal-based remedies used in traditional medicines in Latin America. Journal of Ethnobiology and Ethnomedicine 2011 7:9. Submit your next manuscript to ... Access The faunal drugstore: Animal-based remedies used in traditional medicines in Latin America Rômulo RN Alves 1* , Humberto N Alves 2 Abstract Zoothera...
Ngày tải lên: 10/08/2014, 09:21
... be involved in the interaction. In this way, it seems likely that proteins such as Eos may be able to bind to CtBP that is already associated with another PXDLS motif-containing protein. For instance, ... through targeting of a C-terminal binding protein-histone deacetylase complex. FEBS Letts. 429, 183–188. 31. Wen, Y. , Nguyen, D., Li, Y. & Lai, Z.C. (2000) The N-terminal BTB/POZ...
Ngày tải lên: 21/02/2014, 01:21
... these findings suggest that children orphaned by AIDS may have unmet psychological needs. The finding of strikingly high PTSD-type symptoms in this study indicate that this should be a key area ... experiencing psychological dif- ficulties, including depression, anxiety and irritability (34%), fugue, offending and hyperactivity (27%), and PTSD (39%). Studies in the USA In New York, orph...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis" ppt
... examines the evidence for hypoxia in inflammatory and destructive joint disease, and discusses the interplay between alterations in oxygen tension, vascularity and inflammatory signalling pathways. ... notably contain ankyrin repeat motifs containing the asparagine residue hydroxylated by FIH [31]. Another target, identified only recently as an FIH substrate and also possessing an ankyrin...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "The PI3K–NF-κB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis" pdf
... functionality and is accompanied by modulation of downstream cell growth regulatory proteins resulting in tumor growth inhibition. In the present study, key signaling proteins in the synovial cells and ... adjuvant-induced arthritis; BSA = bovine serum albumin; DLN = drain lymph node; GSK-3β = glycogen syn- thase kinase-3β; H & E = hematoxylin and eosin; IB-MECA = 1-deoxy-1-(6-{[(3-...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis" pps
... player in promoting the production of inflammatory and degradative mediators in the OA synovium. In particular, our results indicate a role for both TNF-α and IL-1β in driving inflammatory responses ... cartilage. In this study, we investigate the role of synovial macrophages and their main proinflammatory cytokines, interleukin (IL)-1 and tumour necrosis factor-alpha (TNF-α), in...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "The identification and characterization of a novel protein, c19orf10, in the synovium" docx
... aggregates stained positively (arrow). (e) Intense staining of individual cells in the lining layer of a typical OA synovium. (f) An area of an OA synovium demonstrates a lining layer completely devoid ... devoid of c19orf10 staining. (g) Intense staining of a hyperplastic RA synovial lin- ing cell layer. This staining was typical of most areas of RA synovium where the lining was hyperp...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "The impact of infliximab treatment on quality of life in patients with inflammatory rheumatic diseases" ppsx
... 4 Clinically meaningful improvement in health-related quality of lifeClinically meaningful improvement in health-related quality of life. Percentage of patients who achieved a clinically meaningful ... pre- viously. In each study, patients were randomly assigned to receive either infliximab or placebo in a 3-dose induction regi- men followed by maintenance therapy. Patients in ATTR...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: "The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis" pps
... examines the evidence for hypoxia in inflammatory and destructive joint disease, and discusses the interplay between alterations in oxygen tension, vascularity and inflammatory signalling pathways. ... notably contain ankyrin repeat motifs containing the asparagine residue hydroxylated by FIH [31]. Another target, identified only recently as an FIH substrate and also possessing an ankyrin...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: "The ITGAV rs3738919 variant and susceptibility to rheumatoid arthritis in four Caucasian sample sets" pptx
... Criswell LA, Seldin MF, Kastner DL, Amos CI, Sninsky JJ, Gregersen PK: A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) The following Additional ... established, with many other loci also incriminated. These include the protein tyrosine phos- phatase non-receptor 22 (PTPN22) gene [4,5], cytotoxic T- lymphocyte antigen 4 (CTLA4) [6], an int...
Ngày tải lên: 09/08/2014, 14:22