... signficant increase in urine Cu levels in patients suffering from myocar- dial infarction (MI) (15). Reunanen et al. (1996) found increased levels of serum Cu in patients with CAD (14). In contrast, ... renin activity, blood pressure, coronary artery calcification and prevalent cardiovascular disease (36-41). In conclusion, serum levels of trace elements and...
Ngày tải lên: 25/10/2012, 10:51
... 5787 Amino acids 3–13 and amino acids in and flanking the 23 FxxLF 27 motif modulate the interaction between the N-terminal and ligand-binding domain of the androgen receptor Karine Steketee 1, *, ... AR 3)36 subdomain AR 3)13 in N/C interaction and the role of individual amino acid residues in and flanking the 23 FQNLF 27...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) docx
... prepared using BOBSCRIPT [34]. Ó FEBS 2002 Two 1 : 1 binding modes for distamycin (Eur. J. Biochem. 269) 2875 Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) Koen Uytterhoeven 1 , ... current crystal structures describe the interaction of distamycin in the minor groove of the central CAATTG sequen...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo y học: "Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption" ppt
... collagenases, and Figure 1 Histone deacetylase inhibitors block cartilage glycosaminoglycan and collagen loss induced by IL-1α/OSMHistone deacetylase inhibitors block cartilage glycosaminoglycan and collagen ... gelatin zymography, and collagenase activity assays using both SW1353 chondrosarcoma cells and primary human chondrocytes. The HDAC inhibitors trichostat...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "The 3rd International Meeting on Gene Therapy in Rheumatology and Orthopaedics" pot
... International Meeting on Gene Therapy of Arthritis and Related Disorders (held in Bethesda, MA, USA by the National Institutes of Health in 1998) [1] and the Second International Meeting on Gene ... http://arthritis-research.com/content/7/6/273 Abstract The 3rd International Meeting on Gene Therapy in Rheumatology and Orthopaedics was held in Bost...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "A cell-cycle independent role for p21 in regulating synovial fibroblast migration in rheumatoid arthritis" pps
... cell cycle inhibitor with high homology to p21, also plays a role in regulating cell migration. While our data suggest that FLS lacking p21 have enhanced migratory ability, this recent study reports ... reports that murine embryonic fibroblasts lacking p27 exhibit a dramatic decrease in cell motility, the exact opposite response, in a cell-cycle independent manner. p21 (-/...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rheumatoid arthritis" pot
... therapy in 10 patients with SLE and nine patients with RA. In all patients, BAFF levels increased significantly during B-cell depletion. In contrast, APRIL levels in SLE started out normal and decreased, ... between cytokine levels and B-cell frequencyRelation between cytokine levels and B-cell frequency. (a) Two patients with systemic lupus eryth...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: " High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis" ppsx
... inhibitor Apolipoprotein A α 1 -Antitrypsin PEDF Fibronectin Tetranectin Fibronectin Clustrin H 4 inhibitor α 1 -Antichymotrypsin Pregnancy zone protein Gelsolin α 1 -Acid glycoprotein Fibrinogen S100 Kinninogen ... individuals, including healthy individuals and patients with early and late OA. Our results show clear differences in protein profiles between healthy and diseased SF...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "High frequency of corticosteroid and immunosuppressive therapy in patients with systemic sclerosis despite limited evidence for efficacy" doc
... 1 Use of corticosteroids in systemic sclerosis subtypesUse of corticosteroids in systemic sclerosis subtypes. dcSSc, diffuse cutaneous systemic sclerosis; lcSSc, limited cutaneous systemic sclerosis. ... not for citation purposes) Vol 11 No 2 Research article High frequency of corticosteroid and immunosuppressive therapy in patients with systemi...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: "RANKL increases the level of Mcl-1 in osteoclasts and reduces bisphosphonate-induced osteoclast apoptosis in vitro" pps
... alter the level of Bcl-2 in rabbit osteoclasts but caused a marked increase in the level of Mcl-1, an anti-apop- totic member of the Bcl-2 family that is expressed in cells of the myeloid lineage ... biochemical features of apoptosis and occurred in the absence of changes in the level of Bcl-2 or Bcl-x L . In addition, the loss of Mcl-1...
Ngày tải lên: 09/08/2014, 14:20
Báo cáo y học: "Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids" docx
... (AA). Results 5-LO and 15-LO-1 are present in RA and OA synovium, with 5-LO being mostly expressed in lining and sublining macrophages, neutrophils and mast cells and 15-LO-1 mainly in lining macrophages, ... http:/ /arthritis- research.com/content/11/3/R83 Page 1 of 11 (page number not for citation purposes) Vol 11 No 3 Research article Expression of 5-lipoxygenase a...
Ngày tải lên: 09/08/2014, 14:21
Báo cáo y học: "START lipid/sterol-binding domains are amplified in plants and are predominantly associated with homeodomain transcription factors" potx
... lipid/sterol-binding domains are amplified in plants and are predominantly associated with homeodomain transcription factors<p>A survey of proteins containing lipid/sterol-binding StAR-related ... lipid/sterol-binding domains are amplified in plants and are predominantly associated with homeodomain transcription factors Kathrin Schri...
Ngày tải lên: 09/08/2014, 20:20
Báo cáo y học: " Role of miR-1 and miR-133a in myocardial ischemic postconditioning" pptx
... subsequent myocardial injury, in which apoptosis may play a key role in myocardial IR injury [2]. It is therefore important to find the end ogenous protective mechanism against apop- tosis induced by myocardial ... miR-13 3a, and decrease apoptosis of cardiomyocyte. Myocardial- specific miR-1 and miR-13 3a may play an important role in IPost protection by regulating...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Gastrointestinal complaints in shift-working and day-working nurses in Iran" doc
... A pilot study. Med Pr 2006, 57(1):15-9. doi:10.1186/1740-3391-8-9 Cite this article as: Saberi and Moravveji: Gastrointestinal complaints in shift-working and day-working nurses in Iran. Journal ... Circadian Rhythms 2010, 8:9 http://www.jcircadianrhythms.com/content/8/1/9 Page 4 of 4 SHORT PAPE R Open Access Gastrointestinal complaints in shift-working and day-worki...
Ngày tải lên: 10/08/2014, 09:20
Báo cáo y học: "Association of nail biting and psychiatric disorders in children and their parents in a psychiatrically referred sample of children" ppsx
... purposes) Co-morbidity of psychiatric disorders in children with nail biting and psychiatric characteristic of their parents in a clinical sample Onychophagia or nail biting (NB) is a behavior with a wide ... children and their parents in a psychiatrically referred sample of children Ahmad Ghanizadeh 1,2 Address: 1 Assistant Profes...
Ngày tải lên: 13/08/2014, 18:21