... prepared using BOBSCRIPT [34]. Ó FEBS 2002 Two 1 : 1 binding modes for distamycin (Eur. J. Biochem. 269) 2875 Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) Koen Uytterhoeven 1 , ... current crystal structures describe the interaction of distamycin in the minor groove of the central CAATTG sequen...
Ngày tải lên: 24/03/2014, 04:21
... Family history of polycythemia in a subject with polycythemia should raise the suspicion for the presence of a high affinity Hb variant [14]. A low P50 value (obtained from venous gas parameters) ... and in turn, can change the affinity of Hb for oxygen. The majority of mutations affecting oxygen affinity result in high affinity Hb variants which result...
Ngày tải lên: 08/08/2014, 16:23
Báo cáo y học: "Fat-Storing Multilocular Cells Expressing CCR5 Increase in the Thymus with Advancing Age: Potential Role for CCR5 Ligands on the Differentiation and Migration of Preadipocytes" pot
... the thymus with age. Hy- pothesizing that the increased expression of chemokines and the CCR5 receptor may play a role in adipocyte recruitment and/ or differentiation within the aging thymus, ... is enhanced in the aging thymus. To further investigate a possible role for CCR5 on immigration of fat-storing cells, we ex- amined the expression of...
Ngày tải lên: 08/08/2014, 18:20
Báo cáo y học: "Hereditary angioedema: beyond international consensus - circa December 2010 - The Canadian Society of Allergy and Clinical Immunology Dr. David McCourtie Lecture" pps
... 45:11 2-2 1. doi:10.1186/171 0-1 49 2-7 -1 Cite this article as: Bowen: Hereditary angioedema: beyond international consensus - circa December 2010 - The Canadian Society of Allergy and Clinical Immunology Dr. David McCourtie ... meeting: http://www.hemophilia.ca/en/about- the- chs/collabora- tion/network -of- rare-blood-disorder- organizat...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanisms of action" pps
... administration of HA have been shown in both electrophysiology and animal Review Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanisms of action Larry W ... is stimulated by IL-1, and increases the release of PGs from cartilage [37]. Table 1 Definition and characteristics of hyaluronan (hyaluronic...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "A monoclonal antibody against kininogen reduces inflammation in the HLA-B27 transgenic rat" pptx
... or a deficiency in high-molecular-mass kininogen. Here we study the effects of monoclonal antibody C11C1, an antibody against high-molecular-mass kininogen that inhibits the binding of high- molecular-mass ... antibody against kinino- gen without inducing side effects or toxicity in either the rat or the mouse model of the disease. Competing interests The author...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Gastrin-releasing peptide, substance P and cytokines in rheumatoid arthritis Paul G Green" pps
... peptide, neuropeptide Y, vasoactive intestinal polypeptide (VIP), BN/GRP and SP were all detectable in synovial fluid, only Commentary Gastrin-releasing peptide, substance P and cytokines in rheumatoid arthritis Paul ... between two neuropeptides, bombesin/gastrin-releasing peptide and substance P, and the proinflammatory cytokine interleukin-6 as well as the e...
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: "Response to commentary by Dixon and Silman on the systematic review and meta-analysis by Bongartz et al" doc
... malignancy and serious infection? Commentary on the meta-analysis by Bongartz et al. Arthritis Res Ther 2006, 8:111. Letter Response to commentary by Dixon and Silman on the systematic review and meta-analysis ... support from and has been a consultant to Amgen, Centocor. References 1. Dixon W, Silman A: Is there an association between anti-TNF...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Inflammation, carotid intima-media thickness and atherosclerosis in rheumatoid arthritis" doc
... Teerlink T, van dorp W, Stehouwer CDA: Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima- media thickness, endothelial function, and ... inflammation. In healthy people, the inflammatory response elicited by vaccination is sufficient to temporarily (and reversibly) impair endothelial function [7]. Reduction of inflammati...
Ngày tải lên: 09/08/2014, 10:22
Báo cáo y học: "Introducing Arthritis Research & Therapy’s 10th anniversary issue, ‘The Scientific Basis of Rheumatology: A Decade of Progress’" pdf
... Gay and colleagues [3] explore the experimental evidence for the Editorial Introducing Arthritis Research & Therapy ’s 10th anniversary issue, ‘The Scientific Basis of Rheumatology: A Decade ... & Therapy’s 10th anniversary. Other articles in this series can be found at: http:/ /arthritis- research. com/sbr The Scientific Basis of Rheumatology:...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: " CD4 count at presentation for HIV care in the United States and Canada: Are those over 50 years more likely to have a delayed presentation" pps
... this article as: Althoff et al.: CD4 count at presentation for HIV care in the United States and Canada: Are those over 50 years more likely to have a delayed presentation? . AIDS Research and Therapy ... p resentation for HIV clinical care Median CD4 count (cells/mm 3 ) at first presentation for HIV clinical care Year &l...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Small ruminant feed systems: perceptions and practices in the transitional zone of Ghan" docx
... also go to the elders and farmers of the study area for their support and co-operation during the study. The help of Mr. Obrien Nyarko and other staff of MOFA, Ejura, during the fieldwork and Mr. ... proposed. The insight gained in this study on farmers’ perceptions and practices relating to small ruminant feeds could guide in the selection and introd...
Ngày tải lên: 10/08/2014, 09:21
Báo cáo y học: "Organic parasite control for poultry and rabbits in British Columbia, Canada" pps
... Access Organic parasite control for poultry and rabbits in British Columbia, Canada Cheryl Lans 1* and Nancy Turner 2 Abstract Plants used for treating endo- and ectoparasites of rabbits and poultry in British ... mortality and induced repellency in adult females of the carmine spider mite (Tetranychus cinnabarinus Boisd.; Acarina: Tetranychidae) and eg...
Ngày tải lên: 10/08/2014, 09:21
Báo cáo y học: " A single site for N-linked glycosylation in the envelope glycoprotein of feline immunodeficiency virus modulates the virus-receptor interaction" ppt
... behaved essentially the same as the pseudotypes bearing the T271I mutant Envs in the entry assay (Fig. 3A and 3B), in the syncytial assay, the Δ2N mutant Envs showed a marked reduction in syncytia ... following in vivo replication of mutant virus [87]. These data suggest that the predicted N- link glycosylation sites at N269 and N342 are critical for maintaini...
Ngày tải lên: 13/08/2014, 05:21
Báo cáo y học: "Adiponectin, retinol-binding protein 4, and leptin in protracted critical illness of pulmonary origin" pps
... 4 Research Adiponectin, retinol-binding protein 4, and leptin in protracted critical illness of pulmonary origin Lies Langouche 1 , Sarah Vander Perre 1 , Jan Frystyk 2 , Allan Flyvbjerg 2 , Troels ... circulating retinol binding protein and protein C inhibitor. J Clin Endocrinol Metab 2007, 92:4306-4312. 21. Bernard AM, Vyskocil AA, Mahieu P, Lauwerys RR: Assessme...
Ngày tải lên: 13/08/2014, 16:21