... pilot study of zonisamide augmentation in major depressive patients not responding to a low dose trial with duloxetine: preliminary results on tolerability and clinical effects. Annals of General ... augmentation in major depressive patients not responding to a low dose trial with duloxetine: preliminary results...
Ngày tải lên: 09/08/2014, 01:21
... protection reported in clinical trials are corroborated by changing levels of circulating COMP. Rheumatoid arthritis patients commencing treatment with infliximab (N= 32) or etanercept (N = 17) were monitored ... ame- liorating inflammation [7]. In subsequent trials, the effect of COMP = cartilage oligomeric matrix protein (thrombospondin-5); CRP = C-reactive protein;...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Four-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity" pot
... years. Results Continuation rates of infliximab therapy Of the initial 511 patients enrolled in the study, 507 effectively started infliximab therapy. All patients had long-standing, active, refractory RA, ... primarily maintained to evaluate effectiveness and safety issues [27,28]. Evaluation of the efficacy of long-term therapy shows that, after 4 years of...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Evidence for chronic, peripheral activation of neutrophils in polyarticular juvenile rheumatoid arthritis" pdf
... operative in polyarticular Figure 3 Hierarchical cluster analysis of microarray data in juvenile rheumatoid arthritis (JRA) neutrophilsHierarchical cluster analysis of microarray data in juvenile rheumatoid ... that inhibition of neu- trophil activity may provide a useful means of limiting key aspects of the pathology of polyarticular JRA. Genes down- regulated...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids" docx
... (AA). Results 5-LO and 15-LO-1 are present in RA and OA synovium, with 5-LO being mostly expressed in lining and sublining macrophages, neutrophils and mast cells and 15-LO-1 mainly in lining macrophages, ... http:/ /arthritis- research.com/content/11/3/R83 Page 1 of 11 (page number not for citation purposes) Vol 11 No 3 Research article Expression of 5-lipoxygenase a...
Ngày tải lên: 09/08/2014, 14:21
Báo cáo y học: "Exome sequencing identifies a novel missense variant in RRM2B associated with autosomal recessive progressive external ophthalmoplegia" docx
... missense variant in RRM2B associated with autosomal recessive progressive external ophthalmoplegia Atsushi Takata 1,2,3 , Maiko Kato 4 , Masayuki Nakamura 4 , Takeo Yoshikawa 3 , Shigenobu Kanba 2 , Akira ... Kearns-Sayre syndrome, Pearson syndrome, and Table 1 Summary of the filtering to narrow down the candidates for the causal variant Criteria for the filtering Number...
Ngày tải lên: 09/08/2014, 23:20
Báo cáo y học: "Assessing the effect of HAART on change in quality of life among HIV-infected women." pdf
... important initial information of QOL change for women in the HAART era. In summary, we evaluated the effects of HAART on QOL among women in the WIHS. HAART did not show any long-term effect on QOL changes, ... baseline. Discussion In our study, we attempted to obtain unbiased estimates of HAART effects on QOL in WIHS by minimizing indica- tion bias an...
Ngày tải lên: 10/08/2014, 05:20
Báo cáo y học: "Sub-optimal CD4 reconstitution despite viral suppression in an urban cohort on Antiretroviral Therapy (ART) in sub-Saharan Africa: Frequency and clinical significance" ppt
... citation purposes) AIDS Research and Therapy Open Access Research Sub-optimal CD4 reconstitution despite viral suppression in an urban cohort on Antiretroviral Therapy (ART) in sub-Saharan Africa: ... CD4 cell reconstitution despite sustained viral suppression. We determined the frequency and clinical significance of suboptimal CD4 recon...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "nsomnia in chronic renal patients on dialysis in Saudi Arabia" docx
... these limitations, this study confirms the high prevalence of clinically signifi- cant insomnia in Saudi patients undergoing dialysis. Conclusions/Recommendations Our study clearly demonstrates that ... the ICSD-2 definition for insomnia, which consists of difficulty in falling asleep, waking up too early, frequent awakening with difficulty in falling asleep again and secondary da...
Ngày tải lên: 10/08/2014, 09:20
Báo cáo y học: "Acute myopathy secondary to oral steroid therapy in a 49-year-old man: a case report" docx
... CAS E RE P O R T Open Access Acute myopathy secondary to oral steroid therapy in a 49-year-old man: a case report Muhammad A Khan * , Eric Larson Abstract Introduction: Acute myopathy caused ... by oral corticosteroids is rare. We present a case of myopathy occurring after two doses of methylprednisolone. Typically, acute steroid myopathy occurs with t...
Ngày tải lên: 11/08/2014, 00:22
Báo cáo y học: " Efficacy and safety of once-daily aclidinium in chronic obstructive pulmonary disease" potx
... Efficacy and safety of once-daily aclidinium in chronic obstructive pulmonary disease. Respiratory Research 2011 12:55. Submit your next manuscript to BioMed Central and take full advantage of: ... Lamarca R, Garcia GE, Ferrer P: Safety and pharmacokinetics of single doses of aclidinium bromide, a novel long-acting, inhaled antimuscarinic, in healthy subject...
Ngày tải lên: 12/08/2014, 13:22
Báo cáo y học: "Association of current smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers" pps
... similar airway wall and sputum inflammation as asymptomatic and symptomatic smokers without airway obstruction. Current smoking was associated with airway inflammation in patients with COPD and in ... suggesting that cumulative smoking induces chronic inflammation with subsequent sequelae of airway obstruction. Our results indicate that inflammatory e...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "Pilot study of losartan for pulmonary hypertension in chronic obstructive pulmonary disease" ppt
... consequence of chronic alveolar hypoxia is probably the main contributor to the pathogenesis of pulmonary hypertension in COPD [3,8] although a number of other factors may be involved, including hyperinflation ... findings that angiotensin converting enzyme and angiotensin II are both involved in the pulmonary vascular remodelling associated with hypoxic pulmonary hyperte...
Ngày tải lên: 12/08/2014, 18:22
Báo cáo y học: "SPECT/CT imaging of the lumbar spine in chronic low back pain: a case report" docx
... pool imaging followed by a delayed whole-body scan. SPECT/CT imaging centered over the lumbar spine was subsequently performed on a Symbia T6 (Siemens), a dual-head gamma-camera incor- porating a ... reported that no spinal imaging had been performed in investigation of these complaints. This was confirmed by a review of the patient’s records. Physical Examinatio...
Ngày tải lên: 13/08/2014, 15:21
Báo cáo y học: "Clinical features of invasive bronchial-pulmonary aspergillosis in critically ill patients with chronic obstructive respiratory diseases: a prospective study" doc
... 12 RESEARCH Open Access Clinical features of invasive bronchial-pulmonary aspergillosis in critically ill patients with chronic obstructive respiratory diseases: a prospective study Hangyong He 1† , ... the data in the study, takes responsibility for the integrity of the data and the accuracy of the data analysis, and was responsible for the data verific...
Ngày tải lên: 14/08/2014, 07:21