Báo cáo y học: "If you don''''''''t believe it, it won''''''''t help you": use of bush medicine in treating cancer among Aboriginal people in Western Australia" pps
Báo cáo y học: "If you don''''t believe it, it won''''t help you": use of bush medicine in treating cancer among Aboriginal people in Western Australia" pps
... original work is properly cited. Research "If you don't believe it, it won't help you& quot;: use of bush medicine in treating cancer among Aboriginal people in Western Australia Shaouli ... " Secrecy and mystery abound in the Aboriginal commu- nity about the use and availability of bush medicine. This inevitably means poor av...
Ngày tải lên: 10/08/2014, 09:21
Báo cáo y học: "Peripheral blood but not synovial fluid natural killer T cells are biased towards a Th1-like phenotype in rheumatoid arthritis" pptx
... T-helper (Th)1-type and Th2-type cytokines, and CD4 - CD8 - (double negative) NKT cells that primarily produce Th1- type cytokines. The ability to secrete cytokines and chemok- ines rapidly ... These findings indicate that the reactivity of peripheral blood NKT cells to α-GalCer is impaired in some RA patients, whereas it is intact and even increased in others. Cytokine profile of...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "CD134 as target for specific drug delivery to T cells in adjuvant arthritis" pps
... Liposomes used for investigating in vitro binding and internalization contained 0.1 mol% Texas red-phosphatidylethanolamine (Molecular Probes Europe). Liposomes used for studying drug delivery in vitro ... in a semi- blinded set-up. Severity of arthritis was scored by grading each paw from 0 to 4 based on erythema, swelling and immo- bility of the joints, resulting in a maximum sc...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "No evidence for an association between the -871 T/C promoter polymorphism in the B-cell-activating factor gene and primary Sjögren''''s syndrome" pptx
... pSS. Interestingly, a longitudinal study evaluating BAFF levels also reported that the BAFF mRNA phenotype did not match the BAFF protein phenotype in as many as 42% of patients with SLE, with ... Boyle DL, Kalled SL, Carson DA, Kipps TJ: Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in response to proinflammatory cy...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "TPO, but not soluble-IL-6 receptor, levels increase after anagrelide treatment of thrombocythemia in chronic myeloproliferative disorders"
... thrombopoi- etin-induced myelofibrosis in mice. Blood 2002;100:3495-503 32. Erusalimsky JD, Franklin R and Hong Y. Is the platelet lowering activity of anagrelide mediated by its major metabolite 2-amino-5,6-dichloro-3,4-dihydroquinazoline ... R, Takayama T, Kato J, Yamauchi N, Ko- gawa K, Sakamaki S, Hirayama Y, Kohda K, Niitsu Y. Involve- ment of transforming growth factor-beta...
Ngày tải lên: 03/11/2012, 10:52
Báo cáo Y học: Matrilysin (matrix metalloprotease-7) cleaves membrane-bound annexin II and enhances binding of tissue-type plasminogen activator to cancer cell surfaces docx
... inhibited by an MMP inhibitor, N-(R)-[2-(hydrox- yaminocarbonyl)-methyl]-4-methylpentanoyl-l-naphthyl- alanyl-l-alanine-2-aminoethyl amide (TAPI-1), but not by a mixture of inhibitors for serine, aspartic ... possibly by binding to intact annexin II, and interact with tPA via its C-terminal lysine. It is supposed that the cleavage of cell surface annex- in II by matrilysin contributes...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo Y học: Extra terminal residues have a profound effect on the folding and solubility of a Plasmodium falciparum sexual stage-specific protein over-expressed in Escherichia coli pptx
... indicative of either proper folding or of increased solubility of the protein of interest. We propose that the success of fusion protein systems should be ascertained only once the protein of interest ... soluble in five of the constructs resulting in very poor yields. Intriguingly, in the sixth con- struct, the yield of soluble fusion protein with an extended carboxyl te...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo Y học: Cytochrome c from a thermophilic bacterium has provided insights into the mechanisms of protein maturation, folding, and stability potx
... understand protein stability, it is necessary to carry out precise comparative studies using homologues exhibiting high sequence identity with similar 3D structures, but differing in stability. From ... protein stability, we attempted to achieve maximal enhancement of the stability of PA c-551 by introducing minimal mutations into spa- tially separate regions. Five amino-acid residues...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo Y học: Hemocyanin from the keyhole limpet Megathura crenulata (KLH) carries a novel type of N-glycans with Gal(b1–6)Man-motifs doc
... overview of the complexity of KLH glycosylation, intact glycoprotein was subjected to automa- ted hydrazinolysis. Resulting glycans were pyridylaminated and analyzed by on-line ESI-MS. Both monitoring ... Chemical Industries, Ltd, Osaka, Japan; 2 Institute of Biochemistry, University of Giessen, Giessen; and 3 Institute of Zoology, Johannes-Gutenberg University of Mainz, Mainz, Ge...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo Y học: Arginine 121 is a crucial residue for the specific cytotoxic activity of the ribotoxin a-sarcin potx
... results obtained, it can be concluded that Arg121 of a-sarcin, a conserved residue in its fungal ribo- toxins family, plays a crucial role in the cytoxicity shown by this protein. Firstly, because this ... obtained (density or quantity of a spot calculated from its volume made of the sum of all pixel intensities composing the spot obtained with a photo documentation system UVI-T...
Ngày tải lên: 31/03/2014, 23:20